PMID- 34051045 OWN - NLM STAT- MEDLINE DCOM- 20220407 LR - 20220407 IS - 1522-726X (Electronic) IS - 1522-1946 (Linking) VI - 99 IP - 2 DP - 2022 Feb TI - Intravascular lithotripsy for treatment of calcific coronary lesions in ST elevation myocardial infarction. PG - 322-328 LID - 10.1002/ccd.29801 [doi] AB - AIMS: To describe the utility and safety of intravascular lithotripsy (IVL) in the setting of primary percutaneous coronary intervention (PCI) for ST elevation myocardial infarction (STEMI). METHODS AND RESULTS: We performed a retrospective analysis, across six UK sites of all patients in whom IVL was used for coronary calcium modification of the culprit lesion during primary PCI for STEMI. The 72 patients were included. IVL was used in de-novo culprit lesions in 57 (79%) of cases and culprit in-stent restenoses in 11 (15%) of cases. In four cases (6%) it was used in a newly deployed stent when this was under-expanded due to inadequate calcium modification. Of the 30 cases in which intracoronary imaging was available for stent analysis, the average stent expansion was 104%. Intra-procedural stent thrombosis occurred in one case (1%), and no-reflow in three cases (4%). The 30 day MACE rates were 18%. CONCLUSION: IVL appears to be feasible and safe for use in the treatment of calcific coronary artery disease in the setting of STEMI. CI - (c) 2021 The Authors. Catheterization and Cardiovascular Interventions published by Wiley Periodicals LLC. FAU - Cosgrove, Claudia AU - Cosgrove C AUID- ORCID: 0000-0003-1754-4680 AD - Department of Cardiology, St George's University Hospitals NHS Foundation Trust, London, UK. FAU - Hanratty, Colm G AU - Hanratty CG AD - Department of Cardiology, Mater Private Hospital, Dublin, UK. FAU - Hill, Jonathan M AU - Hill JM AD - Department of Cardiology, Royal Brompton and Harefield NHS Foundation Trust, London, UK. FAU - Mahadevan, Kalaivani AU - Mahadevan K AD - Department of Cardiology, Bristol Heart Institute, Bristol, UK. FAU - Mailey, Jonathan AU - Mailey J AUID- ORCID: 0000-0002-9013-5720 AD - Department of Cardiology, Belfast Health and Social Care Trust, Belfast, UK. FAU - McEntegart, Margaret AU - McEntegart M AUID- ORCID: 0000-0001-5135-3322 AD - Department of Cardiology, Golden Jubilee Hospital, Clydebank, UK. FAU - O'Kane, Peter AU - O'Kane P AD - Department of Cardiology, Royal Bournemouth Hospital, Bournemouth, UK. FAU - Sidik, Novalia AU - Sidik N AD - Department of Cardiology, Golden Jubilee Hospital, Clydebank, UK. FAU - Strange, Julian W AU - Strange JW AD - Department of Cardiology, Bristol Heart Institute, Bristol, UK. FAU - Walsh, Simon J AU - Walsh SJ AD - Department of Cardiology, Belfast Health and Social Care Trust, Belfast, UK. FAU - Wilson, Simon AU - Wilson S AUID- ORCID: 0000-0002-1999-5103 AD - Department of Cardiology, St George's University Hospitals NHS Foundation Trust, London, UK. FAU - Yeoh, Julian AU - Yeoh J AUID- ORCID: 0000-0003-4957-186X AD - Department of Cardiology, Kings College Hospital NHS Foundation Trust, London, UK. FAU - Spratt, James C AU - Spratt JC AUID- ORCID: 0000-0001-8719-4538 AD - Department of Cardiology, St George's University Hospitals NHS Foundation Trust, London, UK. LA - eng PT - Journal Article DEP - 20210529 PL - United States TA - Catheter Cardiovasc Interv JT - Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions JID - 100884139 SB - IM MH - Humans MH - *Lithotripsy/adverse effects/methods MH - *Percutaneous Coronary Intervention/adverse effects/methods MH - Retrospective Studies MH - *ST Elevation Myocardial Infarction/diagnostic imaging/therapy MH - Treatment Outcome MH - *Vascular Calcification/diagnostic imaging/therapy OTO - NOTNLM OT - ST elevation myocardial infarction OT - calcium OT - coronary artery disease OT - percutaneous coronary intervention EDAT- 2021/05/30 06:00 MHDA- 2022/04/08 06:00 CRDT- 2021/05/29 12:21 PHST- 2021/03/29 00:00 [revised] PHST- 2020/12/11 00:00 [received] PHST- 2021/05/17 00:00 [accepted] PHST- 2021/05/30 06:00 [pubmed] PHST- 2022/04/08 06:00 [medline] PHST- 2021/05/29 12:21 [entrez] AID - 10.1002/ccd.29801 [doi] PST - ppublish SO - Catheter Cardiovasc Interv. 2022 Feb;99(2):322-328. doi: 10.1002/ccd.29801. Epub 2021 May 29.