PMID- 34064150
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210615
IS  - 2077-0383 (Print)
IS  - 2077-0383 (Electronic)
IS  - 2077-0383 (Linking)
VI  - 10
IP  - 11
DP  - 2021 May 21
TI  - Repeatability of Spectral Domain Optical Coherence Tomography Measurements of 
      Bruch's Membrane Opening-Minimum Rim Width in Epiretinal Membrane Patients with 
      Peripapillary Involvement.
LID - 10.3390/jcm10112240 [doi]
LID - 2240
AB  - The Bruch's membrane opening-minimum rim width (BMO-MRW) is a recently introduced 
      parameter of the neuroretinal rim. We analyzed the repeatability of 
      spectral-domain optical coherence tomography (SD-OCT) measurements of BMO-MRW in 
      epiretinal membrane (ERM) patients with peripapillary involvement, since the 
      surface around the optic disc is distorted in such patients. BMO-MRW and retinal 
      nerve fiber layer (RNFL) thickness measurements were performed using SD-OCT in 
      prospectively enrolled ERM patients and age-matched healthy control individuals. 
      After two consecutive measurements with a 5 min interval, repeatability was 
      analyzed using the intraclass correlation coefficient (ICC), repeatability 
      coefficient (RC), and coefficient of variation (CV). Fifty-two eyes of 52 ERM 
      patients and 62 eyes of 62 healthy controls were included in the study. The ICCs 
      of the mean BMO-MRW/RNFL thickness measurements were 0.999/0.985 in ERM eyes and 
      0.999/0.999 in normal eyes, respectively. The RC values of mean BMO-MRW/RNFL 
      thickness measurements were 9.0/6.25 mum in ERM eyes and 4.61/0.92 mum in normal 
      eyes, respectively. The CV values were 0.91% and 1.45% for BMO-MRW and RNFL 
      thickness in ERM eyes, and 0.63% and 0.33% in normal eyes, respectively. In ERM 
      eyes, the RC, CV of average BMO-MRW were 1.9 and 1.4 times greater than those of 
      normal eyes, but 6.8 and 4.4 times greater for average RNFL thickness. BMO-MRW 
      and RNFL thickness showed good repeatability in the diseased eyes with 
      peripapillary involvement and healthy control eyes. Based on the ICC, RC, and CV 
      values, the repeatability of BMO-MRW measurements in peripapillary membrane 
      patients was better than that of RNFL thickness.
FAU - Nam, Ki Yup
AU  - Nam KY
AUID- ORCID: 0000-0002-3602-8422
AD  - Department of Ophthalmology, Chungnam National University Sejong Hospital, Sejong 
      30099, Korea.
AD  - Department of Ophthalmology, College of Medicine, Chungnam National University, 
      Daejeon 35015, Korea.
FAU - Kim, Bum Jun
AU  - Kim BJ
AD  - Department of Ophthalmology, Gyeongsang National University Changwon Hospital, 
      Changwon 51472, Korea.
FAU - Lee, Woo Hyuk
AU  - Lee WH
AUID- ORCID: 0000-0003-3133-2430
AD  - Department of Ophthalmology, Gyeongsang National University Changwon Hospital, 
      Changwon 51472, Korea.
FAU - Han, Yong Seop
AU  - Han YS
AD  - Department of Ophthalmology, Gyeongsang National University Changwon Hospital, 
      Changwon 51472, Korea.
AD  - Department of Ophthalmology, College of Medicine, Gyeongsang National University, 
      Jinju 52828, Korea.
AD  - Gyeongsang Institute of Health Sciences, Gyeongsang National University, Jinju 
      52828, Korea.
LA  - eng
PT  - Journal Article
DEP - 20210521
PL  - Switzerland
TA  - J Clin Med
JT  - Journal of clinical medicine
JID - 101606588
PMC - PMC8196710
OTO - NOTNLM
OT  - Bruch's membrane opening-minimum rim width
OT  - epiretinal membrane
OT  - repeatability
OT  - retinal nerve fiber layer
COIS- The authors declare no conflict of interest.
EDAT- 2021/06/03 06:00
MHDA- 2021/06/03 06:01
PMCR- 2021/05/21
CRDT- 2021/06/02 01:08
PHST- 2021/03/24 00:00 [received]
PHST- 2021/05/08 00:00 [revised]
PHST- 2021/05/17 00:00 [accepted]
PHST- 2021/06/02 01:08 [entrez]
PHST- 2021/06/03 06:00 [pubmed]
PHST- 2021/06/03 06:01 [medline]
PHST- 2021/05/21 00:00 [pmc-release]
AID - jcm10112240 [pii]
AID - jcm-10-02240 [pii]
AID - 10.3390/jcm10112240 [doi]
PST - epublish
SO  - J Clin Med. 2021 May 21;10(11):2240. doi: 10.3390/jcm10112240.