PMID- 33970476
OWN - NLM
STAT- MEDLINE
DCOM- 20210917
LR  - 20220531
IS  - 1090-3941 (Print)
IS  - 1090-3941 (Linking)
VI  - 38
DP  - 2021 May 20
TI  - Blood Flow Quantification in Peripheral Arterial Disease: Emerging Diagnostic 
      Techniques in Vascular Surgery.
PG  - 294-304
LID - 10.52198/21.STI.38.CV1410 [doi]
AB  - The assessment of local blood flow patterns in patients with peripheral arterial 
      disease is clinically relevant, since these patterns are related to 
      atherosclerotic disease progression and loss of patency in stents placed in 
      peripheral arteries, through mechanisms such as recirculating flow and low wall 
      shear stress (WSS). However, imaging of vascular flow in these patients is 
      technically challenging due to the often complex flow patterns that occur near 
      atherosclerotic lesions. While several flow quantification techniques have been 
      developed that could improve the outcomes of vascular interventions, accurate 2D 
      or 3D blood flow quantification is not yet used in clinical practice. This 
      article provides an overview of several important topics that concern the 
      quantification of blood flow in patients with peripheral arterial disease. The 
      hemodynamic mechanisms involved in the development of atherosclerosis and the 
      current clinical practice in the diagnosis of this disease are discussed, showing 
      the unmet need for improved and validated flow quantification techniques in daily 
      clinical practice. This discussion is followed by a showcase of state-of-the-art 
      blood flow quantification techniques and how these could be used before, during 
      and after treatment of stenotic lesions to improve clinical outcomes. These 
      techniques include novel ultrasound-based methods, Phase-Contrast Magnetic 
      Resonance Imaging (PC-MRI) and Computational Fluid Dynamics (CFD). The last 
      section discusses future perspectives, with advanced (hybrid) imaging techniques 
      and artificial intelligence, including the implementation of these techniques in 
      clinical practice.
FAU - Engelhard, Stefan
AU  - Engelhard S
AD  - Department of Vascular Surgery, Rijnstate, Arnhem, The Netherlands.
AD  - Multi-modality Medical Imaging Group, Technical Medical (TechMed) Centre, 
      University of Twente, Enschede, The Netherlands.
AD  - Physics of Fluids Group, Technical Medical (TechMed) Centre, University of 
      Twente, Enschede, The Netherlands.
FAU - van de Velde, Lennart
AU  - van de Velde L
AD  - Department of Vascular Surgery, Rijnstate, Arnhem, The Netherlands.
AD  - Multi-modality Medical Imaging Group, Technical Medical (TechMed) Centre, 
      University of Twente, Enschede, The Netherlands.
AD  - Physics of Fluids Group, Technical Medical (TechMed) Centre, University of 
      Twente, Enschede, The Netherlands.
FAU - Jebbink, Erik Groot
AU  - Jebbink EG
AD  - Department of Vascular Surgery, Rijnstate, Arnhem, The Netherlands.
AD  - Multi-modality Medical Imaging Group, Technical Medical (TechMed) Centre, 
      University of Twente, Enschede, The Netherlands.
FAU - Jain, Kartik
AU  - Jain K
AD  - Department of Thermal and Fluid Engineering, University of Twente, Enschede, The 
      Netherlands.
FAU - Westenberg, Jos
AU  - Westenberg J
AD  - Department of Radiology, Cardiovascular Imaging Group, Leiden University Medical 
      Center, Leiden, The Netherlands.
FAU - Zeebregts, Clark J
AU  - Zeebregts CJ
AD  - Department of Surgery (Division of Vascular Surgery), University Medical Center 
      Groningen, University of Groningen, Groningen, The Netherlands.
FAU - Versluis, Michel
AU  - Versluis M
AD  - Physics of Fluids Group, Technical Medical (TechMed) Centre, University of 
      Twente, Enschede, The Netherlands.
FAU - Reijnen, Michel M P J
AU  - Reijnen MMPJ
AD  - Department of Vascular Surgery, Rijnstate, Arnhem, The Netherlands.
AD  - Multi-modality Medical Imaging Group, Technical Medical (TechMed) Centre, 
      University of Twente, Enschede, The Netherlands.
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Surg Technol Int
JT  - Surgical technology international
JID - 9604509
SB  - IM
MH  - Artificial Intelligence
MH  - Blood Flow Velocity
MH  - Hemodynamics
MH  - Humans
MH  - Hydrodynamics
MH  - Magnetic Resonance Imaging
MH  - *Peripheral Arterial Disease/diagnostic imaging/surgery
MH  - Stress, Mechanical
EDAT- 2021/05/11 06:00
MHDA- 2021/09/18 06:00
CRDT- 2021/05/10 12:36
PHST- 2021/05/11 06:00 [pubmed]
PHST- 2021/09/18 06:00 [medline]
PHST- 2021/05/10 12:36 [entrez]
AID - sti38/1410 [pii]
AID - 10.52198/21.STI.38.CV1410 [doi]
PST - ppublish
SO  - Surg Technol Int. 2021 May 20;38:294-304. doi: 10.52198/21.STI.38.CV1410.