PMID- 34032967
OWN - NLM
STAT- MEDLINE
DCOM- 20210825
LR  - 20210825
IS  - 1613-2246 (Electronic)
IS  - 0021-5155 (Linking)
VI  - 65
IP  - 5
DP  - 2021 Sep
TI  - Peripapillary choroidal thickness assessed by spectral-domain optical coherence 
      tomography in normal Japanese.
PG  - 666-671
LID - 10.1007/s10384-021-00843-7 [doi]
AB  - PURPOSE: To investigate peripapillary choroidal thickness (PPCT) in normal 
      Japanese subjects by using spectral-domain optical coherence tomography (SD-OCT) 
      with enhanced depth imaging (EDI) technique and evaluate its association with 
      ocular and systemic factors. STUDY DESIGN: Cross-sectional study. METHODS: This 
      study included 85 eyes of 85 normal Japanese subjects. Normal subjects were 
      defined as those without retinal and optic nerve disorders of any kind. The PPCT 
      was measured at the location of 3.4 mm diameter peripapillary circle centered on 
      the optic nerve head. It was measured as the distance between the retinal pigment 
      epithelium and scleral-choroidal interface at the following six sectors; 
      temporal, supra-temporal, supra-nasal, nasal, infero-nasal, and infero-temporal. 
      Global PPCT was calculated based on these sectorial data. In addition, 
      association between the PPCT and ocular and systemic factors were evaluated. 
      RESULTS: Among the included subjects, 39 (45.9%) were men and mean age was 
      51.4 +/- 17.6 years. The mean global PPCT was 135.8 +/- 40.6 microm. The infero-nasal and 
      infero-temporal sectors were significantly thinner than other sectors (all, 
      P < 0.05). In multiple regression analysis, thinner global PPCT was significantly 
      associated with older age (P < 0.0001) and female sex (P = 0.0330) after 
      considering effects of other confounders. CONCLUSIONS: This study provided global 
      PPCT and its profile in normal Japanese subjects by using EDI SD-OCT. These 
      results may be used as a reference in the assessment of normal status of the 
      PPCT. The age and sex of the subjects should be considered in interpreting the 
      PPCT data.
CI  - (c) 2021. Japanese Ophthalmological Society.
FAU - Shibata, Hitomi
AU  - Shibata H
AD  - Department of Ophthalmology, Akita University Graduate School of Medicine, 1-1-1 
      Hondo, Akita, Akita, 010-8543, Japan.
FAU - Sawada, Yu
AU  - Sawada Y
AD  - Department of Ophthalmology, Akita University Graduate School of Medicine, 1-1-1 
      Hondo, Akita, Akita, 010-8543, Japan. sawadayu55415@gmail.com.
FAU - Ishikawa, Makoto
AU  - Ishikawa M
AD  - Department of Ophthalmology, Akita University Graduate School of Medicine, 1-1-1 
      Hondo, Akita, Akita, 010-8543, Japan.
FAU - Yoshitomi, Takeshi
AU  - Yoshitomi T
AD  - Department of Fukuoka International, University of Health and Welfare, Fukuoka, 
      Japan.
FAU - Iwase, Takeshi
AU  - Iwase T
AD  - Department of Ophthalmology, Akita University Graduate School of Medicine, 1-1-1 
      Hondo, Akita, Akita, 010-8543, Japan.
LA  - eng
GR  - 17k11417/Japan Society for the Promotion of Science/
PT  - Journal Article
DEP - 20210525
PL  - Japan
TA  - Jpn J Ophthalmol
JT  - Japanese journal of ophthalmology
JID - 0044652
SB  - IM
MH  - Adult
MH  - Aged
MH  - Choroid
MH  - Cross-Sectional Studies
MH  - Female
MH  - Humans
MH  - Japan/epidemiology
MH  - Male
MH  - Middle Aged
MH  - *Optic Disk
MH  - *Tomography, Optical Coherence
OTO - NOTNLM
OT  - Choroidal thickness
OT  - Glaucoma
OT  - Optic nerve head
OT  - Peripapillary choroid
OT  - Spectral-domain optical coherence tomography
EDAT- 2021/05/26 06:00
MHDA- 2021/08/26 06:00
CRDT- 2021/05/25 14:04
PHST- 2020/10/26 00:00 [received]
PHST- 2021/04/22 00:00 [accepted]
PHST- 2021/05/26 06:00 [pubmed]
PHST- 2021/08/26 06:00 [medline]
PHST- 2021/05/25 14:04 [entrez]
AID - 10.1007/s10384-021-00843-7 [pii]
AID - 10.1007/s10384-021-00843-7 [doi]
PST - ppublish
SO  - Jpn J Ophthalmol. 2021 Sep;65(5):666-671. doi: 10.1007/s10384-021-00843-7. Epub 
      2021 May 25.