PMID- 34016461
OWN - NLM
STAT- MEDLINE
DCOM- 20211020
LR  - 20211020
IS  - 1873-2623 (Electronic)
IS  - 0041-1345 (Linking)
VI  - 53
IP  - 6
DP  - 2021 Jul-Aug
TI  - Expanded Efficacy of Venovenous Extracorporeal Membrane Oxygenation Support for 
      Deceased Donor Liver Transplantation.
PG  - 1813-1816
LID - S0041-1345(21)00213-X [pii]
LID - 10.1016/j.transproceed.2021.02.021 [doi]
AB  - BACKGROUND: Perioperative respiratory failure occurs frequently in liver 
      transplantation (LT) recipients. Venovenous extracorporeal membrane oxygenation 
      (VV-ECMO) has been applied in patients with acute and potentially reversible 
      life-threatening respiratory failure that is unresponsive to conventional 
      therapies. VV-ECMO is used as a bridging device for lung transplantation. 
      However, there are few reports on VV-ECMO as bridging therapy in LT patients with 
      respiratory failure. This study assessed patient outcomes of VV-ECMO after LT and 
      investigated its applicability and safety in LT surgery. METHODS: From January 
      2017 to May 2019, VV-ECMO was applied in 8 deceased donor LT patients at Pusan 
      National University Yangsan Hospital. RESULTS: Patients administered pre- or 
      postoperative VV-ECMO showed a 50% 1-year survival rate and 75% success rate for 
      ECMO weaning. Six patients were administered preoperative VV-ECMO for respiratory 
      failure, of whom 4 patients survived for longer than a year. Two patients who 
      received VV-ECMO for refractory hypoxia during LT died; 1 failed ECMO weaning, 
      and the other was successfully weaned off ECMO but died of other causes. 
      CONCLUSION: VV-ECMO could lower the risk of hypoxemia-related organ failure while 
      awaiting and during LT via better controlled gas exchange without significant 
      acute morbidity. VV-ECMO may expand operability in patients with severe 
      respiratory failure awaiting LT.
CI  - Copyright (c) 2021. Published by Elsevier Inc.
FAU - Park, Soon Ji
AU  - Park SJ
AD  - Department of Anesthesia and Pain Medicine, Pusan National University Yangsan 
      Hospital, 20, Geumo-Ro, Yangsan, Republic of Korea.
FAU - Park, Ju Yeon
AU  - Park JY
AD  - Department of Anesthesiology and Pain Medicine, Daedong Hospital, 187, 
      Chungnyeol-Daero, Dongnae-Gu, Busan, Republic of Korea.
FAU - Ri, Hyun-Su
AU  - Ri HS
AD  - Department of Anesthesia and Pain Medicine, Pusan National University Yangsan 
      Hospital, 20, Geumo-Ro, Yangsan, Republic of Korea.
FAU - Chung, Minwoo
AU  - Chung M
AD  - Department of Anesthesia and Pain Medicine, Pusan National University Yangsan 
      Hospital, 20, Geumo-Ro, Yangsan, Republic of Korea.
FAU - Ryu, Je Ho
AU  - Ryu JH
AD  - Division of Hepato-Biliary-Pancreatic Surgery and Transplantation, Department of 
      Surgery, Pusan National University Yangsan Hospital, 20, Geumo-Ro, Yangsan, 
      Republic of Korea; Department of Anesthesia and Pain Medicine, School of 
      Medicine, Pusan National University, Yangsan, Republic of Korea.
FAU - Lee, Tae Beom
AU  - Lee TB
AD  - Division of Hepato-Biliary-Pancreatic Surgery and Transplantation, Department of 
      Surgery, Pusan National University Yangsan Hospital, 20, Geumo-Ro, Yangsan, 
      Republic of Korea.
FAU - Yoon, Ji-Uk
AU  - Yoon JU
AD  - Department of Anesthesia and Pain Medicine, Pusan National University Yangsan 
      Hospital, 20, Geumo-Ro, Yangsan, Republic of Korea; Department of Anesthesia and 
      Pain Medicine, School of Medicine, Pusan National University, Yangsan, Republic 
      of Korea. Electronic address: nuncoip@hanmail.net.
LA  - eng
PT  - Journal Article
DEP - 20210518
PL  - United States
TA  - Transplant Proc
JT  - Transplantation proceedings
JID - 0243532
SB  - IM
MH  - *Extracorporeal Membrane Oxygenation/adverse effects
MH  - Humans
MH  - *Liver Transplantation/adverse effects
MH  - Living Donors
MH  - Lung Transplantation
MH  - Respiratory Insufficiency/etiology/therapy
MH  - Retrospective Studies
EDAT- 2021/05/22 06:00
MHDA- 2021/10/21 06:00
CRDT- 2021/05/21 05:53
PHST- 2020/09/18 00:00 [received]
PHST- 2020/12/16 00:00 [revised]
PHST- 2021/02/25 00:00 [accepted]
PHST- 2021/05/22 06:00 [pubmed]
PHST- 2021/10/21 06:00 [medline]
PHST- 2021/05/21 05:53 [entrez]
AID - S0041-1345(21)00213-X [pii]
AID - 10.1016/j.transproceed.2021.02.021 [doi]
PST - ppublish
SO  - Transplant Proc. 2021 Jul-Aug;53(6):1813-1816. doi: 
      10.1016/j.transproceed.2021.02.021. Epub 2021 May 18.