PMID- 33963454
OWN - NLM
STAT- MEDLINE
DCOM- 20211015
LR  - 20211120
IS  - 1352-8661 (Electronic)
IS  - 0968-5243 (Linking)
VI  - 34
IP  - 5
DP  - 2021 Oct
TI  - Comparison of 2D and 3D quiescent-interval slice-selective non-contrast MR 
      angiography in patients with peripheral artery disease.
PG  - 649-658
LID - 10.1007/s10334-021-00927-y [doi]
AB  - OBJECTIVE: To evaluate the potential clinical benefit of the superior spatial 
      resolution of 3D prototype thin-slab stack-of-stars (tsSOS) quiescent-interval 
      slice-selective (QISS) MRA over standard 2D-QISS MRA for the detection peripheral 
      artery disease (PAD), using computed tomography angiography (CTA) as reference. 
      MATERIALS AND METHODS: Twenty-three patients (70 +/- 8 years, 18 men) with PAD who 
      had previously undergone run-off CTA were prospectively enrolled. Patients 
      underwent non-contrast MRA using 2D-QISS and tsSOS-QISS at 1.5 T. Eighteen 
      arterial segments were evaluated for subjective and objective image quality 
      (normalized signal-to-noise, nSNR), vessel sharpness, and area under the curve 
      (AUC) for > 50% stenosis detection. RESULTS: Overall subjective image quality 
      ratings for the entire run-off were not different between tsSOS-QISS and 2D-QISS 
      (3 [3; 4] vs 4 [3; 4], respectively; P = 0.813). Sharpness of primary branch 
      vessels demonstrated improved image quality using tsSOS-QISS compared with 
      2D-QISS (4 [3; 4] vs 3 [2; 3], P = 0.008). Objective image quality measures were 
      not different between 2D-QISS and tsSOS-QISS (nSNR 5.0 +/- 1.9 vs 4.2 +/- 1.8; 
      P = 0.132). AUCs for significant stenosis detection by tsSOS-QISS and 2D-QISS 
      were 0.877 and 0.856, respectively (P = 0.336). DISCUSSION: The prototype 3D 
      tsSOS-QISS technique provides similar accuracy in patients with PAD to a standard 
      commercially available 2D-QISS technique, indicating that the use of relatively 
      thick slices does not limit the diagnostic performance of 2D-QISS. However, 
      subjective image quality for branch vessel depiction is improved using the 3D 
      approach.
CI  - (c) 2021. European Society for Magnetic Resonance in Medicine and Biology (ESMRMB).
FAU - Varga-Szemes, Akos
AU  - Varga-Szemes A
AUID- ORCID: 0000-0002-2781-7462
AD  - Division of Cardiovascular Imaging, Department of Radiology and Radiological 
      Science, Medical University of South Carolina, 25 Courtenay Dr, MSC 226, 
      Charleston, SC, 29425, USA. vargaasz@musc.edu.
FAU - Aouad, Pascale
AU  - Aouad P
AD  - Department of Radiology, Feinberg School of Medicine, Northwestern University, 
      Chicago, IL, USA.
FAU - Schoepf, U Joseph
AU  - Schoepf UJ
AD  - Division of Cardiovascular Imaging, Department of Radiology and Radiological 
      Science, Medical University of South Carolina, 25 Courtenay Dr, MSC 226, 
      Charleston, SC, 29425, USA.
FAU - Emrich, Tilman
AU  - Emrich T
AD  - Division of Cardiovascular Imaging, Department of Radiology and Radiological 
      Science, Medical University of South Carolina, 25 Courtenay Dr, MSC 226, 
      Charleston, SC, 29425, USA.
AD  - Department of Diagnostic and Interventional Radiology, University Medical Center, 
      Mainz, Germany.
AD  - German Center for Cardiovascular Research (DZHK), Partner Site Rhine-Main, Mainz, 
      Germany.
FAU - Yacoub, Basel
AU  - Yacoub B
AD  - Division of Cardiovascular Imaging, Department of Radiology and Radiological 
      Science, Medical University of South Carolina, 25 Courtenay Dr, MSC 226, 
      Charleston, SC, 29425, USA.
FAU - Todoran, Thomas M
AU  - Todoran TM
AD  - Division of Cardiology, Department of Medicine, Medical University of South 
      Carolina, Charleston, SC, USA.
FAU - Koktzoglou, Ioannis
AU  - Koktzoglou I
AD  - Department of Radiology, Northshore University HealthSystem, Evanston, IL, USA.
AD  - University of Chicago Pritzker School of Medicine, Chicago, IL, USA.
FAU - Edelman, Robert R
AU  - Edelman RR
AD  - Department of Radiology, Feinberg School of Medicine, Northwestern University, 
      Chicago, IL, USA.
AD  - Department of Radiology, Northshore University HealthSystem, Evanston, IL, USA.
LA  - eng
GR  - R01 HL130093/HL/NHLBI NIH HHS/United States
GR  - R21 HL126015/HL/NHLBI NIH HHS/United States
PT  - Journal Article
DEP - 20210508
PL  - Germany
TA  - MAGMA
JT  - Magma (New York, N.Y.)
JID - 9310752
RN  - 0 (Contrast Media)
SB  - IM
MH  - Constriction, Pathologic
MH  - Contrast Media
MH  - Humans
MH  - Magnetic Resonance Angiography
MH  - Male
MH  - *Peripheral Arterial Disease/diagnostic imaging
MH  - Reproducibility of Results
OTO - NOTNLM
OT  - Computed tomography angiography
OT  - Magnetic resonance angiography
OT  - Peripheral arterial disease
EDAT- 2021/05/09 06:00
MHDA- 2021/10/16 06:00
CRDT- 2021/05/08 07:06
PHST- 2020/12/18 00:00 [received]
PHST- 2021/04/26 00:00 [accepted]
PHST- 2021/04/23 00:00 [revised]
PHST- 2021/05/09 06:00 [pubmed]
PHST- 2021/10/16 06:00 [medline]
PHST- 2021/05/08 07:06 [entrez]
AID - 10.1007/s10334-021-00927-y [pii]
AID - 10.1007/s10334-021-00927-y [doi]
PST - ppublish
SO  - MAGMA. 2021 Oct;34(5):649-658. doi: 10.1007/s10334-021-00927-y. Epub 2021 May 8.