PMID- 33967428
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20231111
IS  - 0970-9134 (Print)
IS  - 0973-7723 (Electronic)
IS  - 0970-9134 (Linking)
VI  - 37
IP  - 3
DP  - 2021 May
TI  - LVAD as a bridge to decision complicated with pump thrombosis and infection.
PG  - 341-344
LID - 10.1007/s12055-020-01082-0 [doi]
AB  - Left ventricular assist devices (LVADs) emerged as an effective therapy for the 
      treatment of symptomatic advanced heart failure in spite of maximum tolerated 
      optimal medical treatment. LVADs were initially conceived as a bridge to 
      transplantation, although with the continuing donor shortage, they also serve as 
      a definitive therapy for some patients. Careful evaluation by a multidisciplinary 
      team and proper patient selection are key factors for good outcomes. These 
      patients are very high-risk surgical candidates, and their survival at 1 year 
      after implantation is estimated to be around 81%. We report a unique case of a 
      patient who underwent LVAD implantation as a bridge to candidacy and suffered 
      several complications related to the device. We also present our experience 
      dealing with these complications in a field of limited evidence. This gentleman 
      developed pump thrombosis second- ary to heparin-induced thrombocytopenia, 
      requiring an LVAD exchange during index admission. A year after being discharged 
      from the first episode, he developed mediastinitis, needing removal of the pump, 
      intravenous antibiotics, and veno-arterial extra corporeal membrane oxygenation 
      (VA-ECMO) for hemodynamic support. A new LVAD insertion was required, and the 
      gentleman could be eventually discharged after a prolonged admission.
CI  - (c) Indian Association of Cardiovascular-Thoracic Surgeons 2021.
FAU - Iglesias-Alvarez, Diego
AU  - Iglesias-Alvarez D
AD  - Department of Cardiothoracic Anesthesia, Freeman Hospital Newcastle Upon Tyne NHS 
      Trust, Freeman Rd, High Heaton, Newcastle upon Tyne, NE7 7DN UK. GRID: 
      grid.415050.5. ISNI: 0000 0004 0641 3308
FAU - Pathania, Vikrant
AU  - Pathania V
AD  - Department of Cardiothoracic Anesthesia, Freeman Hospital Newcastle Upon Tyne NHS 
      Trust, Freeman Rd, High Heaton, Newcastle upon Tyne, NE7 7DN UK. GRID: 
      grid.415050.5. ISNI: 0000 0004 0641 3308
LA  - eng
PT  - Case Reports
DEP - 20210109
PL  - India
TA  - Indian J Thorac Cardiovasc Surg
JT  - Indian journal of thoracic and cardiovascular surgery
JID - 8700105
PMC - PMC8079581
OTO - NOTNLM
OT  - ECMO
OT  - LVAD
OT  - Pump infection
OT  - Pump thrombosis
COIS- Conflict of interestThe authors declare that they have no conflicts of interest.
EDAT- 2021/05/11 06:00
MHDA- 2021/05/11 06:01
PMCR- 2022/05/01
CRDT- 2021/05/10 06:17
PHST- 2020/05/18 00:00 [received]
PHST- 2020/10/16 00:00 [revised]
PHST- 2020/10/21 00:00 [accepted]
PHST- 2021/05/10 06:17 [entrez]
PHST- 2021/05/11 06:00 [pubmed]
PHST- 2021/05/11 06:01 [medline]
PHST- 2022/05/01 00:00 [pmc-release]
AID - 1082 [pii]
AID - 10.1007/s12055-020-01082-0 [doi]
PST - ppublish
SO  - Indian J Thorac Cardiovasc Surg. 2021 May;37(3):341-344. doi: 
      10.1007/s12055-020-01082-0. Epub 2021 Jan 9.