PMID- 34026947
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220423
IS  - 2352-0477 (Print)
IS  - 2352-0477 (Electronic)
IS  - 2352-0477 (Linking)
VI  - 8
DP  - 2021
TI  - Follow-up aortic dilatation in patients with repaired tetralogy of Fallot using 
      cardiovascular magnetic resonance.
PG  - 100354
LID - 10.1016/j.ejro.2021.100354 [doi]
LID - 100354
AB  - PURPOSE: The study sought to determine the rate of aortic expansion and 
      correlation with somatic growth in patients with repaired tetralogy of Fallot 
      (rTOF), and predictors for determining the annual growth rate of the aorta 
      (Ao-AGR). METHODS: Ninety-four rTOF patients (mean age 14.5 +/- 4.4 years) with two 
      cardiac magnetic resonance tests (CMR) (median duration 52 months, interquartile 
      range, IQR 24-71) were analyzed for aortic diameter (AoD) at the annulus, the 
      sinus of Valsalva (SoV), the sinotubular junction, and the ascending aorta (AAo), 
      and compared with the normal limit AoD (NL-AoD) values. The median age-at-repair 
      was 60 months (IQR 36-84). Ao-AGR and its index (Ao-AGRI) were derived from 
      changes of the AoD and AoD-index, respectively, divided by the duration between 
      the two studies. Three potential predictors (baseline AoD, sex, and 
      age-at-repair) for the progression of Ao-AGR were analyzed. RESULTS: There was a 
      significant larger AoD than NL-AoD (p < 0.001). Slow aortic growth was 
      encountered in 78-85 % of patients. The Ao-AGR was slow, the median AGR ranged 
      from 0.37 mm (IQR 0.13-0.72) at annulus to 0.56 mm (IQR 0.22-0.91) at AAo. There 
      was a regression in Ao-AGRI, ranged from -1.41 mm (IQR -1.94, -0.87) at annulus 
      to -2.36 mm (IQR -3.09, -1.63) at SoV. The three predictors were not correlated 
      with severity of Ao-AGR. CONCLUSION: Most adolescents with rTOF show significant 
      aortic dilatation. There is a slow Ao-AGR with regression of Ao-AGRI, which may 
      suggest that the rate of aortic growth is slower than the somatic growth. There 
      are no significant predictors of the progression of Ao-AGR.
CI  - (c) 2021 The Author(s).
FAU - Siripornpitak, Suvipaporn
AU  - Siripornpitak S
AD  - Department of Diagnostic and Therapeutic Radiology, Faculty of Medicine, 
      Ramathibodi Hospital, Mahidol University, 270 Rama 6 Road, Phayatai, Ratchathewi, 
      Bangkok, 10400, Thailand.
FAU - Sriprachyakul, Apichaya
AU  - Sriprachyakul A
AD  - Department of Diagnostic and Therapeutic Radiology, Faculty of Medicine, 
      Ramathibodi Hospital, Mahidol University, 270 Rama 6 Road, Phayatai, Ratchathewi, 
      Bangkok, 10400, Thailand.
FAU - Wongmetta, Saruntorn
AU  - Wongmetta S
AD  - Department of Diagnostic and Therapeutic Radiology, Faculty of Medicine, 
      Ramathibodi Hospital, Mahidol University, 270 Rama 6 Road, Phayatai, Ratchathewi, 
      Bangkok, 10400, Thailand.
FAU - Samankatiwat, Piya
AU  - Samankatiwat P
AD  - Division of Thoracic Surgery, Department of Surgery, Faculty of Medicine, 
      Ramathibodi Hospital, Mahidol University, 270 Rama 6 Road, Phayatai, Ratchathewi, 
      Bangkok, 10400, Thailand.
FAU - Mokarapong, Pirapat
AU  - Mokarapong P
AD  - Cardiovascular and Thoracic Surgery Unit, Department of Surgery, Institute of 
      Cardiovascular Diseases, Rajavithi Hospital, 2 Phayatai Road, Ratchathewi, 
      Bangkok, 10400, Thailand.
FAU - Wanitkun, Suthep
AU  - Wanitkun S
AD  - Division of Cardiology, Department of Pediatrics, Faculty of Medicine, 
      Ramathibodi Hospital, Mahidol University, 270 Rama 6 Road, Phayatai, Ratchathewi, 
      Bangkok, 10400, Thailand.
LA  - eng
PT  - Journal Article
DEP - 20210512
PL  - England
TA  - Eur J Radiol Open
JT  - European journal of radiology open
JID - 101650225
PMC - PMC8134066
OTO - NOTNLM
OT  - AAo, ascending aorta
OT  - AGR, annual growth rate
OT  - Annual growth rate
OT  - Annual growth rate index
OT  - Ao-AGR, annual growth rate of the aorta
OT  - AoD, aortic diameter
OT  - AoR, aortic root
OT  - Aortic diameter
OT  - Aortic diameter index
OT  - CMR, cardiac magnetic resonance
OT  - Repaired tetralogy of Fallot
OT  - STJ, sinotubular junction
OT  - SoV, sinus of Valsalva
OT  - Somatic growth
OT  - TOF, tetralogy of Fallot
OT  - cine bSSFP, cine balanced steady-state free precession
OT  - rTOF, repaired tetralogy of Fallot
COIS- The authors report no declarations of interest.
EDAT- 2021/05/25 06:00
MHDA- 2021/05/25 06:01
PMCR- 2021/05/12
CRDT- 2021/05/24 08:15
PHST- 2021/03/06 00:00 [received]
PHST- 2021/05/01 00:00 [revised]
PHST- 2021/05/08 00:00 [accepted]
PHST- 2021/05/24 08:15 [entrez]
PHST- 2021/05/25 06:00 [pubmed]
PHST- 2021/05/25 06:01 [medline]
PHST- 2021/05/12 00:00 [pmc-release]
AID - S2352-0477(21)00034-4 [pii]
AID - 100354 [pii]
AID - 10.1016/j.ejro.2021.100354 [doi]
PST - epublish
SO  - Eur J Radiol Open. 2021 May 12;8:100354. doi: 10.1016/j.ejro.2021.100354. 
      eCollection 2021.