PMID- 34071359
OWN - NLM
STAT- MEDLINE
DCOM- 20220114
LR  - 20230920
IS  - 2076-3271 (Electronic)
IS  - 2076-3271 (Linking)
VI  - 9
IP  - 2
DP  - 2021 May 28
TI  - Expert Group Recommendations on the Effective Use of Bolus Insulin in the 
      Management of Type 2 Diabetes Mellitus.
LID - 10.3390/medsci9020038 [doi]
LID - 38
AB  - Evidence suggests a major contribution of postprandial glucose (PPG) excursions 
      to the increased risk of micro- and macro-vascular complications in individuals 
      with type 2 diabetes mellitus (T2DM). Administration of bolus insulin remains a 
      very effective therapeutic option for PPG control. The aim of this expert group 
      recommendation document was to provide practical and easy-to-execute guidelines 
      for physicians on the appropriate use of bolus insulin in the management of T2DM. 
      A panel of key opinion leaders from India reviewed and discussed the available 
      clinical evidence and guideline recommendations on the following topics: (1) 
      optimum control of PPG; (2) choice of bolus insulin; and (3) special situations 
      and practical considerations. The expert panel critically analyzed the current 
      literature and clinical practice guidelines and factored their rich clinical 
      experience to develop a set of nine expert group recommendations for the 
      effective use of bolus insulin. These recommendations will not only result in a 
      more evidence-based application of bolus insulin in the clinical setting but also 
      trigger further research and provide a valuable base for the development of 
      future guidelines on the use of bolus insulin in the management of individuals 
      with T2DM.
FAU - Chawla, Rajeev
AU  - Chawla R
AD  - Department of Diabetology, North Delhi Diabetes Centre, 180, Jai Apartments, Sec 
      9, Rohini 110085, India.
FAU - Mukherjee, Jagat Jyoti
AU  - Mukherjee JJ
AD  - Division of Endocrinology, Department of Medicine, Apollo Gleneagles Hospitals, 
      58, Canal Circular Road, Kolkata 700054, India.
FAU - Chawla, Manoj
AU  - Chawla M
AD  - Lina Diabetes Care and Mumbai Diabetes Research Centre, 704, Cosmos Plaza, Opp. 
      Indian Oil Nagar, J.P. Road, Andheri (W), Mumbai 400053, India.
FAU - Kanungo, Alok
AU  - Kanungo A
AD  - Department of Diabetology, Kanungo Institute of Diabetes Specialities Pvt. Ltd., 
      1120, Dumduma, Bhubaneswar 751019, India.
FAU - Shunmugavelu, Meenakshi Sundaram
AU  - Shunmugavelu MS
AD  - Department of Diabetology, Trichy Diabetes Speciality Centre (P) Ltd., B-37, 
      Sasthri Road, VII Cross East, Thillai Nagar, Trichy 620018, India.
FAU - Das, Ashok Kumar
AU  - Das AK
AD  - Department of Internal Medicine, Pondicherry Institute of Medical Sciences, 
      Kalathumettupathai, Ganapathichettikulam Village, No 20, Kalapet, Puducherry 
      6050146, India.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20210528
PL  - Switzerland
TA  - Med Sci (Basel)
JT  - Medical sciences (Basel, Switzerland)
JID - 101629322
RN  - 0 (Hypoglycemic Agents)
RN  - 0 (Insulin)
RN  - 0 (Insulin, Regular, Human)
MH  - *Diabetes Mellitus, Type 2/drug therapy
MH  - Humans
MH  - Hypoglycemic Agents
MH  - *Insulin
MH  - Insulin, Regular, Human
MH  - Postprandial Period
PMC - PMC8162981
OTO - NOTNLM
OT  - bolus insulin
OT  - expert group recommendations
OT  - type 2 diabetes mellitus
COIS- The authors have no conflicts of interest to report for this publication.
EDAT- 2021/06/03 06:00
MHDA- 2021/06/03 06:01
PMCR- 2021/05/28
CRDT- 2021/06/02 01:31
PHST- 2021/04/06 00:00 [received]
PHST- 2021/05/22 00:00 [revised]
PHST- 2021/05/25 00:00 [accepted]
PHST- 2021/06/02 01:31 [entrez]
PHST- 2021/06/03 06:00 [pubmed]
PHST- 2021/06/03 06:01 [medline]
PHST- 2021/05/28 00:00 [pmc-release]
AID - medsci9020038 [pii]
AID - medsci-09-00038 [pii]
AID - 10.3390/medsci9020038 [doi]
PST - epublish
SO  - Med Sci (Basel). 2021 May 28;9(2):38. doi: 10.3390/medsci9020038.