PMID- 33956983
OWN - NLM
STAT- MEDLINE
DCOM- 20210625
LR  - 20231213
IS  - 1944-7922 (Electronic)
IS  - 1060-3271 (Linking)
VI  - 104
IP  - 2
DP  - 2021 May 21
TI  - A Simple and Standardized Method for the Determination of Total Solanesol in 
      Potato Leaves and Its Extracts Based on HPLC-MS.
PG  - 479-484
LID - 10.1093/jaoacint/qsaa111 [doi]
AB  - BACKGROUND: Solanesol is an important pharmaceutical intermediate raw material, 
      mainly used to synthesize coenzyme Q10, vitamin K2. It can be found prominent in 
      potato stems and leaves. But now potato stems and leaves are always abandoned or 
      discarded as they are not suitable for use as feed in aquaculture or other 
      purposes. These agricultural waste resources can be reutilized as the 
      corresponding extracts. OBJECTIVE: To develop a simple and standardized method 
      for the detection of total solanesol in potato leaves and its extracts. METHODS: 
      N-hexane was chosen as the extraction solvent for three times in the solanesol 
      extraction from potato leaves. HPLC-MS was used for the detection. RESULTS: The 
      LOQ was 0.3 microg/g and the linear range was from 0.1  to 50 microg/mL. The precision 
      and stability were evaluated by the relative standard deviations (RSDs) of three 
      samples (potato leaves, Extract-1, Extract-2) for interday and intraday. The 
      accuracy of the method was evaluated by the recoveries of three different spiked 
      concentrations of solanesol for three samples, and results showed it ranged from 
      80.7% to 99.0% with RSDs less than 8.7%. CONCLUSIONS: The method we established 
      can provide a simple and standardized way for the extraction and detection of 
      total solanesol. HIGHLIGHTS: The work laid a foundation for the resource 
      reutilization of potato stem and leaf.
CI  - (c) AOAC INTERNATIONAL 2020. All rights reserved. For permissions, please email: 
      journals.permissions@oup.com.
FAU - Lan, Tao
AU  - Lan T
AD  - China National Institute of Standardization, Beijing 100191, PR China.
FAU - Yu, Congcong
AU  - Yu C
AD  - Hebei Guanzhuo Detection Technology Stock CO., Ltd, Shijiazhuang 050000, China.
AD  - Innovation Center of Food Quality and Safety Testing Technology of Hebei 
      Province, Hangzhou, Zhejiang Province 310018, China.
FAU - Li, Ren
AU  - Li R
AD  - China National Institute of Standardization, Beijing 100191, PR China.
FAU - Ma, Zheng
AU  - Ma Z
AD  - Zhejiang Provincial Key Laboratory of Biometrology and Inspection & Quarantine, 
      College of Life Sciences, China Jiliang University, Hangzhou, Zhejiang Province 
      310018, China.
FAU - Xi, Xingjun
AU  - Xi X
AD  - China National Institute of Standardization, Beijing 100191, PR China.
FAU - Chu, Qiao
AU  - Chu Q
AD  - China National Institute of Standardization, Beijing 100191, PR China.
LA  - eng
PT  - Journal Article
PL  - England
TA  - J AOAC Int
JT  - Journal of AOAC International
JID - 9215446
RN  - 0 (Plant Extracts)
RN  - 0 (Terpenes)
RN  - FF31XTR2N4 (solanesol)
SB  - IM
MH  - Chromatography, High Pressure Liquid
MH  - Plant Extracts
MH  - Plant Leaves
MH  - *Solanum tuberosum
MH  - Terpenes
MH  - Nicotiana
EDAT- 2021/05/07 06:00
MHDA- 2021/06/29 06:00
CRDT- 2021/05/06 18:12
PHST- 2020/05/10 00:00 [received]
PHST- 2020/07/13 00:00 [revised]
PHST- 2020/08/04 00:00 [accepted]
PHST- 2021/05/07 06:00 [pubmed]
PHST- 2021/06/29 06:00 [medline]
PHST- 2021/05/06 18:12 [entrez]
AID - 5893477 [pii]
AID - 10.1093/jaoacint/qsaa111 [doi]
PST - ppublish
SO  - J AOAC Int. 2021 May 21;104(2):479-484. doi: 10.1093/jaoacint/qsaa111.