PMID- 33984484 OWN - NLM STAT- MEDLINE DCOM- 20220603 LR - 20230703 IS - 1532-9488 (Electronic) IS - 1043-0679 (Print) IS - 1043-0679 (Linking) VI - 34 IP - 2 DP - 2022 Summer TI - Quality of Life Worsens After Surgical Repair of Acute Type A Aortic Dissection. PG - 399-407 LID - S1043-0679(21)00188-X [pii] LID - 10.1053/j.semtcvs.2021.03.040 [doi] AB - This study aimed to determine how acute type A aortic dissection (ATAAD) impacts patients' quality of life. The 36-Item Short Form Survey (SF-36) was used to measure quality of life. The eight SF-36 scales were aggregated into a two-factor summary: physical and mental component summary scales (PCS and MCS). One hundred fourteen patients were included in the ATAAD group and 81 patients in the aortic valve replacement (AVR) group. All patients underwent surgery between June 2007 and December 2018. Surveys were completed after the operation. The mean scaled score of the ATAAD group decreased significantly in all eight domains of the SF-36 survey after aortic dissection repair except mental health. Also, the postsurgery PCS score was significantly lower than the presurgery score (39 vs 49; P < 0.0001). Multivariable regression confirmed the negative impact of ATAAD on postsurgery PCS score and higher presurgery PCS score had a significant positive impact. The postsurgery MCS score did not change significantly (49 vs 50; P = 0.32), but higher preoperative MCS score had a significant positive impact on the postsurgery MCS score. Age, sex, connective tissue disorders, and stroke did not contribute significantly to the postsurgery PCS and MCS scores. The AVR group had significantly increased postsurgery PCS and MCS scores compared to the presurgery scores (47 vs 41; P < 0.0001) and (53 vs 51; P = 0.02) respectively. Patients reported significantly decreased physical health after recovery from acute type A aortic dissection repair. A multidisciplinary approach is needed to improve patients' quality of life. CI - Copyright (c) 2021 Elsevier Inc. All rights reserved. FAU - St Pierre, Emma C AU - St Pierre EC AD - Department of Cardiac Surgery, Michigan Medicine, Ann Arbor, Michigan. FAU - Orelaru, Felix AU - Orelaru F AD - Department of General Surgery, St. Joseph Mercy, Ann Arbor, Michigan. FAU - Naeem, Aroma AU - Naeem A AD - Department of Cardiac Surgery, Michigan Medicine, Ann Arbor, Michigan. FAU - Farhat, Linda AU - Farhat L AD - Department of Cardiac Surgery, Michigan Medicine, Ann Arbor, Michigan. FAU - Wu, Xiaoting AU - Wu X AD - Department of Cardiac Surgery, Michigan Medicine, Ann Arbor, Michigan. FAU - Yang, Bo AU - Yang B AD - Department of Cardiac Surgery, Michigan Medicine, Ann Arbor, Michigan. Electronic address: boya@med.umich.edu. LA - eng GR - K08 HL130614/HL/NHLBI NIH HHS/United States GR - R01 HL141891/HL/NHLBI NIH HHS/United States GR - R01 HL151776/HL/NHLBI NIH HHS/United States PT - Journal Article DEP - 20210511 PL - United States TA - Semin Thorac Cardiovasc Surg JT - Seminars in thoracic and cardiovascular surgery JID - 8917640 SB - IM CIN - Semin Thorac Cardiovasc Surg. 2022 Summer;34(2):408-409. PMID: 34004295 MH - *Aortic Dissection/diagnostic imaging/surgery MH - Aortic Valve/diagnostic imaging/surgery MH - Humans MH - *Quality of Life MH - Surveys and Questionnaires MH - Treatment Outcome PMC - PMC8581075 MID - NIHMS1702563 OTO - NOTNLM OT - Aortic valve replacement OT - Mental health OT - Quality of life OT - SF-36 OT - Type A aortic dissection COIS- Conflict of Interest: None related to this study. EDAT- 2021/05/14 06:00 MHDA- 2022/06/07 06:00 PMCR- 2023/07/01 CRDT- 2021/05/13 20:13 PHST- 2021/02/19 00:00 [received] PHST- 2021/03/04 00:00 [accepted] PHST- 2021/05/14 06:00 [pubmed] PHST- 2022/06/07 06:00 [medline] PHST- 2021/05/13 20:13 [entrez] PHST- 2023/07/01 00:00 [pmc-release] AID - S1043-0679(21)00188-X [pii] AID - 10.1053/j.semtcvs.2021.03.040 [doi] PST - ppublish SO - Semin Thorac Cardiovasc Surg. 2022 Summer;34(2):399-407. doi: 10.1053/j.semtcvs.2021.03.040. Epub 2021 May 11.