PMID- 34067255
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210626
IS  - 1099-4300 (Electronic)
IS  - 1099-4300 (Linking)
VI  - 23
IP  - 6
DP  - 2021 May 22
TI  - Influence of Ectopic Beats on Heart Rate Variability Analysis.
LID - 10.3390/e23060648 [doi]
LID - 648
AB  - The analysis of heart rate variability (HRV) plays a dominant role in the study 
      of physiological signal variability. HRV reflects the information of the 
      adjustment of sympathetic and parasympathetic nerves on the cardiovascular system 
      and, thus, is widely used to evaluate the functional status of the cardiovascular 
      system. Ectopic beats may affect the analysis of HRV. However, the quantitative 
      relationship between the burden of ectopic beats and HRV indices, including 
      entropy measures, has not yet been investigated in depth. In this work, we 
      analyzed the effects of different numbers of ectopic beats on several widely 
      accepted HRV parameters in time-domain (SDNN), frequency-domain (LF/HF), as well 
      as non-linear features (SampEn and Pt-SampEn (physical threshold-based SampEn)). 
      The results showed that all four indices were influenced by ectopic beats, and 
      the degree of influence was roughly increased with the increase of the number of 
      ectopic beats. Ectopic beats had the greatest impact on the frequency domain 
      index LF/HF, whereas the Pt-SampEn was minimally accepted by ectopic beats. These 
      results also indicated that, compared with the other three indices, Pt-SampEn had 
      better robustness for ectopic beats.
FAU - Zhao, Lina
AU  - Zhao L
AD  - The State Key Laboratory of Bioelectronics, School of Instrument Science and 
      Engineering, Southeast University, Nanjing 210096, China.
FAU - Li, Peng
AU  - Li P
AUID- ORCID: 0000-0002-4684-4909
AD  - Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Harvard 
      Medical School, Boston, MA 02115, USA.
FAU - Li, Jianqing
AU  - Li J
AD  - The State Key Laboratory of Bioelectronics, School of Instrument Science and 
      Engineering, Southeast University, Nanjing 210096, China.
FAU - Liu, Chengyu
AU  - Liu C
AD  - The State Key Laboratory of Bioelectronics, School of Instrument Science and 
      Engineering, Southeast University, Nanjing 210096, China.
LA  - eng
GR  - 81871444 and 62071241/National Natural Science Foundation of China/
PT  - Journal Article
DEP - 20210522
PL  - Switzerland
TA  - Entropy (Basel)
JT  - Entropy (Basel, Switzerland)
JID - 101243874
PMC - PMC8224602
OTO - NOTNLM
OT  - congestive heart failure
OT  - electrocardiogram
OT  - heart rate variability
OT  - sample entropy
COIS- The authors declare no conflict of interest.
EDAT- 2021/06/03 06:00
MHDA- 2021/06/03 06:01
PMCR- 2021/05/22
CRDT- 2021/06/02 01:18
PHST- 2021/04/05 00:00 [received]
PHST- 2021/05/15 00:00 [revised]
PHST- 2021/05/19 00:00 [accepted]
PHST- 2021/06/02 01:18 [entrez]
PHST- 2021/06/03 06:00 [pubmed]
PHST- 2021/06/03 06:01 [medline]
PHST- 2021/05/22 00:00 [pmc-release]
AID - e23060648 [pii]
AID - entropy-23-00648 [pii]
AID - 10.3390/e23060648 [doi]
PST - epublish
SO  - Entropy (Basel). 2021 May 22;23(6):648. doi: 10.3390/e23060648.