PMID- 33977863
OWN - NLM
STAT- MEDLINE
DCOM- 20211115
LR  - 20211115
IS  - 1745-3682 (Electronic)
IS  - 1745-3674 (Print)
IS  - 1745-3674 (Linking)
VI  - 92
IP  - 5
DP  - 2021 Oct
TI  - Short-term functional outcome after fast-track primary total knee arthroplasty: 
      analysis of 623 patients.
PG  - 602-607
LID - 10.1080/17453674.2021.1925412 [doi]
AB  - Background and purpose - Early functional outcome after total knee arthroplasty 
      (TKA) has been described before, but without focus on the presence of certain 
      functional recovery patterns. We investigated patterns of functional recovery 
      during the first 3 months after TKA and determined characteristics for 
      non-responders in functional outcome.Patients and methods - All primary TKA in a 
      fast-track setting with complete patient-reported outcome measures (PROMs) 
      preoperatively, at 6 weeks, and 3 months postoperatively were included. Included 
      PROMs were Oxford Knee Score (OKS), Knee disability and Osteoarthritis Outcome 
      Score Physical Function Short-Form (KOOS-PS), and EuroQol 5 dimensions (EQ-5D) 
      including the self-rated health Visual Analogue Scale (VAS). Patients with 
      improvement on OKS less than the minimal clinically important difference (MCID) 
      were determined as non-responders at that time point. Characteristics between 
      groups of responders and non-responders in functional recovery were tested for 
      differences: we defined 4 groups a priori, based on the responder status at each 
      time point.Results - 623 patients were included. At 6 weeks OKS, KOOS-PS, and 
      EQ-5D self-rated health VAS were statistically significant improved compared with 
      preoperative scores. The mean improvement was clinically relevant at 6 weeks for 
      KOOS-PS and at 3 months for OKS. Patient characteristics in non-responders were 
      higher BMI and worse scores on EQ-5D items: mobility, self-care, usual 
      activities, and anxiety/depression.Interpretation - Both statistically 
      significant and clinically relevant functional improvement were found in most 
      patients during the first 3 months after primary TKA. Presumed modifiable patient 
      characteristics in non-responders on early functional outcome were BMI and 
      anxiety/depression.
FAU - Van Egmond, Jeroen C
AU  - Van Egmond JC
AD  - Department of Orthopaedics, Reinier Haga Orthopedisch Centrum, Zoetermeer, the 
      Netherlands.
FAU - Hesseling, Brechtje
AU  - Hesseling B
AD  - Department of Orthopaedics, Reinier Haga Orthopedisch Centrum, Zoetermeer, the 
      Netherlands.
FAU - Verburg, Hennie
AU  - Verburg H
AD  - Department of Orthopaedics, Reinier Haga Orthopedisch Centrum, Zoetermeer, the 
      Netherlands.
FAU - Mathijssen, Nina M C
AU  - Mathijssen NMC
AD  - Department of Orthopaedics, Reinier Haga Orthopedisch Centrum, Zoetermeer, the 
      Netherlands.
LA  - eng
PT  - Journal Article
DEP - 20210512
PL  - Sweden
TA  - Acta Orthop
JT  - Acta orthopaedica
JID - 101231512
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Arthroplasty, Replacement, Knee/*rehabilitation
MH  - Disability Evaluation
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Patient Reported Outcome Measures
MH  - Quality of Life
MH  - Recovery of Function/*physiology
PMC - PMC8519557
EDAT- 2021/05/13 06:00
MHDA- 2021/11/16 06:00
PMCR- 2021/05/12
CRDT- 2021/05/12 08:45
PHST- 2021/05/13 06:00 [pubmed]
PHST- 2021/11/16 06:00 [medline]
PHST- 2021/05/12 08:45 [entrez]
PHST- 2021/05/12 00:00 [pmc-release]
AID - 1925412 [pii]
AID - 10.1080/17453674.2021.1925412 [doi]
PST - ppublish
SO  - Acta Orthop. 2021 Oct;92(5):602-607. doi: 10.1080/17453674.2021.1925412. Epub 
      2021 May 12.