PMID- 33992510
OWN - NLM
STAT- MEDLINE
DCOM- 20210628
LR  - 20210628
IS  - 1590-3729 (Electronic)
IS  - 0939-4753 (Linking)
VI  - 31
IP  - 6
DP  - 2021 Jun 7
TI  - Red meat and processed meat consumption and the risk of dyslipidemia in Korean 
      adults: A prospective cohort study based on the Health Examinees (HEXA) study.
PG  - 1714-1727
LID - S0939-4753(21)00057-0 [pii]
LID - 10.1016/j.numecd.2021.02.008 [doi]
AB  - BACKGROUND AND AIMS: There has been conflicting results on the effect of red meat 
      and processed meat intake on the dyslipidemia risk. Moreover, studies in Asian 
      population with lower meat intake than the Western population are lacking. In 
      this study, we aimed to investigate the association between red and processed 
      meat consumption and the dyslipidemia risk by sex among Koreans. METHODS AND 
      RESULTS: A total of 20,407 participants from a prospective cohort were divided 
      into quintiles according to their red meat consumption and tertiles according to 
      their processed meat consumption based on the validated semi-quantitative food 
      frequency questionnaire. The Cox proportional hazards regression analysis was 
      used to estimate the relative risk and 95% confidence interval of dyslipidemia 
      according to red and processed meat consumption. Higher red meat consumption was 
      associated with a 34% and 10% increased risk of hypercholesterolemia in both men 
      and women, and further, a 58% and 17% increased risk of hyper-low-density 
      lipoprotein cholesterolemia and dyslipidemia, in men, compared to the lowest 
      consumption group. Higher processed meat consumption was associated with a 38% 
      and 9% increased risk of hypercholesterolemia, 29% and 18% increased risk of 
      hypertriglyceridemia, and 32% and 10% increased risk of dyslipidemia in both men 
      and women, respectively, compared to the lowest consumption group. CONCLUSION: 
      The results of the present study can provide compelling evidence on Asian 
      population that red and processed meat consumption can lead to a higher risk of 
      dyslipidemia.
CI  - Copyright (c) 2021 The Italian Diabetes Society, the Italian Society for the Study 
      of Atherosclerosis, the Italian Society of Human Nutrition and the Department of 
      Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. 
      All rights reserved.
FAU - Kim, Seong-Ah
AU  - Kim SA
AD  - Department of Urban Society, The Seoul Institute, Seoul, 06756, South Korea. 
      Electronic address: sakim8864@si.re.kr.
FAU - Shin, Sangah
AU  - Shin S
AD  - Department of Food and Nutrition, Chung-Ang University, Gyeonggi-do, 17546, South 
      Korea. Electronic address: ivory8320@cau.ac.kr.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20210213
PL  - Netherlands
TA  - Nutr Metab Cardiovasc Dis
JT  - Nutrition, metabolism, and cardiovascular diseases : NMCD
JID - 9111474
RN  - 0 (Biomarkers)
RN  - 0 (Cholesterol, LDL)
RN  - 0 (Triglycerides)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Biomarkers/blood
MH  - Cholesterol, LDL/*blood
MH  - Diet Surveys
MH  - Dyslipidemias/*blood/diagnosis/epidemiology
MH  - Female
MH  - Food Handling
MH  - Humans
MH  - Male
MH  - *Meat Products/adverse effects
MH  - Middle Aged
MH  - Prospective Studies
MH  - *Red Meat/adverse effects
MH  - Republic of Korea/epidemiology
MH  - Risk Assessment
MH  - Risk Factors
MH  - Sex Factors
MH  - Time Factors
MH  - Triglycerides/*blood
MH  - Up-Regulation
OTO - NOTNLM
OT  - Dyslipidemia
OT  - Hyper-LDL cholesterolemia
OT  - Hypercholesterolemia
OT  - Meat
OT  - Processed meat
OT  - Red meat
COIS- Declaration of competing interest The authors declare no competing interests.
EDAT- 2021/05/17 06:00
MHDA- 2021/06/29 06:00
CRDT- 2021/05/16 20:31
PHST- 2020/09/07 00:00 [received]
PHST- 2020/12/27 00:00 [revised]
PHST- 2021/02/04 00:00 [accepted]
PHST- 2021/05/17 06:00 [pubmed]
PHST- 2021/06/29 06:00 [medline]
PHST- 2021/05/16 20:31 [entrez]
AID - S0939-4753(21)00057-0 [pii]
AID - 10.1016/j.numecd.2021.02.008 [doi]
PST - ppublish
SO  - Nutr Metab Cardiovasc Dis. 2021 Jun 7;31(6):1714-1727. doi: 
      10.1016/j.numecd.2021.02.008. Epub 2021 Feb 13.