PMID- 33954580 OWN - NLM STAT- MEDLINE DCOM- 20220224 LR - 20220224 IS - 1528-8951 (Electronic) IS - 0148-0731 (Linking) VI - 143 IP - 10 DP - 2021 Oct 1 TI - Biomechanical Analysis of Head Subjected to Blast Waves and the Role of Combat Protective Headgear Under Blast Loading: A Review. LID - 100801 [pii] LID - 10.1115/1.4051047 [doi] AB - Blast-induced traumatic brain injury (bTBI) is a rising health concern of soldiers deployed in modern-day military conflicts. For bTBI, blast wave loading is a cause, and damage incurred to brain tissue is the effect. There are several proposed mechanisms for the bTBI, such as direct cranial entry, skull flexure, thoracic compression, blast-induced acceleration, and cavitation that are not mutually exclusive. So the cause-effect relationship is not straightforward. The efficiency of protective headgears against blast waves is relatively unknown as compared with other threats. Proper knowledge about standard problem space, underlying mechanisms, blast reconstruction techniques, and biomechanical models are essential for protective headgear design and evaluation. Various researchers from cross disciplines analyze bTBI from different perspectives. From the biomedical perspective, the physiological response, neuropathology, injury scales, and even the molecular level and cellular level changes incurred during injury are essential. From a combat protective gear designer perspective, the spatial and temporal variation of mechanical correlates of brain injury such as surface overpressure, acceleration, tissue-level stresses, and strains are essential. This paper outlines the key inferences from bTBI studies that are essential in the protective headgear design context. CI - Copyright (c) 2021 by ASME. FAU - Sundar, Shyam AU - Sundar S AD - Department of Civil Engineering, Indian Institute of Technology Madras, Chennai 600036, India. FAU - Ponnalagu, Alagappan AU - Ponnalagu A AD - Department of Civil Engineering, Indian Institute of Technology Madras, Chennai 600036, India. LA - eng PT - Journal Article PL - United States TA - J Biomech Eng JT - Journal of biomechanical engineering JID - 7909584 SB - IM MH - *Head Protective Devices OTO - NOTNLM OT - bTBI OT - blast injury biomechanics OT - blast mitigation OT - blast waves OT - combat helmet OT - protective headgear OT - shock tube EDAT- 2021/05/07 06:00 MHDA- 2022/02/25 06:00 CRDT- 2021/05/06 07:12 PHST- 2020/08/31 00:00 [received] PHST- 2021/05/07 06:00 [pubmed] PHST- 2022/02/25 06:00 [medline] PHST- 2021/05/06 07:12 [entrez] AID - 1108858 [pii] AID - 10.1115/1.4051047 [doi] PST - ppublish SO - J Biomech Eng. 2021 Oct 1;143(10):100801. doi: 10.1115/1.4051047.