PMID- 33949211
OWN - NLM
STAT- MEDLINE
DCOM- 20211101
LR  - 20230705
IS  - 1940-1574 (Electronic)
IS  - 0003-3197 (Linking)
VI  - 72
IP  - 10
DP  - 2021 Nov
TI  - The Atherogenic Index of Plasma: A Powerful and Reliable Predictor for Coronary 
      Artery Disease in Patients With Type 2 Diabetes.
PG  - 934-941
LID - 10.1177/00033197211012129 [doi]
AB  - We evaluated the predictive power of the atherogenic index of plasma (AIP) for 
      coronary artery disease (CAD) in patients with type 2 diabetes mellitus (T2DM). A 
      total of 3278 patients who underwent coronary angiography were consecutively 
      enrolled, including 2052 patients with CAD and 1226 patients with T2DM but 
      without CAD. Patients in the CAD group had higher levels of triglyceride (TG), 
      total cholesterol, low-density lipoprotein cholesterol, AIP and a lower level of 
      high-density lipoprotein cholesterol (HDL-C). In correlation analyses, AIP 
      correlated positively with body mass index, log (homeostasis model assessment of 
      insulin resistance), TG, remnant lipoprotein cholesterol, non-HDL-C, but 
      negatively with age and HDL-C. Multivariate logistic regression analyses 
      demonstrated that AIP was an independent risk factor for CAD in diabetic patients 
      and was validated by multiple models. Furthermore, the ORs for CAD risk were 
      raised with increasing AIP quartiles; ORs of AIP quartiles Q2-Q4 compared with Q1 
      were 1.56, 1.70, and 2.22, respectively (Ps < .001), which suggested AIP was the 
      lipid parameter that most strongly associated with incident CAD. In conclusion, 
      AIP is a powerful and reliable biomarker for predicting CAD risk beyond 
      individual lipid profiles in patients with T2DM.
FAU - Zhou, Kuo
AU  - Zhou K
AD  - Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University and 
      Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing, People's 
      Republic of China.
FAU - Qin, Zheng
AU  - Qin Z
AUID- ORCID: 0000-0003-3729-3444
AD  - Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University and 
      Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing, People's 
      Republic of China.
FAU - Tian, Jinfan
AU  - Tian J
AD  - Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University and 
      Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing, People's 
      Republic of China.
FAU - Cui, Kongyong
AU  - Cui K
AD  - Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University and 
      Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing, People's 
      Republic of China.
FAU - Yan, Yunfeng
AU  - Yan Y
AD  - Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University and 
      Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing, People's 
      Republic of China.
FAU - Lyu, Shuzheng
AU  - Lyu S
AUID- ORCID: 0000-0002-4243-2341
AD  - Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University and 
      Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing, People's 
      Republic of China.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20210505
PL  - United States
TA  - Angiology
JT  - Angiology
JID - 0203706
RN  - 0 (Cholesterol, HDL)
RN  - 0 (Cholesterol, LDL)
RN  - 0 (Triglycerides)
RN  - 97C5T2UQ7J (Cholesterol)
SB  - IM
CIN - Angiology. 2023 Sep;74(8):801. PMID: 36655348
MH  - Aged
MH  - Beijing/epidemiology
MH  - Cholesterol/*blood
MH  - Cholesterol, HDL/blood
MH  - Cholesterol, LDL/blood
MH  - Coronary Angiography
MH  - Coronary Artery Disease/*blood/diagnostic imaging/epidemiology
MH  - Cross-Sectional Studies
MH  - Diabetes Mellitus, Type 2/*blood/diagnosis/epidemiology
MH  - Dyslipidemias/*blood/complications/diagnosis
MH  - Female
MH  - Humans
MH  - Incidence
MH  - Male
MH  - Middle Aged
MH  - Predictive Value of Tests
MH  - Prognosis
MH  - Risk Assessment
MH  - Risk Factors
MH  - Triglycerides/*blood
OTO - NOTNLM
OT  - atherogenic index of plasma
OT  - coronary artery disease
OT  - dyslipidemia
OT  - type 2 diabetes mellitus
EDAT- 2021/05/06 06:00
MHDA- 2021/11/03 06:00
CRDT- 2021/05/05 08:45
PHST- 2021/05/06 06:00 [pubmed]
PHST- 2021/11/03 06:00 [medline]
PHST- 2021/05/05 08:45 [entrez]
AID - 10.1177/00033197211012129 [doi]
PST - ppublish
SO  - Angiology. 2021 Nov;72(10):934-941. doi: 10.1177/00033197211012129. Epub 2021 May 
      5.