PMID- 33948086
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220422
IS  - 1178-7007 (Print)
IS  - 1178-7007 (Electronic)
IS  - 1178-7007 (Linking)
VI  - 14
DP  - 2021
TI  - Association of Glycated Albumin/Glycosylated Hemoglobin Ratio with Blood Glucose 
      Fluctuation and Long-Term Blood Glucose Control in Patients with Type 2 Diabetes 
      Mellitus.
PG  - 1809-1815
LID - 10.2147/DMSO.S297730 [doi]
AB  - OBJECTIVE: This study aimed to investigate the association of the glycated 
      albumin (GA)/glycosylated hemoglobin (HbA1c) ratio with the mean amplitude of 
      glycemic excursion (MAGE) in type 2 diabetes mellitus (T2DM). METHODS: A total of 
      102 patients with T2DM who were first treated in Jinjiang Hospital of Fujian 
      Province were enrolled in this study. The patients' general clinical data, 
      including HbA1c, GA, fasting blood glucose, and fasting and peak C-peptide values 
      upon diagnosis and after one year of follow-up, were collected, and their MAGE 
      was calculated. RESULTS: With the increase of the GA/HbA1c ratio at baseline, the 
      patients' fasting and peak C-peptide values decreased gradually from baseline to 
      follow-up, while their MAGE, HbA1c, and fasting blood glucose increased 
      gradually. A regression analysis demonstrated that the baseline MAGE was 
      independently positively correlated with the GA/HbA1c ratio. A Cox regression 
      analysis demonstrated that a baseline GA/HbA1c ratio of >2.78 was an independent 
      risk factor for poor fasting blood glucose and HbA1c. CONCLUSION: The GA/HbA1c 
      ratio is closely related to the MAGE and islet function in patients with T2DM.
CI  - (c) 2021 Wang et al.
FAU - Wang, Bai-Rong
AU  - Wang BR
AD  - Department of Endocrinology, Medical College of Soochow University, Suzhou 
      215123, Jiangsu, People's Republic of China; PLA Rocket Force Characteristic 
      Medical Center, Beijing, 100088, People's Republic of China.
AD  - Department of Endocrinology, Jinjiang Municipal Hospital, Jinjiang, 362200, 
      People's Republic of China.
FAU - Yao, Jun-Teng
AU  - Yao JT
AD  - Department of Endocrinology, Jinjiang Municipal Hospital, Jinjiang, 362200, 
      People's Republic of China.
FAU - Zheng, Hui
AU  - Zheng H
AD  - Department of Endocrinology, Medical College of Soochow University, Suzhou 
      215123, Jiangsu, People's Republic of China; PLA Rocket Force Characteristic 
      Medical Center, Beijing, 100088, People's Republic of China.
FAU - Li, Quan-Min
AU  - Li QM
AD  - Department of Endocrinology, Medical College of Soochow University, Suzhou 
      215123, Jiangsu, People's Republic of China; PLA Rocket Force Characteristic 
      Medical Center, Beijing, 100088, People's Republic of China.
LA  - eng
PT  - Journal Article
DEP - 20210427
PL  - New Zealand
TA  - Diabetes Metab Syndr Obes
JT  - Diabetes, metabolic syndrome and obesity : targets and therapy
JID - 101515585
PMC - PMC8088300
OTO - NOTNLM
OT  - blood glucose control
OT  - blood glucose fluctuation
OT  - glycated albumin
OT  - glycosylated hemoglobin
OT  - type 2 diabetes mellitus
COIS- The authors declare that they have no competing interests.
EDAT- 2021/05/06 06:00
MHDA- 2021/05/06 06:01
PMCR- 2021/04/27
CRDT- 2021/05/05 06:23
PHST- 2020/12/16 00:00 [received]
PHST- 2021/03/04 00:00 [accepted]
PHST- 2021/05/05 06:23 [entrez]
PHST- 2021/05/06 06:00 [pubmed]
PHST- 2021/05/06 06:01 [medline]
PHST- 2021/04/27 00:00 [pmc-release]
AID - 297730 [pii]
AID - 10.2147/DMSO.S297730 [doi]
PST - epublish
SO  - Diabetes Metab Syndr Obes. 2021 Apr 27;14:1809-1815. doi: 10.2147/DMSO.S297730. 
      eCollection 2021.