PMID- 33964390
OWN - NLM
STAT- MEDLINE
DCOM- 20211214
LR  - 20211214
IS  - 1526-3231 (Electronic)
IS  - 0749-8063 (Linking)
VI  - 37
IP  - 12
DP  - 2021 Dec
TI  - Establishing the Minimal Clinically Important Difference and Patient-Acceptable 
      Symptomatic State After Arthroscopic Meniscal Repair and Associated Variables for 
      Achievement.
PG  - 3479-3486
LID - S0749-8063(21)00450-3 [pii]
LID - 10.1016/j.arthro.2021.04.058 [doi]
AB  - PURPOSE: To establish the minimal clinically important difference (MCID) and 
      patient-acceptable symptomatic state (PASS) after arthroscopic meniscal repair 
      and identify the factors associated with achieving these outcomes. METHODS: This 
      is a retrospective study with prospectively collected data. Patient-reported 
      outcome measures (PROMs) were collected from April 2017 to March 2020. All 
      patients who underwent arthroscopic meniscal repair and completed both 
      preoperative and postoperative PROMs were included in the analysis. MCID and PASS 
      were calculated via half the standard deviation of the delta PRO change from 
      baseline (for International Knee Documentation Committee Score [IKDC]) and via 
      anchor-based methodology (Knee Injury and Osteoarthritis Outcome Score [KOOS] 
      subscales). RESULTS: Sixty patients were included in the final analysis. The 
      established MCID threshold values were 10.9 for IKDC, 12.3 for KOOS Symptoms, 
      11.8 for KOOS Pain, 11.4 for KOOS Activities of Daily Living (ADL), 16.7 for KOOS 
      Sport, and 16.9 for KOOS Quality of Life (QoL). Postoperative scores greater than 
      the following values corresponded to the PASS: 69.0 for IKDC, 75.0 for KOOS 
      Symptoms, 80.6 for KOOS Pain, 92.7 for KOOS ADL, 80.0 for KOOS Sport, and 56.3 
      for KOOS QoL. Higher preoperative PRO scores were associated with lower 
      likelihood of achieving MCID. Concomitant ligament procedures were associated 
      with a higher likelihood of achieving PASS. Tears to both menisci were associated 
      with decreased likelihood of achieving MCID and PASS for IKDC. Horizontal tears 
      were associated with decreased likelihood of achieving PASS for IKDC and KOOS. 
      Complex tears were associated with decreased likelihood of achieving MCID for 
      KOOS. CONCLUSION: Clinically meaningful outcomes such as MCID and PASS were 
      established for meniscal repair surgery using selected PROMs for IKDC and KOOS 
      subscales. Variables more likely to be associated with achieving these outcomes 
      include lower preoperative PRO score and concomitant ligament procedure, whereas 
      higher preoperative PRO score, tearing of both medial and lateral menisci, and 
      horizontal and complex tear classifications were associated with decreased 
      likelihood of achieving these outcomes. LEVEL OF EVIDENCE: IV, retrospective case 
      series.
CI  - Copyright (c) 2021 Arthroscopy Association of North America. Published by Elsevier 
      Inc. All rights reserved.
FAU - Maheshwer, Bhargavi
AU  - Maheshwer B
AD  - University of Cincinnati College of Medicine, Cincinnati, OH, U.S.A.
FAU - Wong, Stephanie E
AU  - Wong SE
AD  - University of California San Francisco Medical Center, San Francisco, CA, U.S.A.
FAU - Polce, Evan M
AU  - Polce EM
AD  - University of Wisconsin College of Medicine, Madison, WI, U.S.A.
FAU - Paul, Katlynn
AU  - Paul K
AD  - Loyola University Chicago, Chicago, IL, U.S.A.
FAU - Forsythe, Brian
AU  - Forsythe B
AD  - Department of Orthopedic Surgery, Rush University Medical Center, Chicago, IL, 
      U.S.A.
FAU - Bush-Joseph, Charles
AU  - Bush-Joseph C
AD  - Department of Orthopedic Surgery, Rush University Medical Center, Chicago, IL, 
      U.S.A.
FAU - Bach, Bernard R
AU  - Bach BR
AD  - Department of Orthopedic Surgery, Rush University Medical Center, Chicago, IL, 
      U.S.A.
FAU - Yanke, Adam B
AU  - Yanke AB
AD  - Department of Orthopedic Surgery, Rush University Medical Center, Chicago, IL, 
      U.S.A.
FAU - Cole, Brian J
AU  - Cole BJ
AD  - Department of Orthopedic Surgery, Rush University Medical Center, Chicago, IL, 
      U.S.A.
FAU - Verma, Nikhil N
AU  - Verma NN
AD  - Department of Orthopedic Surgery, Rush University Medical Center, Chicago, IL, 
      U.S.A.
FAU - Chahla, Jorge
AU  - Chahla J
AD  - Department of Orthopedic Surgery, Rush University Medical Center, Chicago, IL, 
      U.S.A.. Electronic address: jorge.chahla@rushortho.com.
LA  - eng
PT  - Journal Article
DEP - 20210506
PL  - United States
TA  - Arthroscopy
JT  - Arthroscopy : the journal of arthroscopic & related surgery : official 
      publication of the Arthroscopy Association of North America and the International 
      Arthroscopy Association
JID - 8506498
SB  - IM
MH  - Activities of Daily Living
MH  - Humans
MH  - *Minimal Clinically Important Difference
MH  - *Quality of Life
MH  - Retrospective Studies
MH  - Treatment Outcome
EDAT- 2021/05/09 06:00
MHDA- 2021/12/15 06:00
CRDT- 2021/05/08 20:11
PHST- 2020/11/24 00:00 [received]
PHST- 2021/04/16 00:00 [revised]
PHST- 2021/04/24 00:00 [accepted]
PHST- 2021/05/09 06:00 [pubmed]
PHST- 2021/12/15 06:00 [medline]
PHST- 2021/05/08 20:11 [entrez]
AID - S0749-8063(21)00450-3 [pii]
AID - 10.1016/j.arthro.2021.04.058 [doi]
PST - ppublish
SO  - Arthroscopy. 2021 Dec;37(12):3479-3486. doi: 10.1016/j.arthro.2021.04.058. Epub 
      2021 May 6.