PMID- 34074376 OWN - NLM STAT- MEDLINE DCOM- 20210603 LR - 20210603 IS - 1000-8020 (Print) IS - 1000-8020 (Linking) VI - 50 IP - 3 DP - 2021 May TI - [Nutrition status of pregnant women and lactating mothers in rural areas of four counties in Guizhou and Henan Provinces]. PG - 382-388 LID - 10.19813/j.cnki.weishengyanjiu.2021.03.006 [doi] AB - OBJECTIVE: To analyze the levels of serum ferritin(SF), transferrin receptor(sTfR), vitamin D(VD), folate(FOL), vitamin B_(12)(VB_(12)) and homocysteine(Hcy) of pregnant women and lactating mothers in rural areas, aiming to evaluate the nutritional status of pregnant women and lactating mothers. METHODS: By using a cluster sampling method, the subjects were the pregnant women at 10-20 weeks& apos; gestation and lactating mothers at 42+/-7 days& apos; postpartum who have been to the maternal and children health hospital in the county for examination from August 2019 to March 2020. SF, VD, VB_(12) and FOL concentrations were determined using the chemiluminescence assay. Hypersensitive C-reactive protein(hsCRP) and sTfR levels were determined using the immunoturbidimetry assay. Hcy levels were determined using the enzymatic assay. The rates of iron, vitamin D, folic acid, VB_(12) deficiency and hyperhomocysteinemia(HHcy) were calculated. RESULTS: There were 1050 pregnant women and 309 lactating mothers involved. The levels of ferritin and sTfR were 49. 6(47. 1-52. 3) ng/mL and 2. 51(2. 46-2. 56) mg/L for the pregnant women, and 51. 0(46. 6-55. 9) ng/mL and 3. 53(3. 40-3. 67) mg/L for the lactating mother, respectively. The prevalence of iron deficiency in lactating mothers was significantly higher than the pregnant women(33. 0% vs. 24. 7%). The levels of VD were 17. 0(16. 6-17. 4) ng/mL for pregnant women and 16. 7(16. 0-17. 4) ng/mL for lactating mothers. The prevalence of VD deficiency was 64. 5% and 68. 9%, respectively. The level of FOL for pregnant women was significantly higher than the lactating mothers(11. 3(10. 9-11. 7)vs. 5. 7(5. 3-6. 1) ng/mL). The levels of VB_(12) for pregnant women was significantly lower than the lactating mother(282. 7(276. 1-289. 5) vs. 437. 7(418. 7-457. 6) pg/mL). The levels of Hcy for pregnant women was significantly lower than the lactating mother(7. 1(7. 0-7. 3) vs. 10. 5(10. 0-10. 9) mumol/L). The prevalence of FOL deficiency, VB_(12) deficiency and HHcy were 5. 0%, 17. 2% and 5. 0% for pregnant women and 29. 8%, 2. 3% and 27. 8% for lactating mothers, which were significant different between pregnant women and lactating mothers(P& lt; 0. 05). Among the four nutrients including iron, VD, folate and VB_(12), 75. 8% of pregnant women were deficient in at least one nutrient and 28. 1% were deficient in at least two nutrients. 81. 9% of lactating mothers were deficient in at least one nutrient and 41. 4% were deficient in at least two nutrients. CONCLUSION: There were various degrees of nutrient deficiency. Iron deficiency rates were high and VD deficiency were severe in both pregnant women and lactating mothers. In addition, the rates of folate deficiency and HHcy were high in lactating mothers in rural areas. FAU - Wang, Lijuan AU - Wang L AD - National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Key Laboratory of Trace Element Nutrition of National Health Commission of the People's Republic of China, Beijing 100050, China. FAU - Chen, Di AU - Chen D AD - National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Key Laboratory of Trace Element Nutrition of National Health Commission of the People's Republic of China, Beijing 100050, China. FAU - Tang, Yanbin AU - Tang Y AD - National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Key Laboratory of Trace Element Nutrition of National Health Commission of the People's Republic of China, Beijing 100050, China. FAU - Sun, Jing AU - Sun J AD - National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Key Laboratory of Trace Element Nutrition of National Health Commission of the People's Republic of China, Beijing 100050, China. FAU - Huo, Junsheng AU - Huo J AD - National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Key Laboratory of Trace Element Nutrition of National Health Commission of the People's Republic of China, Beijing 100050, China. FAU - Huang, Jian AU - Huang J AD - National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Key Laboratory of Trace Element Nutrition of National Health Commission of the People's Republic of China, Beijing 100050, China. LA - chi PT - Journal Article PL - China TA - Wei Sheng Yan Jiu JT - Wei sheng yan jiu = Journal of hygiene research JID - 9426367 RN - 935E97BOY8 (Folic Acid) RN - P6YC3EG204 (Vitamin B 12) SB - IM MH - Child MH - Female MH - Folic Acid MH - Humans MH - Lactation MH - *Mothers MH - *Nutritional Status MH - Pregnancy MH - Pregnant Women MH - Vitamin B 12 OTO - NOTNLM OT - VB_(12) deficiency OT - VD deficiency OT - folate deficiency OT - hyperhomocysteinemia OT - iron deficiency OT - lactating mothers OT - pregnant women EDAT- 2021/06/03 06:00 MHDA- 2021/06/04 06:00 CRDT- 2021/06/02 05:41 PHST- 2021/06/02 05:41 [entrez] PHST- 2021/06/03 06:00 [pubmed] PHST- 2021/06/04 06:00 [medline] AID - 10.19813/j.cnki.weishengyanjiu.2021.03.006 [doi] PST - ppublish SO - Wei Sheng Yan Jiu. 2021 May;50(3):382-388. doi: 10.19813/j.cnki.weishengyanjiu.2021.03.006.