PMID- 34004366
OWN - NLM
STAT- MEDLINE
DCOM- 20220201
LR  - 20220201
IS  - 1665-2681 (Print)
IS  - 1665-2681 (Linking)
VI  - 24
DP  - 2021 Sep-Oct
TI  - NAFLD: Challenges and opportunities to address the public health problem in Latin 
      America.
PG  - 100359
LID - S1665-2681(21)00058-2 [pii]
LID - 10.1016/j.aohep.2021.100359 [doi]
AB  - Non-alcoholic fatty liver disease (NAFLD) is reaching epidemic proportions 
      worldwide. Collectively, Latin American countries have some of the highest 
      obesity rates in the world and the fastest-growing prevalence of type 2 diabetes 
      mellitus (T2DM). Since obesity and T2DM are intrinsically linked with NAFLD, 
      epidemiological projections are worrisome. In addition to this adverse 
      epidemiological setting, the region of Latin America faces unique challenges and 
      obstacles to addressing the growing burden of NAFLD. In this article, on the 
      occasion of the International NASH Day on June 10, 2021, we describe the main 
      challenges and opportunities to improve care of people living with NAFLD in Latin 
      America. Among the major challenges to be tackled are: lack of disease awareness, 
      limited educational opportunities for healthcare personnel and general public, 
      health system fragmentation, and lack of effective strategies for the prevention 
      and effective treatment of NAFLD and common comorbidities, namely obesity and 
      T2DM. Wide dissemination of current concepts on NAFLD, and extensive 
      collaboration between scientific societies, governments, non-governmental 
      organizations, pharmaceutical industry, and other stakeholders is urgently needed 
      to advance the NAFLD public health policies agenda that allows us to address this 
      disease with a whole of society approach.
CI  - Copyright (c) 2021. Published by Elsevier Espana, S.L.U.
FAU - Arab, Juan Pablo
AU  - Arab JP
AD  - Departamento de Gastroenterologia, Escuela de Medicina, Facultad de Medicina, 
      Pontificia Universidad Catolica de Chile, Chile.
FAU - Diaz, Luis Antonio
AU  - Diaz LA
AD  - Departamento de Gastroenterologia, Escuela de Medicina, Facultad de Medicina, 
      Pontificia Universidad Catolica de Chile, Chile.
FAU - Dirchwolf, Melisa
AU  - Dirchwolf M
AD  - Unidad de Trasplante Hepatico, Servicio de Hepatologia, Hospital Privado de 
      Rosario, Rosario, Argentina.
FAU - Mark, Henry E
AU  - Mark HE
AD  - EASL International Liver Foundation, Geneva, Switzerland.
FAU - Lazarus, Jeffrey V
AU  - Lazarus JV
AD  - EASL International Liver Foundation, Geneva, Switzerland; Barcelona Institute for 
      Global Health (ISGlobal), Hospital Clinic, University of Barcelona, Spain.
FAU - Vaughan, Elly
AU  - Vaughan E
AD  - Health Policy and Clinical Evidence, The Economist Intelligence Unit, London, 
      United Kingdom.
FAU - Mendez-Sanchez, Nahum
AU  - Mendez-Sanchez N
AD  - Liver Research Unit, Medica Sur Clinic & Foundation, Faculty of Medicine, 
      National Autonomous University of Mexico, Mexico City, 14050, Mexico.
FAU - Oliveira, Claudia P
AU  - Oliveira CP
AD  - Division of Clinical Gastroenterology and Hepatology, Hospital das Clinicas 
      HCFMUSP, Department of Gastroenterology, Faculdade de Medicina, Universidade de 
      Sao Paulo, Sao Paulo, SP, Brazil.
FAU - Gadano, Adrian
AU  - Gadano A
AD  - Liver Unit, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
FAU - Arrese, Marco
AU  - Arrese M
AD  - Departamento de Gastroenterologia, Escuela de Medicina, Facultad de Medicina, 
      Pontificia Universidad Catolica de Chile, Chile. Electronic address: 
      marrese@med.puc.cl.
LA  - eng
PT  - Journal Article
DEP - 20210515
PL  - Mexico
TA  - Ann Hepatol
JT  - Annals of hepatology
JID - 101155885
SB  - IM
MH  - Delivery of Health Care/*organization & administration
MH  - Diabetes Mellitus, Type 2/complications/epidemiology
MH  - *Health Policy
MH  - Humans
MH  - Latin America/epidemiology
MH  - Non-alcoholic Fatty Liver Disease/*epidemiology/*prevention & control
MH  - Obesity/complications/epidemiology
OTO - NOTNLM
OT  - MAFLD
OT  - NAFLD
OT  - NASH
OT  - Non-alcoholic fatty liver disease
OT  - Non-alcoholic steatohepatitis
OT  - Public policies
EDAT- 2021/05/19 06:00
MHDA- 2022/02/02 06:00
CRDT- 2021/05/18 20:28
PHST- 2021/05/06 00:00 [received]
PHST- 2021/05/07 00:00 [accepted]
PHST- 2021/05/19 06:00 [pubmed]
PHST- 2022/02/02 06:00 [medline]
PHST- 2021/05/18 20:28 [entrez]
AID - S1665-2681(21)00058-2 [pii]
AID - 10.1016/j.aohep.2021.100359 [doi]
PST - ppublish
SO  - Ann Hepatol. 2021 Sep-Oct;24:100359. doi: 10.1016/j.aohep.2021.100359. Epub 2021 
      May 15.