PMID- 33974220
OWN - NLM
STAT- MEDLINE
DCOM- 20211125
LR  - 20230309
IS  - 1573-2649 (Electronic)
IS  - 0962-9343 (Linking)
VI  - 30
IP  - 9
DP  - 2021 Sep
TI  - Comparison of EQ-5D-3L and metabolic components between patients with 
      hyperhidrosis and the general population: a propensity score matching analysis.
PG  - 2591-2599
LID - 10.1007/s11136-021-02856-8 [doi]
AB  - PURPOSE: It is important to understand the characteristics of patients with 
      hyperhidrosis, which are different from the general population, for treating 
      hyperhidrosis. Sympathetic overactivity, which might play an important role in 
      hyperhidrosis, can contribute to metabolic diseases and the decreased quality of 
      life (QoL). We compared the metabolic components and health-related QoL between 
      patients with hyperhidrosis and the general population. METHODS: We conducted a 
      case-control study and compared the characteristics of the patients 
      (N = 196) with hyperhidrosis and propensity score-matched controls (N = 196) 
      selected from the Korean National Health and Nutrition Examination Survey. 
      Metabolic components and EQ-5D-3L (EQ-5D) index were compared using a two-way 
      mixed analysis of covariance after adjusting for confounders. RESULTS: Patients 
      with hyperhidrosis had significantly higher waist circumference (estimated mean 
      values +/- SD for patients and the control group, 85.5  +/-  10.8 cm vs 81.3  +/-  10.3 
      cm, p < 0.001), blood pressure (SBP, 121.1  +/-  16.9 vs 111.7  +/-  10.3, p < 0.001 
      AND DBP, 77.5  +/-  12.8 vs 73.6  +/-  8.6, p < 0.001, respectively), fasting glucose 
      (97.1  +/-  11.3 vs 91.5  +/-  9.2, p < 0.001), and the number of components of 
      metabolic syndrome (1.4  +/-  1.3 vs 1.0  +/-  1.2, p = 0.002), and significantly 
      lower estimated glomerular filtration rate (144.3  +/-  53.2 vs 158.3  +/-  55.7, 
      p = 0.002) and EQ-5D values (estimated mean values (standard error) for patients 
      and the control group, 0.92 (0.01) vs 0.97 (0.01), p < 0.001) compared to the 
      control group after adjustment. CONCLUSION: The patients with hyperhidrosis had 
      more central obesity and unfavorable metabolic parameters and a lower EQ-5D index 
      compared with the general population, emphasizing clinical importance of 
      hyperhidrosis to be cured in aspect of metabolic components as well as patients' 
      QOL.
CI  - (c) 2021. The Author(s), under exclusive licence to Springer Nature Switzerland AG.
FAU - Lee, Yea-Chan
AU  - Lee YC
AD  - Department of Family Medicine, Yonsei University College of Medicine, 50-1, 
      Yonsei-ro, Seodaemun-gu, Seoul, Korea.
AD  - Department of Family Medicine, Yongin Severance Hospital, Yonsei University 
      College of Medicine, 363, Dongbaekjukjeon-daero, Giheung-gu, Yongin-si, 
      Gyoung-gi, Korea.
FAU - You, Young Kyung
AU  - You YK
AD  - Department of Family Medicine, Yonsei University College of Medicine, 50-1, 
      Yonsei-ro, Seodaemun-gu, Seoul, Korea.
AD  - Department of Family Medicine, Gangnam Severance Hospital, Yonsei University 
      College of Medicine, 211 Eonju-ro, Gangnam-gu, Seoul, 06273, Republic of Korea.
FAU - Lee, Jun Hyuk
AU  - Lee JH
AD  - Department of Family Medicine, Yongin Severance Hospital, Yonsei University 
      College of Medicine, 363, Dongbaekjukjeon-daero, Giheung-gu, Yongin-si, 
      Gyoung-gi, Korea.
FAU - Moon, Duk Hwan
AU  - Moon DH
AD  - Department of Thoracic and Cardiovascular Surgery, Gangnam Severance Hospital, 
      Yonsei University College of Medicine, 211 Eonju-ro, Gangnam-gu, Seoul, Korea.
FAU - Lee, Sungsoo
AU  - Lee S
AD  - Department of Thoracic and Cardiovascular Surgery, Gangnam Severance Hospital, 
      Yonsei University College of Medicine, 211 Eonju-ro, Gangnam-gu, Seoul, Korea.
FAU - Jeon, Soyoung
AU  - Jeon S
AD  - Biostatistics Collaboration Unit, Department of Research Affairs , Yonsei 
      University College of Medicine, 50-1 Yonsei-ro, Seodaemoon-gu, Seoul, 03722, 
      Republic of Korea.
FAU - Lee, Hye Sun
AU  - Lee HS
AD  - Biostatistics Collaboration Unit, Department of Research Affairs , Yonsei 
      University College of Medicine, 50-1 Yonsei-ro, Seodaemoon-gu, Seoul, 03722, 
      Republic of Korea. hslee1@yuhs.ac.
FAU - Lee, Ji-Won
AU  - Lee JW
AUID- ORCID: 0000-0002-2666-4249
AD  - Department of Family Medicine, Yonsei University College of Medicine, 50-1, 
      Yonsei-ro, Seodaemun-gu, Seoul, Korea. indi5645@yuhs.ac.
AD  - Department of Family Medicine, Gangnam Severance Hospital, Yonsei University 
      College of Medicine, 211 Eonju-ro, Gangnam-gu, Seoul, 06273, Republic of Korea. 
      indi5645@yuhs.ac.
LA  - eng
GR  - 6-2019-0074/Ministry of Trade, Industry and Energy/
PT  - Journal Article
DEP - 20210511
PL  - Netherlands
TA  - Qual Life Res
JT  - Quality of life research : an international journal of quality of life aspects of 
      treatment, care and rehabilitation
JID - 9210257
SB  - IM
MH  - Case-Control Studies
MH  - Humans
MH  - *Hyperhidrosis
MH  - Nutrition Surveys
MH  - Propensity Score
MH  - *Quality of Life/psychology
MH  - Surveys and Questionnaires
OTO - NOTNLM
OT  - Estimated glomerular filtration rate
OT  - Health-related quality of life
OT  - Hyperhidrosis
OT  - Metabolic syndrome
OT  - Sympathetic nervous system
EDAT- 2021/05/12 06:00
MHDA- 2021/11/26 06:00
CRDT- 2021/05/11 12:26
PHST- 2021/04/21 00:00 [accepted]
PHST- 2021/05/12 06:00 [pubmed]
PHST- 2021/11/26 06:00 [medline]
PHST- 2021/05/11 12:26 [entrez]
AID - 10.1007/s11136-021-02856-8 [pii]
AID - 10.1007/s11136-021-02856-8 [doi]
PST - ppublish
SO  - Qual Life Res. 2021 Sep;30(9):2591-2599. doi: 10.1007/s11136-021-02856-8. Epub 
      2021 May 11.