PMID- 33955194
OWN - NLM
STAT- MEDLINE
DCOM- 20211028
LR  - 20211028
IS  - 1932-863X (Electronic)
IS  - 1932-8621 (Linking)
VI  - 15
IP  - 3
DP  - 2021 Aug
TI  - Comorbid early psychosis and borderline personality disorder: Conceptualizing 
      clinical overlap, etiology, and treatment.
PG  - 208-222
LID - 10.1002/pmh.1509 [doi]
AB  - Despite substantial efforts aimed at the detection and intervention for early 
      symptoms of mental illness, there is relatively limited research on the clinical 
      overlap between borderline personality disorder (BPD) and early psychosis, for 
      example, clinical high risk (CHR) for psychosis, in young people. We present a 
      narrative review of the clinical overlap between BPD and psychosis spectrum 
      symptoms. Both conditions have unstable temporal course, and both are marked by 
      functional impairment, increased suicide risk, and higher rates of psychiatric 
      inpatient services. We then review evidence-based treatments for psychosis and 
      BPD, emphasizing treatments for early presentations of these symptoms and initial 
      research considering treatments for the overlap. Psychotherapies with the 
      strongest empirical support include cognitive behavioral models, with BPD showing 
      limited response to adjunctive pharmacotherapy. We end by discussing specific 
      recommendations for future research, including longitudinal studies to determine 
      the predictors of the course of illness and the development of treatments to 
      target comorbid BPD and CHR symptoms.
CI  - (c) 2021 John Wiley & Sons, Ltd.
FAU - West, Michelle L
AU  - West ML
AD  - CEDAR Clinic and Research Program, Massachusetts Mental Health Center, Boston, 
      Massachusetts, USA.
AD  - Beth Israel Deaconess Medical Center, Department of Psychiatry, Harvard Medical 
      School, Boston, Massachusetts, USA.
AD  - Department of Psychiatry, University of Colorado School of Medicine (CUSOM), 
      Aurora, Colorado, USA.
FAU - Guest, Ryan M
AU  - Guest RM
AD  - Department of Psychology, Emory University, Atlanta, Georgia, USA.
FAU - Carmel, Adam
AU  - Carmel A
AD  - Department of Psychiatry and Behavioral Sciences, University of Washington, 
      Seattle, Washington, USA.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20210505
PL  - England
TA  - Personal Ment Health
JT  - Personality and mental health
JID - 101473502
SB  - IM
MH  - Adolescent
MH  - *Borderline Personality Disorder/complications/epidemiology/therapy
MH  - Humans
MH  - Longitudinal Studies
MH  - Psychotherapy
MH  - *Psychotic Disorders/epidemiology/therapy
MH  - *Suicide
EDAT- 2021/05/07 06:00
MHDA- 2021/10/29 06:00
CRDT- 2021/05/06 07:34
PHST- 2020/04/03 00:00 [received]
PHST- 2021/03/14 00:00 [accepted]
PHST- 2021/05/07 06:00 [pubmed]
PHST- 2021/10/29 06:00 [medline]
PHST- 2021/05/06 07:34 [entrez]
AID - 10.1002/pmh.1509 [doi]
PST - ppublish
SO  - Personal Ment Health. 2021 Aug;15(3):208-222. doi: 10.1002/pmh.1509. Epub 2021 
      May 5.