PMID- 34031261
OWN - NLM
STAT- MEDLINE
DCOM- 20210831
LR  - 20210831
IS  - 2056-5933 (Electronic)
IS  - 2056-5933 (Linking)
VI  - 7
IP  - 2
DP  - 2021 May
TI  - Cardiovascular risk factors in gout, psoriatic arthritis, rheumatoid arthritis 
      and ankylosing spondylitis: a cross-sectional survey of patients in Western 
      Sweden.
LID - 10.1136/rmdopen-2021-001568 [doi]
LID - e001568
AB  - OBJECTIVES: We aimed to compare traditional (trad) cardiovascular risk factors 
      (CVRFs) among patients with gout, psoriatic arthritis (PsA), rheumatoid arthritis 
      (RA) and ankylosing spondylitis (AS) stratified by sex. METHODS: A survey was 
      sent to patients with gout (n=1589), PsA (n=1200), RA (n=1246) and AS (n=1095). 
      Patients were retrieved from Sahlgrenska University Hospital, the hospitals of 
      Uddevalla and Skovde, and 12 primary care centres in Western Sweden. The 
      prevalence of self-reported trad-CVRFs was compared between diagnoses by age 
      standardisation with the 2018 population of Sweden as the standard population. 
      RESULTS: In total, 2896 (56.5%) of 5130 patients responded. Hypertension was the 
      most frequently found comorbidity, reported by 65% of patients with gout, 41% 
      with PsA, 43% with RA and 29% with AS. After age standardisation, women and men 
      with gout had significantly more obesity (body mass index >/=30 kg/m(2)), 
      hypertension, diabetes, hyperlipidaemia and multiple trad-CVRFs, compared with 
      those with PsA, RA and AS. Obesity was significantly more common in PsA than in 
      RA. In women, obesity, hypertension and multiple trad-CVRFs were more frequently 
      reported in PsA than in RA and AS, whereas similar prevalence of CVRFs and 
      coexistence of multiple trad-CVRFs were found in men with PsA, RA and AS. 
      CONCLUSIONS: Women and men with gout had the highest prevalence of trad-CVRFs. 
      Differences in occurrence of CVRFs by sex were found in patients with PsA, RA and 
      AS. In women, patients with PsA had higher occurrence of trad-CVRFs than those 
      with RA and AS, whereas in men the distribution of CVRFs was similar in PsA, RA 
      and AS.
CI  - (c) Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No 
      commercial re-use. See rights and permissions. Published by BMJ.
FAU - Landgren, Anton Jonatan
AU  - Landgren AJ
AUID- ORCID: 0000-0001-7922-3335
AD  - Department of Rheumatology and Inflammation Research, Institute of Medicine, 
      Sahlgrenska Academy, University of Gothenburg, Sweden 
      anton.landgren@rheuma.gu.se.
AD  - Region Vastra Gotaland, Research and Development Primary Health Care, Gothenburg, 
      Sweden.
FAU - Dehlin, Mats
AU  - Dehlin M
AUID- ORCID: 0000-0001-5165-0968
AD  - Department of Rheumatology and Inflammation Research, Institute of Medicine, 
      Sahlgrenska Academy, University of Gothenburg, Sweden.
FAU - Jacobsson, Lennart
AU  - Jacobsson L
AD  - Department of Rheumatology and Inflammation Research, Institute of Medicine, 
      Sahlgrenska Academy, University of Gothenburg, Sweden.
FAU - Bergsten, Ulrika
AU  - Bergsten U
AUID- ORCID: 0000-0001-5026-7342
AD  - R&D Department at Region Halland, Halmstad, Sweden.
FAU - Klingberg, Eva
AU  - Klingberg E
AUID- ORCID: 0000-0001-6858-6413
AD  - Department of Rheumatology and Inflammation Research, Institute of Medicine, 
      Sahlgrenska Academy, University of Gothenburg, Sweden.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - RMD Open
JT  - RMD open
JID - 101662038
SB  - IM
MH  - *Arthritis, Psoriatic/epidemiology
MH  - *Arthritis, Rheumatoid/epidemiology
MH  - *Cardiovascular Diseases/epidemiology
MH  - Cross-Sectional Studies
MH  - Female
MH  - *Gout/epidemiology
MH  - Heart Disease Risk Factors
MH  - Humans
MH  - Male
MH  - Risk Factors
MH  - *Spondylitis, Ankylosing/complications/epidemiology
MH  - Sweden/epidemiology
PMC - PMC8154995
OTO - NOTNLM
OT  - ankylosing spondylitis
OT  - epidemiology
OT  - gout
OT  - psoriatic arthritis
OT  - rheumatoid arthritis
COIS- Competing interests: None declared.
EDAT- 2021/05/26 06:00
MHDA- 2021/09/01 06:00
PMCR- 2021/05/23
CRDT- 2021/05/25 06:06
PHST- 2021/01/03 00:00 [received]
PHST- 2021/03/26 00:00 [revised]
PHST- 2021/04/22 00:00 [accepted]
PHST- 2021/05/25 06:06 [entrez]
PHST- 2021/05/26 06:00 [pubmed]
PHST- 2021/09/01 06:00 [medline]
PHST- 2021/05/23 00:00 [pmc-release]
AID - rmdopen-2021-001568 [pii]
AID - 10.1136/rmdopen-2021-001568 [doi]
PST - ppublish
SO  - RMD Open. 2021 May;7(2):e001568. doi: 10.1136/rmdopen-2021-001568.