PMID- 34070362
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210714
IS  - 2218-1989 (Print)
IS  - 2218-1989 (Electronic)
IS  - 2218-1989 (Linking)
VI  - 11
IP  - 6
DP  - 2021 May 25
TI  - Potential of Beetroot and Blackcurrant Compounds to Improve Metabolic Syndrome 
      Risk Factors.
LID - 10.3390/metabo11060338 [doi]
LID - 338
AB  - Metabolic syndrome (MetS) is a group of metabolic abnormalities, which together 
      lead to increased risk of coronary heart disease (CHD) and type 2 diabetes 
      mellitus (T2DM), as well as reduced quality of life. Dietary nitrate, betalains 
      and anthocyanins may improve risk factors for MetS and reduce the risk of 
      development of CHD and T2DM. Beetroot is a rich source of dietary nitrate, and 
      anthocyanins are present in high concentrations in blackcurrants. This narrative 
      review considers the efficacy of beetroot and blackcurrant compounds as potential 
      agents to improve MetS risk factors, which could lead to decreased risk of CHD 
      and T2DM. Further research is needed to establish the mechanisms through which 
      these outcomes may occur, and chronic supplementation studies in humans may 
      corroborate promising findings from animal models and acute human trials.
FAU - Haswell, Cameron
AU  - Haswell C
AD  - School of Health Sciences, Massey University, Auckland 0745, New Zealand.
FAU - Ali, Ajmol
AU  - Ali A
AUID- ORCID: 0000-0002-6093-1435
AD  - School of Sport, Exercise and Nutrition, Massey University, Auckland 0745, New 
      Zealand.
AD  - Centre for Metabolic Health Research, Massey University, Auckland 0745, New 
      Zealand.
FAU - Page, Rachel
AU  - Page R
AUID- ORCID: 0000-0002-5971-4097
AD  - School of Health Sciences, Massey University, Wellington 6140, New Zealand.
AD  - Centre for Metabolic Health Research, Massey University, Wellington 6140, New 
      Zealand.
FAU - Hurst, Roger
AU  - Hurst R
AUID- ORCID: 0000-0002-4097-1368
AD  - Food Innovation Portfolio, The New Zealand Institute for Plant & Food Research 
      Ltd., Private Bag 11600, Palmerston North 4442, New Zealand.
FAU - Rutherfurd-Markwick, Kay
AU  - Rutherfurd-Markwick K
AUID- ORCID: 0000-0002-8815-3786
AD  - School of Health Sciences, Massey University, Auckland 0745, New Zealand.
AD  - Centre for Metabolic Health Research, Massey University, Auckland 0745, New 
      Zealand.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20210525
PL  - Switzerland
TA  - Metabolites
JT  - Metabolites
JID - 101578790
PMC - PMC8228969
OTO - NOTNLM
OT  - anthocyanins
OT  - betalains
OT  - diabetes
OT  - dietary nitrate
OT  - dyslipidemia
OT  - glucose control
OT  - hyperglycemia
OT  - hypertension
COIS- Hurst has dual associations with commercial organizations that may benefit 
      financially from the sale of products made from New Zealand blackcurrants: as 
      Principal Scientist for the New Zealand Institute for Plant and Food Research 
      Limited: and as Chief Science Advisor for 2before Performance Nutrition Limited. 
      These associations did not influence the representation or interpretation of 
      reported data and research findings.
EDAT- 2021/06/03 06:00
MHDA- 2021/06/03 06:01
PMCR- 2021/05/25
CRDT- 2021/06/02 01:28
PHST- 2021/04/29 00:00 [received]
PHST- 2021/05/20 00:00 [revised]
PHST- 2021/05/20 00:00 [accepted]
PHST- 2021/06/02 01:28 [entrez]
PHST- 2021/06/03 06:00 [pubmed]
PHST- 2021/06/03 06:01 [medline]
PHST- 2021/05/25 00:00 [pmc-release]
AID - metabo11060338 [pii]
AID - metabolites-11-00338 [pii]
AID - 10.3390/metabo11060338 [doi]
PST - epublish
SO  - Metabolites. 2021 May 25;11(6):338. doi: 10.3390/metabo11060338.