PMID- 34058301
OWN - NLM
STAT- MEDLINE
DCOM- 20211005
LR  - 20211005
IS  - 1872-8227 (Electronic)
IS  - 0168-8227 (Linking)
VI  - 177
DP  - 2021 Jul
TI  - Predictive value of the SYNTAX score for diabetic retinopathy in stable coronary 
      artery disease patients with a concomitant type 2 diabetes mellitus.
PG  - 108875
LID - S0168-8227(21)00234-5 [pii]
LID - 10.1016/j.diabres.2021.108875 [doi]
AB  - AIMS: Diabetic retinopathy (DR) is a serious complication of type 2 diabetes 
      mellitus (T2DM) and is the most common cause of impaired vision for adults. DR is 
      related to a number of risk factors. The aim of this study was to investigate the 
      relationship between burden of coronary artery disease assessed by Syntax Score 
      (SS) and DR in T2DM. METHODS: A total of 96 T2DM patients undergoing coronary 
      angiography were prospectively included in the study. Presence and severity of DR 
      were assessed by ocular fundus examination. DR was graded as no apparent 
      retinopathy (NDR), non-proliferative (NPDR), and proliferative DR (PDR). The SS 
      for each patient was calculated. RESULTS: The mean age was 58.0 +/- 8.2 years. SS 
      gradually increased from NDR group to PDR group. The median (IQR) value of SS was 
      10 (5-16) in patients with NDR, 22.8 (17-35.8) in those with NPDR, and 35.5 
      (28-37) in those with PDR (p < 0.001). On multivariate analysis SS [odds ratio 
      (OR) 1.145, p = 0.001] and duration of diabetes (OR 1.753, p = 0.031) were 
      independent factors for DR. CONCLUSIONS: The SS is independently associated with 
      the occurrence of DR in T2DM. Ophthalmologists and cardiologists must cooperate 
      when evaluating patients with DM because of possible complications.
CI  - Copyright (c) 2021 Elsevier B.V. All rights reserved.
FAU - Kurtul, Bengi Ece
AU  - Kurtul BE
AD  - Hatay Mustafa Kemal University, Tayfur Ata Sokmen Faculty of Medicine, Department 
      of Ophthalmology, Hatay, Turkey. Electronic address: becekurtul@yahoo.com.
FAU - Kurtul, Alparslan
AU  - Kurtul A
AD  - Hatay Mustafa Kemal University, Tayfur Ata Sokmen Faculty of Medicine, Department 
      of Cardiology, Hatay, Turkey.
FAU - Yalcin, Fatih
AU  - Yalcin F
AD  - Hatay Mustafa Kemal University, Tayfur Ata Sokmen Faculty of Medicine, Department 
      of Cardiology, Hatay, Turkey.
LA  - eng
PT  - Journal Article
DEP - 20210529
PL  - Ireland
TA  - Diabetes Res Clin Pract
JT  - Diabetes research and clinical practice
JID - 8508335
SB  - IM
MH  - Aged
MH  - *Coronary Artery Disease/diagnostic imaging/epidemiology/etiology
MH  - *Diabetes Mellitus, Type 2/complications
MH  - *Diabetic Retinopathy/diagnostic imaging/epidemiology
MH  - Humans
MH  - Middle Aged
MH  - Odds Ratio
MH  - Risk Factors
OTO - NOTNLM
OT  - Diabetes mellitus
OT  - Diabetic retinopathy
OT  - Syntax score
COIS- Declaration of Competing Interest The authors declare that they have no known 
      competing financial interests or personal relationships that could have appeared 
      to influence the work reported in this paper.
EDAT- 2021/06/01 06:00
MHDA- 2021/10/06 06:00
CRDT- 2021/05/31 20:12
PHST- 2020/11/10 00:00 [received]
PHST- 2021/03/13 00:00 [revised]
PHST- 2021/05/26 00:00 [accepted]
PHST- 2021/06/01 06:00 [pubmed]
PHST- 2021/10/06 06:00 [medline]
PHST- 2021/05/31 20:12 [entrez]
AID - S0168-8227(21)00234-5 [pii]
AID - 10.1016/j.diabres.2021.108875 [doi]
PST - ppublish
SO  - Diabetes Res Clin Pract. 2021 Jul;177:108875. doi: 10.1016/j.diabres.2021.108875. 
      Epub 2021 May 29.