PMID- 34056180
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210601
IS  - 2470-1343 (Electronic)
IS  - 2470-1343 (Linking)
VI  - 6
IP  - 15
DP  - 2021 Apr 20
TI  - Trace Analysis of Fenbutatin Oxide in Soil and Plant- and Animal-Derived Foods 
      Using Modified QuEChERS Coupled with HPLC-MS/MS.
PG  - 10260-10265
LID - 10.1021/acsomega.1c00593 [doi]
AB  - A modified QuEChERS method in combination with high-performance liquid 
      chromatography-tandem mass spectrometry (HPLC-MS/MS) was first developed for the 
      determination of fenbutatin oxide in six types of samples (soil, tobacco, rice, 
      milk, pork liver, and pork). Fenbutatin oxide was extracted with acetonitrile 
      containing 1% formic acid (v/v) and purified by dispersive solid-phase extraction 
      using primary secondary amine (PSA) and quantitatively analyzed by HPLC-MS/MS. In 
      the range of 0.005-1 mg/kg, a good linear relationship exists between the 
      concentration of fenbutatin oxide and the peak area, giving a coefficient of 
      determination (R (2)) of >0.99. The recoveries of fenbutatin oxide at three 
      spiked levels were 79.04-97.12% with the relative standard deviations (RSDs) of 
      3.30-10.96%, and the limit of quantification (LOQ) was 0.007 mg/kg. In addition, 
      the developed method is consistent with the reference method (R (2) = 0.9896, n = 
      40). The method is demonstrated to be convenient and reliable for the routine 
      monitoring of fenbutatin oxide in soil and plant- and animal-derived foods.
CI  - (c) 2021 The Authors. Published by American Chemical Society.
FAU - Lin, Zhihui
AU  - Lin Z
AD  - Sanming Tobacco Company of Fujian Province, Sanming 365000, China.
FAU - Lin, Yingnan
AU  - Lin Y
AD  - Chinese Academy of Agricultural Sciences Institute of Tobacco Research, Qingdao 
      266101, China.
FAU - Lin, Jianqi
AU  - Lin J
AD  - Sanming Tobacco Company of Fujian Province, Sanming 365000, China.
FAU - Zhang, Yizhi
AU  - Zhang Y
AUID- ORCID: 0000-0002-3041-6512
AD  - Chinese Academy of Agricultural Sciences Institute of Tobacco Research, Qingdao 
      266101, China.
FAU - Fang, Song
AU  - Fang S
AUID- ORCID: 0000-0002-7187-2565
AD  - Chinese Academy of Agricultural Sciences Institute of Tobacco Research, Qingdao 
      266101, China.
LA  - eng
PT  - Journal Article
DEP - 20210406
PL  - United States
TA  - ACS Omega
JT  - ACS omega
JID - 101691658
PMC - PMC8153780
COIS- The authors declare no competing financial interest.
EDAT- 2021/06/01 06:00
MHDA- 2021/06/01 06:01
PMCR- 2021/04/06
CRDT- 2021/05/31 06:22
PHST- 2021/02/01 00:00 [received]
PHST- 2021/03/25 00:00 [accepted]
PHST- 2021/05/31 06:22 [entrez]
PHST- 2021/06/01 06:00 [pubmed]
PHST- 2021/06/01 06:01 [medline]
PHST- 2021/04/06 00:00 [pmc-release]
AID - 10.1021/acsomega.1c00593 [doi]
PST - epublish
SO  - ACS Omega. 2021 Apr 6;6(15):10260-10265. doi: 10.1021/acsomega.1c00593. 
      eCollection 2021 Apr 20.