PMID- 34032161 OWN - NLM STAT- MEDLINE DCOM- 20211015 LR - 20211015 IS - 1945-7243 (Electronic) IS - 0046-9580 (Print) IS - 0046-9580 (Linking) VI - 58 DP - 2021 Jan-Dec TI - The Effects of Exercise Interventions on Balance Capacity in Patients with Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis. PG - 469580211018284 LID - 10.1177/00469580211018284 [doi] LID - 00469580211018284 AB - The effect of exercise intervention on balance capacity among type 2 diabetes mellitus (T2DM) patients has not been evaluated. The objective of this systematic review and meta-analysis is to investigate the effect of exercise intervention on balance capacity among T2DM patients compared to the control group (usual care, waitlist, no-treatment, education). We conducted a comprehensive literature search through PubMed, EMBASE, Physiotherapy Evidence Database (PEDro), Cochrane library, Web of Science (WOS) from inception to August 2020. The literature language was limited to English. Randomized controlled trials (RCTs) or quasi-experimental (Q-E) trials that examined the effect of exercise intervention on balance capacity among T2DM patients were included. We used the standard methods of meta-analysis to evaluate the outcomes of exercise intervention for balance capacity of T2DM patients. A total of 14 trials (11 RCTs and 3 Q-E trials) involving 883 participants were eligible. The meta-analysis of some studies demonstrated that exercise intervention could significantly improve Berg Balance Scale (BBS) (MD = 2.56; 95%CI [0.35, 4.77]; P = .02), SLST (Single Leg Stance Test) under the eyes-open (EO) condition (MD = 3.63; 95%CI [1.79, 5.47]; P = .0001) and eyes-close (EC) condition (MD = 0.41; 95%CI [0.10, 0.72]; P = .01) compared to control group. There was no significant difference in Time Up and Go Test (TUGT) (MD = -0.75; 95%CI [-1.69, 0.19]; P = .12) and fall efficacy (SMD = -0.44; 95%CI [-0.86, -0.01]; P = .05). Narrative review of some studies indicated that exercise intervention could improve postural stability measured by Sensory Organization Test (SOT) and Center of Pressure (COP) variables, etc. This systematic review and meta-analysis summarized that exercise intervention could improve balance capacity in T2DM patients. However, further studies with high quality are required to evaluate its effect. FAU - Qin, Jiawei AU - Qin J AUID- ORCID: 0000-0001-6561-7333 AD - College of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, China. AD - Department of Rehabilitation Medicine, Quanzhou First Hospital Affiliated to Fujian Medical University, Quanzhou, China. FAU - Zhao, Kaize AU - Zhao K AD - Fujian Institute of Sports Science, Fuzhou, China. FAU - Chen, Yannan AU - Chen Y AD - College of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, China. FAU - Guo, Shuai AU - Guo S AD - College of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, China. FAU - You, Yue AU - You Y AD - College of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, China. FAU - Xie, Jinjin AU - Xie J AD - College of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, China. FAU - Xu, Ying AU - Xu Y AD - College of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, China. AD - Key Laboratory of Orthopedics & Traumatology of Traditional Chinese Medicne and Rehabilitation (Fujian University of Traditional Chinese Medicine), Ministry of Education, Fuzhou, China. AD - Fujian Key Laboratory of Rehabilitation Technology, Fuzhou, China. FAU - Wu, Jingsong AU - Wu J AD - College of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, China. AD - Key Laboratory of Orthopedics & Traumatology of Traditional Chinese Medicne and Rehabilitation (Fujian University of Traditional Chinese Medicine), Ministry of Education, Fuzhou, China. AD - Fujian Key Laboratory of Rehabilitation Technology, Fuzhou, China. FAU - Liu, Zhizhen AU - Liu Z AUID- ORCID: 0000-0001-9645-9120 AD - College of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, China. AD - Key Laboratory of Orthopedics & Traumatology of Traditional Chinese Medicne and Rehabilitation (Fujian University of Traditional Chinese Medicine), Ministry of Education, Fuzhou, China. AD - Fujian Key Laboratory of Rehabilitation Technology, Fuzhou, China. FAU - Huang, Jia AU - Huang J AD - College of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, China. AD - Key Laboratory of Orthopedics & Traumatology of Traditional Chinese Medicne and Rehabilitation (Fujian University of Traditional Chinese Medicine), Ministry of Education, Fuzhou, China. AD - Fujian Key Laboratory of Rehabilitation Technology, Fuzhou, China. FAU - Chen, Li Dian AU - Chen LD AD - College of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, China. AD - Key Laboratory of Orthopedics & Traumatology of Traditional Chinese Medicne and Rehabilitation (Fujian University of Traditional Chinese Medicine), Ministry of Education, Fuzhou, China. AD - Fujian Key Laboratory of Rehabilitation Technology, Fuzhou, China. FAU - Tao, Jing AU - Tao J AD - College of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, China. AD - Key Laboratory of Orthopedics & Traumatology of Traditional Chinese Medicne and Rehabilitation (Fujian University of Traditional Chinese Medicine), Ministry of Education, Fuzhou, China. AD - Fujian Key Laboratory of Rehabilitation Technology, Fuzhou, China. LA - eng PT - Journal Article PT - Meta-Analysis PT - Research Support, Non-U.S. Gov't PT - Systematic Review PL - United States TA - Inquiry JT - Inquiry : a journal of medical care organization, provision and financing JID - 0171671 SB - IM MH - *Diabetes Mellitus, Type 2/therapy MH - Exercise MH - Exercise Therapy MH - Humans MH - *Postural Balance MH - Randomized Controlled Trials as Topic PMC - PMC8155768 OTO - NOTNLM OT - balance OT - exercise OT - systematic review OT - type 2 diabetes mellitus COIS- Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article. EDAT- 2021/05/26 06:00 MHDA- 2021/10/16 06:00 PMCR- 2021/05/25 CRDT- 2021/05/25 08:39 PHST- 2021/05/25 08:39 [entrez] PHST- 2021/05/26 06:00 [pubmed] PHST- 2021/10/16 06:00 [medline] PHST- 2021/05/25 00:00 [pmc-release] AID - 10.1177_00469580211018284 [pii] AID - 10.1177/00469580211018284 [doi] PST - ppublish SO - Inquiry. 2021 Jan-Dec;58:469580211018284. doi: 10.1177/00469580211018284.