PMID- 33936939
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240401
IS  - 1016-7315 (Print)
IS  - 2212-5043 (Electronic)
IS  - 1016-7315 (Linking)
VI  - 33
IP  - 1
DP  - 2021
TI  - Effect of Presence of Ramus Intermedius Artery on Location of Culprit Lesions in 
      Acute Left Circumflex Coronary Artery Occlusion.
PG  - 35-40
LID - 10.37616/2212-5043.1238 [doi]
AB  - BACKGROUND AND AIM: Coronary artery anatomy frequently affects location of 
      atherosclerotic plaques and subsequent culprit lesions. We sought to clarify 
      whether presence or absence of Ramus Intermedius coronary artery (RI) would 
      affect location of culprit lesions in acute left circumflex (LCX) coronary artery 
      occlusion. METHODS: The study included 180 patients, 100 with a diagnosis of 
      non-ST elevation myocardial infarction (NSTEMI) and 80 with ST elevation 
      myocardial infarction (STEMI). All culprit lesions were located in the LCX 
      coronary artery. RI group included 45 patients and the No RI group included 135 
      patients. RESULTS: Culprit LCX lesions were similarly located at a comparable 
      distance from LCX ostium in both groups and the presence of RI was not associated 
      with significantly more proximally located culprit LCX lesions (34.7 +/- 15.2 mm 
      compared to 30.8 +/- 17.9 mm respectively, p > 0.05). The frequency distribution of 
      culprit lesions' distance from LCX ostium showed no significant difference 
      between both groups in any of the segments studied (10 mm each). There was no 
      significant difference between both groups regarding markers of myocardial 
      necrosis size as cardiac biomarkers (peak cardiac troponin-T 1077.4 +/- 361.2 pg/dl 
      vs 926 +/- 462.2 pg/dl respectively, p = 0.13), (peak creatine kinase-MB 232.2 +/- 81 
      ng/dl vs 194.7 +/- 99.2 ng/dl respectively, p = 0.07) or left ventricular ejection 
      fraction (EF 46.3 +/- 6.3% vs 48.3 +/- 8.3% respectively, p = 0.76). CONCLUSION: 
      Presence of RI coronary artery, as an additional flow divider, may not be 
      associated with more proximal culprit lesions, compared to its absence, in cases 
      of acute LCX coronary artery occlusion. Possible underlying pathophysiologic 
      mechanisms remain to be clarified.
CI  - (c) 2021 Saudi Heart Association.
FAU - El Zayat, Ahmed
AU  - El Zayat A
AD  - Cardiology Department, Faculty of Medicine, Zagazig University, Egypt.
FAU - Eldeeb, Mohey
AU  - Eldeeb M
AD  - Cardiology Department, Faculty of Medicine, Zagazig University, Egypt.
FAU - Gad, Marwa
AU  - Gad M
AD  - Cardiology Department, Faculty of Medicine, Zagazig University, Egypt.
FAU - Ibrahim, Ismail M
AU  - Ibrahim IM
AD  - Cardiology Department, Faculty of Medicine, Zagazig University, Egypt.
LA  - eng
PT  - Journal Article
DEP - 20210419
PL  - Saudi Arabia
TA  - J Saudi Heart Assoc
JT  - Journal of the Saudi Heart Association
JID - 9887261
PMC - PMC8084308
OTO - NOTNLM
OT  - Culprit lesion
OT  - Left circumflex coronary artery
OT  - NSTEMI
OT  - Ramus intermedius artery
OT  - STEMI
COIS- Conflicts of interest None to declare.
EDAT- 2021/05/04 06:00
MHDA- 2021/05/04 06:01
PMCR- 2021/04/19
CRDT- 2021/05/03 06:19
PHST- 2020/10/10 00:00 [received]
PHST- 2021/01/18 00:00 [revised]
PHST- 2021/01/27 00:00 [accepted]
PHST- 2021/05/03 06:19 [entrez]
PHST- 2021/05/04 06:00 [pubmed]
PHST- 2021/05/04 06:01 [medline]
PHST- 2021/04/19 00:00 [pmc-release]
AID - sha-33-01-035 [pii]
AID - 10.37616/2212-5043.1238 [doi]
PST - epublish
SO  - J Saudi Heart Assoc. 2021 Apr 19;33(1):35-40. doi: 10.37616/2212-5043.1238. 
      eCollection 2021.