PMID- 34007712
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210520
IS  - 2155-0417 (Electronic)
IS  - 2155-0417 (Linking)
VI  - 9
IP  - 3
DP  - 2018
TI  - A New Paradigm of Pharmaceutical Drug Delivery Systems (DDS): Challenges for 
      Space, Time, and Shapes.
PG  - 1-13
LID - 10.24926/iip.v9i3.1450 [doi]
AB  - Using 3D food printing with the Internet of Things (IoT) technology, patients can 
      receive diagnoses and prescriptions from their doctors while in the comfort of 
      their homes. The patient-specific prescription has been innovated by converging 
      3D food printing technology with drug delivery systems (DDSs). Quantitative drug 
      dosages can be incorporated into the composition of food and produced in any 
      shape within a short time. Automating food and DDSs makes promising implications 
      for healing patients remotely, as well. Each of these aspects, along with IoT 
      technology, have contributed to increased health care for patients, no matter 
      their location. The quantitative discharge of vitamin C melted in water, 
      mayonnaise, ketchup, and peanut butter has been verified using the Piston Typed 
      Extrusion (PTE) method. Designs with different curves and shapes were repeatedly 
      printed with a head speed of 1.6x10(-2) m/s, and it was confirmed that effective 
      control while printing the shapes was possible. The Hagen-Poiseuille (HP) formula 
      was utilized to simulate the overall printing time. This simulation affirmed that 
      increasing the head speed from 1.6x10(-2) m/s to 4.0x10(-2) m/s had reduced the 
      printing time consistently, but the time was not reduced continuously after 
      4.0x10(-2) m/s, depending on the materials' viscosities and how much curvature 
      exists in the designs. The precision of printing was adjusted within 5% of the 
      theoretical value during printing, and the IoT technology allowed printing of the 
      materials within five minutes, regardless of the patient's location.
CI  - (c) University of Minnesota Libraries Publishing.
FAU - Eo, Jaeseok
AU  - Eo J
AD  - Department of Metallurgical, Materials and Biomedical Engineering, The University 
      of Texas at El Paso, TX, USA.
FAU - Cepeda, Brandon
AU  - Cepeda B
AD  - Department of Metallurgical, Materials and Biomedical Engineering, The University 
      of Texas at El Paso, TX, USA.
FAU - Kim, Jihye
AU  - Kim J
AD  - Center for Printable Materials Certification (CPMC), The University of Texas at 
      El Paso, TX, USA.
FAU - Kim, Namsoo
AU  - Kim N
AD  - Department of Metallurgical, Materials and Biomedical Engineering, The University 
      of Texas at El Paso, TX, USA.
AD  - Center for Printable Materials Certification (CPMC), The University of Texas at 
      El Paso, TX, USA.
LA  - eng
PT  - Journal Article
DEP - 20181026
PL  - United States
TA  - Innov Pharm
JT  - Innovations in pharmacy
JID - 101574764
PMC - PMC6302755
OTO - NOTNLM
OT  - 3D Printing
OT  - Drug Delivery System (DDS)
OT  - Internet of Things (IoT)
OT  - Patient-Customized
OT  - Piston Type Extrusion (PTE)
OT  - Quantitative Control
EDAT- 2018/10/26 00:00
MHDA- 2018/10/26 00:01
PMCR- 2018/10/26
CRDT- 2021/05/19 06:51
PHST- 2021/05/19 06:51 [entrez]
PHST- 2018/10/26 00:00 [pubmed]
PHST- 2018/10/26 00:01 [medline]
PHST- 2018/10/26 00:00 [pmc-release]
AID - 10.24926/iip.v9i3.1450 [doi]
PST - epublish
SO  - Innov Pharm. 2018 Oct 26;9(3):1-13. doi: 10.24926/iip.v9i3.1450. eCollection 
      2018.