PMID- 34016495
OWN - NLM
STAT- MEDLINE
DCOM- 20210917
LR  - 20210917
IS  - 1776-2588 (Electronic)
IS  - 0761-8425 (Linking)
VI  - 38
IP  - 7
DP  - 2021 Sep
TI  - [Treatment of GERD in asthma].
PG  - 733-742
LID - S0761-8425(21)00234-5 [pii]
LID - 10.1016/j.rmr.2021.04.013 [doi]
AB  - Gastro-oesophageal reflux disease (GORD) is one of the most frequent conditions 
      associated with asthma. GORD has an impact on asthma control and quality of life 
      of asthmatic patients. Its treatment relies on lifestyle modifications, 
      anti-acidic treatment with proton pump inhibitors (PPI) and/or surgical 
      management by fundoplication in some situations. The impact of lifestyle 
      modifications has not been analysed on asthma outcomes alone. Several randomised 
      controlled trials assessed the efficacy of PPI on asthma control, peak expiratory 
      flow and/or quality of life. The impact of fundoplication in asthma has mainly 
      been analysed in retrospective or prospective observational studies. This review 
      highlights the limited impact of GORD treatment on asthma control. Current 
      guidelines are to restrict GORD treatment in asthma to asthmatic patients with 
      actual symptomatic GORD. Given the lack of controlled studies, the place of 
      surgical management of GORD in asthma is currently not defined.
CI  - Copyright (c) 2021 SPLF. Published by Elsevier Masson SAS. All rights reserved.
FAU - Launois, C
AU  - Launois C
AD  - Service des maladies respiratoires, CHU de Reims, 45, rue Cognacq-Jay, 51092 
      Reims cedex, France.
FAU - Mulette, P
AU  - Mulette P
AD  - Service des maladies respiratoires, CHU de Reims, 45, rue Cognacq-Jay, 51092 
      Reims cedex, France.
FAU - Ancel, J
AU  - Ancel J
AD  - Service des maladies respiratoires, CHU de Reims, 45, rue Cognacq-Jay, 51092 
      Reims cedex, France.
FAU - Dury, S
AU  - Dury S
AD  - Service des maladies respiratoires, CHU de Reims, 45, rue Cognacq-Jay, 51092 
      Reims cedex, France; EA 4683, universite de Reims Champagne-Ardenne, 51092 Reims, 
      France.
FAU - Hagenburg, J
AU  - Hagenburg J
AD  - Service des maladies respiratoires, CHU de Reims, 45, rue Cognacq-Jay, 51092 
      Reims cedex, France.
FAU - Lebargy, F
AU  - Lebargy F
AD  - Service des maladies respiratoires, CHU de Reims, 45, rue Cognacq-Jay, 51092 
      Reims cedex, France; EA 4683, universite de Reims Champagne-Ardenne, 51092 Reims, 
      France.
FAU - Dormoy, V
AU  - Dormoy V
AD  - Inserm UMR-S 1250, P3Cell, universite de Reims Champagne-Ardenne, 51092 Reims, 
      France.
FAU - Deslee, G
AU  - Deslee G
AD  - Service des maladies respiratoires, CHU de Reims, 45, rue Cognacq-Jay, 51092 
      Reims cedex, France; Inserm UMR-S 1250, P3Cell, universite de Reims 
      Champagne-Ardenne, 51092 Reims, France.
FAU - Perotin, J-M
AU  - Perotin JM
AD  - Service des maladies respiratoires, CHU de Reims, 45, rue Cognacq-Jay, 51092 
      Reims cedex, France; Inserm UMR-S 1250, P3Cell, universite de Reims 
      Champagne-Ardenne, 51092 Reims, France. Electronic address: 
      jmperotin-collard@chu-reims.fr.
LA  - fre
PT  - Journal Article
PT  - Review
TT  - Traitement du reflux gastro-oesophagien dans l'asthme.
DEP - 20210518
PL  - France
TA  - Rev Mal Respir
JT  - Revue des maladies respiratoires
JID - 8408032
RN  - 0 (Proton Pump Inhibitors)
SB  - IM
MH  - *Asthma/complications/epidemiology/therapy
MH  - *Gastroesophageal Reflux/complications/epidemiology/therapy
MH  - Humans
MH  - Observational Studies as Topic
MH  - Proton Pump Inhibitors/therapeutic use
MH  - Quality of Life
MH  - Retrospective Studies
MH  - Treatment Outcome
OTO - NOTNLM
OT  - Asthma
OT  - Asthme
OT  - Fundoplication
OT  - Fundoplicature
OT  - Gastroesophageal reflux disease
OT  - Inhibiteur de la pompe a protons
OT  - Proton pump inhibitor
OT  - Reflux gastro-oesophagien
EDAT- 2021/05/22 06:00
MHDA- 2021/09/18 06:00
CRDT- 2021/05/21 05:54
PHST- 2021/01/18 00:00 [received]
PHST- 2021/03/25 00:00 [accepted]
PHST- 2021/05/22 06:00 [pubmed]
PHST- 2021/09/18 06:00 [medline]
PHST- 2021/05/21 05:54 [entrez]
AID - S0761-8425(21)00234-5 [pii]
AID - 10.1016/j.rmr.2021.04.013 [doi]
PST - ppublish
SO  - Rev Mal Respir. 2021 Sep;38(7):733-742. doi: 10.1016/j.rmr.2021.04.013. Epub 2021 
      May 18.