PMID- 34065994
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210605
IS  - 2073-4360 (Electronic)
IS  - 2073-4360 (Linking)
VI  - 13
IP  - 10
DP  - 2021 May 12
TI  - Preparation of Polyetherimide Nanoparticles by a Droplet Evaporation-Assisted 
      Thermally Induced Phase-Separation Method.
LID - 10.3390/polym13101548 [doi]
LID - 1548
AB  - The droplet evaporation effect on the preparation of polyetherimide (PEI) 
      nanoparticles by thermally induced phase separation (TIPS) was studied. PEI 
      nanoparticles were prepared in two routes. In route I, the droplet evaporation 
      process was carried out after TIPS. In route II, the droplet evaporation and TIPS 
      processes were carried out simultaneously. The surface tension and shape 
      parameters of samples were measured via a drop shape analyzer. The Z-average 
      particle diameter of PEI nanoparticles in the PEI/dimethyl sulfoxide solution 
      (DMSO) suspension at different time points was tested by dynamic light 
      scattering, the data from which was used to determine the TIPS time of the 
      PEI/DMSO solution. The natural properties of the products from both routes were 
      studied by optical microscope, scanning electron microscope and transmission 
      electron microscope. The results show that PEI nanoparticles prepared from route 
      II are much smaller and more uniform than that prepared from route I. Circulation 
      flows in the droplet evaporation were indirectly proved to suppress the growth of 
      particles. At 30  degrees C, PEI solid nanoparticles with 193 nm average particle size, 
      good uniformity, good separation and good roundness were obtained. Route I is 
      less sensitive to temperature than route II. Samples in route I were still the 
      accumulations of micro and nanoparticles until 40  degrees C instead of 30  degrees C in route 
      II, although the particle size distribution was not uniform. In addition, a film 
      structure would appear instead of particles when the evaporation temperature 
      exceeds a certain value in both routes. This work will contribute to the 
      preparation of polymer nanoparticles with small and uniform particle size by TIPS 
      process from preformed polymers.
FAU - Zhu, Peng
AU  - Zhu P
AUID- ORCID: 0000-0001-7345-2073
AD  - College of Textile Science and Engineering (International Institute of Silk), 
      Zhejiang Sci-Tech University, Hangzhou 310018, China.
FAU - Zhang, Huapeng
AU  - Zhang H
AD  - College of Textile Science and Engineering (International Institute of Silk), 
      Zhejiang Sci-Tech University, Hangzhou 310018, China.
FAU - Lu, Hongwei
AU  - Lu H
AD  - College of Textile Science and Engineering (International Institute of Silk), 
      Zhejiang Sci-Tech University, Hangzhou 310018, China.
LA  - eng
GR  - 18012278-Y/Research Initiation Fund Project from Zhejiang Sci-Tech University/
GR  - LQ20E030001/Natural Science Foundation of Zhejiang province, China/
PT  - Journal Article
DEP - 20210512
PL  - Switzerland
TA  - Polymers (Basel)
JT  - Polymers
JID - 101545357
PMC - PMC8150268
OTO - NOTNLM
OT  - coffee ring effect
OT  - droplet evaporation
OT  - evaporation kinetic
OT  - polyetherimide
OT  - polymer nanoparticle
OT  - thermally induced phase separation
COIS- The authors declare no conflict of interest.
EDAT- 2021/06/03 06:00
MHDA- 2021/06/03 06:01
PMCR- 2021/05/12
CRDT- 2021/06/02 01:14
PHST- 2021/04/20 00:00 [received]
PHST- 2021/05/07 00:00 [revised]
PHST- 2021/05/08 00:00 [accepted]
PHST- 2021/06/02 01:14 [entrez]
PHST- 2021/06/03 06:00 [pubmed]
PHST- 2021/06/03 06:01 [medline]
PHST- 2021/05/12 00:00 [pmc-release]
AID - polym13101548 [pii]
AID - polymers-13-01548 [pii]
AID - 10.3390/polym13101548 [doi]
PST - epublish
SO  - Polymers (Basel). 2021 May 12;13(10):1548. doi: 10.3390/polym13101548.