PMID- 33968213
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240401
IS  - 1793-9453 (Electronic)
IS  - 1793-8759 (Print)
IS  - 1793-9453 (Linking)
VI  - 13
IP  - 2
DP  - 2021 Jun
TI  - Conception of Saviour Siblings: Ethical Perceptions of Selected Stakeholders in 
      Malaysia.
PG  - 167-178
LID - 10.1007/s41649-021-00166-2 [doi]
AB  - The conception of saviour siblings using preimplantation genetic diagnosis 
      coupled with human leukocyte antigen (HLA) typing or HLA typing alone is 
      controversial and receives a wide divergence of legal responses among countries 
      around the world. The resulting child conceived through this procedure is dubbed 
      a 'saviour sibling' as the child can potentially act as a compatible donor for an 
      elder ailing sibling who needs a haematopoietic stem cell transplantation. At 
      present, the acceptability of this procedure in Malaysia is ambiguous as there is 
      no specific statute governing assisted reproductive technology, and the guideline 
      issued by the Malaysian Medical Council does not expressly address this issue. 
      The ethical arguments relating to the conception of saviour siblings in the 
      current literature are mainly thought to reflect a liberal viewpoint which is 
      predominantly Western in nature. This paper seeks to explore the perception of 
      selected key stakeholders on the acceptability of and ethical concerns related to 
      this procedure in the Malaysian context. The findings indicate that stakeholders 
      generally support the conception of saviour siblings and some of their concerns 
      echo the Western viewpoint. Interestingly, many were highly anxious about its 
      economic implication, which is rarely discussed in the current literature on 
      saviour siblings.
CI  - (c) National University of Singapore and Springer Nature Singapore Pte Ltd. 2021.
FAU - Kuek, Chee Ying
AU  - Kuek CY
AUID- ORCID: 0000-0001-5545-2846
AD  - Faculty of Law, Multimedia University, Melaka, Malaysia. GRID: grid.411865.f. 
      ISNI: 0000 0000 8610 6308
FAU - Gurmukh Singh, Sharon Kaur A/P
AU  - Gurmukh Singh SKA
AD  - Faculty of Law, University of Malaya, Kuala Lumpur, Malaysia. GRID: 
      grid.10347.31. ISNI: 0000 0001 2308 5949
FAU - Tay, Pek San
AU  - Tay PS
AD  - Advocate & Solicitor, High Court of Malaya, Selangor, Malaysia.
LA  - eng
PT  - Journal Article
DEP - 20210317
PL  - England
TA  - Asian Bioeth Rev
JT  - Asian bioethics review
JID - 101608807
PMC - PMC8079567
OTO - NOTNLM
OT  - Assisted Reproduction
OT  - Ethical perceptions
OT  - HLA typing
OT  - Haematopoietic stem cell transplantation
OT  - Malaysia
OT  - Preimplantation genetic diagnosis
OT  - Saviour sibling
COIS- Competing InterestsThe authors declare that they have no competing interests.
EDAT- 2021/05/11 06:00
MHDA- 2021/05/11 06:01
PMCR- 2022/06/01
CRDT- 2021/05/10 06:22
PHST- 2020/12/21 00:00 [received]
PHST- 2021/01/26 00:00 [revised]
PHST- 2021/01/27 00:00 [accepted]
PHST- 2021/05/10 06:22 [entrez]
PHST- 2021/05/11 06:00 [pubmed]
PHST- 2021/05/11 06:01 [medline]
PHST- 2022/06/01 00:00 [pmc-release]
AID - 166 [pii]
AID - 10.1007/s41649-021-00166-2 [doi]
PST - epublish
SO  - Asian Bioeth Rev. 2021 Mar 17;13(2):167-178. doi: 10.1007/s41649-021-00166-2. 
      eCollection 2021 Jun.