PMID- 34055430
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210601
IS  - 2090-6625 (Print)
IS  - 2090-6633 (Electronic)
VI  - 2021
DP  - 2021
TI  - Exacerbating Guillain-Barre Syndrome Eight Days after Vector-Based COVID-19 
      Vaccination.
PG  - 3619131
LID - 10.1155/2021/3619131 [doi]
LID - 3619131
AB  - Since the introduction of mRNA technology-based and vector-based COVID-19 
      vaccines, adverse reactions to these agents have been occasionally reported. 
      Exacerbation of Guillain-Barre syndrome (GBS) shortly after COVID-19 vaccination 
      has not been communicated. The patient is a 32-year-old male who developed 
      progressive sensory disturbances and muscle weakness 8 days after the first 
      dosage of a vector-based vaccine. Cerebrospinal fluid investigations revealed a 
      dissociation cyto-albuminque, and nerve conduction studies revealed 
      demyelination. Intravenous immunoglobulin (IVIG) exhibited only a marginal effect 
      for both sensory and motor deficits. The patient's history was moreover positive 
      for previous GBS with marked motor deficits 14 years earlier, which responded 
      favourably to IVIG leading to almost complete recovery within 9 months of 
      rehabilitation. Although apparently extremely rare, neurologists should remain 
      vigilant for a potential recurrence of GBS after vaccination with a vector-based 
      COVID-19 vaccine.
CI  - Copyright (c) 2021 Josef Finsterer.
FAU - Finsterer, Josef
AU  - Finsterer J
AUID- ORCID: 0000-0003-2839-7305
AD  - Klinik Landstrasse, Messerli Institute, Postfach 20, Vienna, Austria.
LA  - eng
PT  - Case Reports
DEP - 20210508
PL  - Egypt
TA  - Case Rep Infect Dis
JT  - Case reports in infectious diseases
JID - 101573243
PMC - PMC8123983
COIS- The authors declare no conflicts of interest.
EDAT- 2021/06/01 06:00
MHDA- 2021/06/01 06:01
PMCR- 2021/05/08
CRDT- 2021/05/31 06:14
PHST- 2021/04/06 00:00 [received]
PHST- 2021/04/23 00:00 [revised]
PHST- 2021/04/28 00:00 [accepted]
PHST- 2021/05/31 06:14 [entrez]
PHST- 2021/06/01 06:00 [pubmed]
PHST- 2021/06/01 06:01 [medline]
PHST- 2021/05/08 00:00 [pmc-release]
AID - 10.1155/2021/3619131 [doi]
PST - epublish
SO  - Case Rep Infect Dis. 2021 May 8;2021:3619131. doi: 10.1155/2021/3619131. 
      eCollection 2021.