PMID- 34046894 OWN - NLM STAT- MEDLINE DCOM- 20210819 LR - 20210819 IS - 1097-0096 (Electronic) IS - 0091-2751 (Linking) VI - 49 IP - 7 DP - 2021 Sep TI - Minimally invasive ultrasound-guided vs open release for carpal tunnel syndrome in working population: A randomized controlled trial. PG - 693-703 LID - 10.1002/jcu.23019 [doi] AB - PURPOSE: To compare the clinical effectiveness of minimally invasive ultrasound (US)-guided vs open release for carpal tunnel syndrome. METHODS: In an open randomized controlled trial, 47 employed patients were allocated to US-guided carpal tunnel release (USCTR) and 42 to an open carpal tunnel release (OCTR) procedure. The main outcome was symptom severity measured by the Boston Carpal Tunnel Syndrome Questionnaire (BCTQ-S). Secondary outcomes were hand functionality (BCTQ-F), nerve conduction, two-point discrimination, handgrip and pinch strength, pain (visual analog scale), work leave and complications. For BCTQ-S and BCTQ-F, minimal clinically important differences (MCID) were also considered. Follow-up duration was 12 months. RESULTS: Mixed model analyses detected no significant differences between the two treatment arms in BCTQ-S (P = .098) while BCTQ-F scores were significantly better in the USCTR group (P = .007). This benefit was, however, not supported by the MCID data. Remaining variables were similar in the two groups except pain which was lower in USCTR at 3 months follow-up. All variables but two-point discrimination showed significant improvement after 3 months. CONCLUSIONS: Our findings reveal similar symptom relief benefits following OCTR or USCTR in these patients. The patients in our USCTR group, however, reported better hand functional status and less pain. CI - (c) 2021 Wiley Periodicals LLC. FAU - de la Fuente, Javier AU - de la Fuente J AD - Department of Orthopedic Surgery, Clinica Pakea-Mutualia, San Sebastian, Spain. FAU - Aramendi, Jose F AU - Aramendi JF AUID- ORCID: 0000-0003-3466-6516 AD - Primary Care Department, Clinica Pakea-Mutualia, San Sebastian, Spain. FAU - Ibanez, Jose M AU - Ibanez JM AD - Department of Physical Medicine and Rehabilitation, Clinica Pakea-Mutualia, San Sebastian, Spain. FAU - Blasi, Marc AU - Blasi M AD - Plastic Surgery Department, Hospital Universitari Germans Trias i Pujol, Badalona, Spain. FAU - Vazquez, Alberto AU - Vazquez A AD - Department of Occupational Medicine, Clinica Pakea-Mutualia, San Sebastian, Spain. FAU - Aurrekoetxea, Juan J AU - Aurrekoetxea JJ AD - Public Health Department, Basque Government, Vitoria-Gasteiz, Spain. FAU - Davila, Fernando AU - Davila F AD - Department of Orthopedic Surgery, Clinica Pakea-Mutualia, San Sebastian, Spain. LA - eng PT - Journal Article PT - Randomized Controlled Trial DEP - 20210527 PL - United States TA - J Clin Ultrasound JT - Journal of clinical ultrasound : JCU JID - 0401663 SB - IM MH - *Carpal Tunnel Syndrome/diagnostic imaging/surgery MH - Hand Strength MH - Humans MH - Surveys and Questionnaires MH - Treatment Outcome MH - Ultrasonography MH - Ultrasonography, Interventional OTO - NOTNLM OT - carpal tunnel syndrome OT - hand OT - minimally invasive surgical procedures OT - musculoskeletal ultrasonography OT - nerves EDAT- 2021/05/29 06:00 MHDA- 2021/08/20 06:00 CRDT- 2021/05/28 07:41 PHST- 2021/04/20 00:00 [revised] PHST- 2020/05/29 00:00 [received] PHST- 2021/05/03 00:00 [accepted] PHST- 2021/05/29 06:00 [pubmed] PHST- 2021/08/20 06:00 [medline] PHST- 2021/05/28 07:41 [entrez] AID - 10.1002/jcu.23019 [doi] PST - ppublish SO - J Clin Ultrasound. 2021 Sep;49(7):693-703. doi: 10.1002/jcu.23019. Epub 2021 May 27.