PMID- 34068380
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240402
IS  - 2077-0383 (Print)
IS  - 2077-0383 (Electronic)
IS  - 2077-0383 (Linking)
VI  - 10
IP  - 10
DP  - 2021 May 13
TI  - Antidiabetic and Other Therapies Used in Subjects with Diabetes and Chronic 
      Kidney Disease in a Hospital-Based Clinic Population in Greece.
LID - 10.3390/jcm10102104 [doi]
LID - 2104
AB  - (1) Background: Type 2 diabetes mellitus (T2DM) is the main cause of chronic 
      kidney disease (CKD). In Greece, in a population from hospital-based diabetes 
      clinics (n = 1759), the overall prevalence of diabetic chronic kidney disease 
      (DCKD) was 45% including mild, moderate, and severe CKD. The aim of this study 
      was to describe and analyze how T2DM patients with mild-to-severe CKD are managed 
      by diabetologists in Greece and assess the achievement rates in glycemic, blood 
      pressure and low-density lipoprotein-cholesterol (LDL-C) control. (2) Methods: 
      This cross-sectional multicenter study took place from June 2015 to March 2016 
      and collected data from diabetes centers in public hospitals all over Greece. (3) 
      Results: With regard to the anti-diabetes treatment, most participants were on 
      metformin, DPP-4 (Dipeptidyl Peptidase-4 inhibitors) inhibitors and insulin. 
      Angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers were 
      the most prescribed medications for hypertension. For the management of 
      dyslipidemia, most participants were on statins. For patients with DCKD, the 
      levels of HbA1c, blood pressure and LDL-C were 7.2%, 137.7/76.9 mmHg and 95.9 
      mg/dL, respectively (mean values). (4) Conclusions: The outcomes of this study 
      suggest that management of DCKD can be further improved and should be enhanced. 
      These results may contribute to the whole health care system in Greece. In 
      addition, the better understanding of therapeutic strategies used by 
      diabetologists treating these patients offers educational benefits to primary 
      care physicians, which can result in an overall more successful and efficient 
      management of subjects with T2DM and DCKD.
FAU - Migdalis, Ilias N
AU  - Migdalis IN
AD  - Second Medical Department and Diabetes Centre, NIMTS Hospital, 11521 Athens, 
      Greece.
FAU - Papanas, Nikolaos
AU  - Papanas N
AD  - Second Department of Internal Medicine and Diabetes Centre, University Hospital 
      of Alexandroupolis, Democritus University of Thrace, 68132 Alexandroupolis, 
      Greece.
FAU - Ioannidis, Ioannis M
AU  - Ioannidis IM
AD  - First Department of Internal Medicine and Diabetes Centre, General Hospital of 
      Nea Ionia Konstantopoulio-Patision, 14233 Athens, Greece.
FAU - Sotiropoulos, Alexios E
AU  - Sotiropoulos AE
AD  - Third Medical Department and Diabetes Centre, Hospital of Nikaia, 18454 Piraeus, 
      Greece.
FAU - Raptis, Athanasios E
AU  - Raptis AE
AD  - Second Department of Internal Medicine, Attikon University Hospital, Medical 
      School, National and Kapodistrian University of Athens, 12462 Athens, Greece.
FAU - Dimitriadis, George D
AU  - Dimitriadis GD
AUID- ORCID: 0000-0002-0315-9936
AD  - Second Department of Internal Medicine, Attikon University Hospital, Medical 
      School, National and Kapodistrian University of Athens, 12462 Athens, Greece.
FAU - On Behalf Of The Hellenic Diabetic Nephropathy Study Hdns
AU  - On Behalf Of The Hellenic Diabetic Nephropathy Study Hdns
LA  - eng
PT  - Journal Article
DEP - 20210513
PL  - Switzerland
TA  - J Clin Med
JT  - Journal of clinical medicine
JID - 101606588
PMC - PMC8153603
OTO - NOTNLM
OT  - diabetes mellitus
OT  - diabetic chronic kidney disease
OT  - diabetic nephropathy
COIS- The authors declare no conflict of interest.
EDAT- 2021/06/03 06:00
MHDA- 2021/06/03 06:01
PMCR- 2021/05/13
CRDT- 2021/06/02 01:22
PHST- 2021/03/17 00:00 [received]
PHST- 2021/05/07 00:00 [revised]
PHST- 2021/05/10 00:00 [accepted]
PHST- 2021/06/02 01:22 [entrez]
PHST- 2021/06/03 06:00 [pubmed]
PHST- 2021/06/03 06:01 [medline]
PHST- 2021/05/13 00:00 [pmc-release]
AID - jcm10102104 [pii]
AID - jcm-10-02104 [pii]
AID - 10.3390/jcm10102104 [doi]
PST - epublish
SO  - J Clin Med. 2021 May 13;10(10):2104. doi: 10.3390/jcm10102104.