PMID- 33942447
OWN - NLM
STAT- MEDLINE
DCOM- 20210924
LR  - 20220531
IS  - 1365-2516 (Electronic)
IS  - 1351-8216 (Print)
IS  - 1351-8216 (Linking)
VI  - 27
IP  - 4
DP  - 2021 Jul
TI  - The SLIM study-Shared medical appointments to change lifestyles of overweight 
      people with haemophilia: A randomized multiple baseline (n-of-1) design.
PG  - 606-617
LID - 10.1111/hae.14306 [doi]
AB  - INTRODUCTION: People with haemophilia suffer from haemophilic joint disease that 
      may result in physical inactivity and overweight. Shared medical appointments 
      (SMAs) might help limit the consequences of haemophilic arthropathy. SMAs are 
      group meetings supervised by one or more healthcare professionals that can be 
      utilized to improve lifestyle. AIM: To evaluate the feasibility and efficacy of 
      SMAs in people with haemophilia to improve physical activity and eating habits. 
      METHODS: A multiple baseline single-case design was used. Overweight people with 
      haemophilia were eligible to participate. Seven weekly SMAs were conducted using 
      multiple behavioural change techniques to improve physical activity and eating 
      habits. Feasibility of SMAs was evaluated using (a) dropout rate, (b) occurrence 
      of adverse events (AEs), (c) adherence rate and (d) patient satisfaction. During 
      13 weeks, physical activity was measured daily and eating habits were measured 
      three times per week. The efficacy of SMAs was determined using randomization 
      tests and visual data inspection. RESULTS: Out of the six men participating in 
      the study, one participant dropped out. No study-related AEs occurred. The 
      adherence rate of SMAs was 80%, and participants reported to be 'very satisfied' 
      with the SMAs. Randomization tests and visual analyses demonstrated (statistical) 
      improvements in physical activity (p = .03). No effect was found in self-reported 
      eating habits (p = .55). CONCLUSION: Shared medical appointments are feasible in 
      people with haemophilia and appear to improve physical activity. The effect on 
      improving eating habits could not be established. Scientific replication of our 
      approach is warranted to confirm or refute the merit of SMAs in people with 
      haemophilia.
CI  - (c) 2021 The Authors. Haemophilia published by John Wiley & Sons Ltd.
FAU - Hendriks, Marcel A L
AU  - Hendriks MAL
AUID- ORCID: 0000-0001-5853-1160
AD  - Department of Health Innovations and Technology, Research Group Empowering 
      Healthy Behaviour, Fontys University of Applied Sciences, Eindhoven, the 
      Netherlands.
AD  - Radboud Institute for Health Sciences, IQ Healthcare, Radboud university medical 
      center, Nijmegen, the Netherlands.
FAU - van Wanroij, Johanna W M
AU  - van Wanroij JWM
AD  - Department of Haematology, Radboud university medical center, Nijmegen, the 
      Netherlands.
FAU - Laros-van Gorkom, Britta A P
AU  - Laros-van Gorkom BAP
AD  - Department of Haematology, Radboud university medical center, Nijmegen, the 
      Netherlands.
FAU - Nijhuis-van der Sanden, Maria W G
AU  - Nijhuis-van der Sanden MWG
AD  - Radboud Institute for Health Sciences, IQ Healthcare, Radboud university medical 
      center, Nijmegen, the Netherlands.
FAU - Hoogeboom, Thomas J
AU  - Hoogeboom TJ
AD  - Radboud Institute for Health Sciences, IQ Healthcare, Radboud university medical 
      center, Nijmegen, the Netherlands.
LA  - eng
GR  - Bayer Hemophilia Awards Program Caregiver Award/
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20210504
PL  - England
TA  - Haemophilia
JT  - Haemophilia : the official journal of the World Federation of Hemophilia
JID - 9442916
SB  - IM
MH  - Exercise
MH  - *Hemophilia A/complications/therapy
MH  - Humans
MH  - Life Style
MH  - Male
MH  - Overweight/complications/therapy
MH  - *Shared Medical Appointments
PMC - PMC8360008
OTO - NOTNLM
OT  - Hemophilia
OT  - behaviour therapies
OT  - dietary habits
OT  - group therapy
OT  - physical activity
OT  - self-management
COIS- The authors stated that they had no interest which might be perceived as posing a 
      conflict or bias.
EDAT- 2021/05/05 06:00
MHDA- 2021/09/25 06:00
PMCR- 2021/08/12
CRDT- 2021/05/04 07:16
PHST- 2021/02/22 00:00 [revised]
PHST- 2020/11/17 00:00 [received]
PHST- 2021/03/17 00:00 [accepted]
PHST- 2021/05/05 06:00 [pubmed]
PHST- 2021/09/25 06:00 [medline]
PHST- 2021/05/04 07:16 [entrez]
PHST- 2021/08/12 00:00 [pmc-release]
AID - HAE14306 [pii]
AID - 10.1111/hae.14306 [doi]
PST - ppublish
SO  - Haemophilia. 2021 Jul;27(4):606-617. doi: 10.1111/hae.14306. Epub 2021 May 4.