PMID- 34007579
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240401
IS  - 2155-0417 (Electronic)
IS  - 2155-0417 (Linking)
VI  - 10
IP  - 4
DP  - 2019
TI  - Anticoagulation with Warfarin: Roles of Adherence, Social Support and Illness 
      Perception.
LID - 10.24926/iip.v10i4.1966 [doi]
AB  - OBJECTIVES: This study was aimed to determine (1) the associations between 
      adherence to warfarin, social support, perception of illness, and demographic 
      factors on the quality of international normalized ratios (INRs); as well as (2) 
      the relationship between the patients' scores in the Malaysian medication 
      adherence scale (MALMAS) and their current INRs. METHOD: This cross-sectional 
      survey was conducted from November 2017 to January 2018 at the warfarin clinic of 
      Jerantut Hospital, Malaysia. RESULTS: Some 58 participants were recruited, of 
      whom 70.7% were diagnosed with atrial fibrillation (AF). Overall, 87.9% of the 
      participants claimed adherence to their warfarin regimens. Patients with 
      good-quality INR therapy were significantly older, had a higher median income and 
      longer appointment durations. In terms of illness perception (IP), participants 
      with good-quality INR therapyhad significantly lower scores in the identity, 
      personal control, and consequence domains. Overall, the total scores for IP were 
      significantly lower in the good-quality INR therapy. Meanwhile, the MALMAS scores 
      were significantly lower in patients with sub-therapeutic current INR. However, 
      there were no associations between warfarin adherence and perceived social 
      support with current TTR. CONCLUSION: Monitoring of demographic factors and IP's 
      domains is vital since they were associated with quality of INR therapy. 
      Meanwhile, the occurrence of sub-therapeutic current INR should raise suspicion 
      of poor adherence in these patients. Overall, IP and MALMAS are useful tools that 
      should be integrated into the patient care protocols.
CI  - (c) Individual authors.
FAU - Mohamed Koya, Saiful Nizam M V
AU  - Mohamed Koya SNMV
AD  - Department of Specialist Pharmacy, Jerantut Hospital, Malaysia.
LA  - eng
PT  - Journal Article
DEP - 20191031
PL  - United States
TA  - Innov Pharm
JT  - Innovations in pharmacy
JID - 101574764
PMC - PMC8051887
OTO - NOTNLM
OT  - Warfarin
OT  - adherence
OT  - illness perception
OT  - social support
OT  - time in therapeutic range
COIS- Conflicts of interest: Author declares no conflicts of interest.
EDAT- 2019/10/31 00:00
MHDA- 2019/10/31 00:01
PMCR- 2019/10/31
CRDT- 2021/05/19 06:50
PHST- 2021/05/19 06:50 [entrez]
PHST- 2019/10/31 00:00 [pubmed]
PHST- 2019/10/31 00:01 [medline]
PHST- 2019/10/31 00:00 [pmc-release]
AID - 10.24926/iip.v10i4.1966 [doi]
PST - epublish
SO  - Innov Pharm. 2019 Oct 31;10(4):10.24926/iip.v10i4.1966. doi: 
      10.24926/iip.v10i4.1966. eCollection 2019.