PMID- 33976635
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210514
IS  - 1662-6575 (Print)
IS  - 1662-6575 (Electronic)
IS  - 1662-6575 (Linking)
VI  - 14
IP  - 1
DP  - 2021 Jan-Apr
TI  - Post-Surgery Subcutaneous Seeding of Laryngeal Squamous Cell Carcinoma: A Rare 
      Case.
PG  - 568-572
LID - 10.1159/000510361 [doi]
AB  - Laryngeal squamous cell carcinoma (LSCC) is the most common malignant head and 
      neck cancer, with a 40% recurrence rate in the first 3 years after radical 
      treatment. Recurrence of LSCC mostly comprises lymphogenous metastasis, 
      hematogenic metastasis, and locoregional recurrence, while LSCC seeding is 
      rarest: there are only 4 cases reported in PubMed, and none of them is one of 
      subcutaneous seeding. We report a case with post-surgery subcutaneous seeding of 
      LSCC. The final biopsy demonstrated that the subcutaneous seeding of the LSCC was 
      2 cm away from the primary lesion, with no recurrent foci observed in the larynx 
      and tracheostoma and little relation to the primary lesion. Thus, we drew the 
      conclusion that LSCC surgeries should stick to the principle of the non-tumor 
      technique to prevent subcutaneous seeding.
CI  - Copyright (c) 2021 by S. Karger AG, Basel.
FAU - Jiang, Yongquan
AU  - Jiang Y
AD  - Department of Otolaryngology, Renji Hospital, School of Medicine, Shanghai 
      Jiaotong University, Shanghai, China.
FAU - Cao, Wanxin
AU  - Cao W
AD  - Department of Otolaryngology, Renji Hospital, School of Medicine, Shanghai 
      Jiaotong University, Shanghai, China.
FAU - Luo, Yuanbo
AU  - Luo Y
AD  - School of Medicine, Shanghai Jiaotong University, Shanghai, China.
FAU - Xu, Ji
AU  - Xu J
AD  - Department of Otolaryngology, Renji Hospital, School of Medicine, Shanghai 
      Jiaotong University, Shanghai, China.
FAU - Li, Ying
AU  - Li Y
AD  - Department of Otolaryngology, Renji Hospital, School of Medicine, Shanghai 
      Jiaotong University, Shanghai, China.
FAU - Li, Jiping
AU  - Li J
AD  - Department of Otolaryngology, Renji Hospital, School of Medicine, Shanghai 
      Jiaotong University, Shanghai, China.
LA  - eng
PT  - Case Reports
DEP - 20210322
PL  - Switzerland
TA  - Case Rep Oncol
JT  - Case reports in oncology
JID - 101517601
PMC - PMC8077469
OTO - NOTNLM
OT  - Cancer
OT  - Laryngeal squamous cell carcinoma
OT  - Subcutaneous seeding
COIS- The authors have no conflicting interests to declare.
EDAT- 2021/05/13 06:00
MHDA- 2021/05/13 06:01
PMCR- 2021/03/22
CRDT- 2021/05/12 07:03
PHST- 2020/07/20 00:00 [received]
PHST- 2020/07/21 00:00 [accepted]
PHST- 2021/05/12 07:03 [entrez]
PHST- 2021/05/13 06:00 [pubmed]
PHST- 2021/05/13 06:01 [medline]
PHST- 2021/03/22 00:00 [pmc-release]
AID - cro-0014-0568 [pii]
AID - 10.1159/000510361 [doi]
PST - epublish
SO  - Case Rep Oncol. 2021 Mar 22;14(1):568-572. doi: 10.1159/000510361. eCollection 
      2021 Jan-Apr.