PMID- 34080696
OWN - NLM
STAT- MEDLINE
DCOM- 20220217
LR  - 20220217
IS  - 1540-8159 (Electronic)
IS  - 0147-8389 (Linking)
VI  - 44
IP  - 7
DP  - 2021 Jul
TI  - Brady-arrhythmias in patients with atrial fibrillation and heart failure of 
      reduced ejection fraction: is his-bundle pacing superior to biventricular 
      pacing？.
PG  - 1193-1199
LID - 10.1111/pace.14289 [doi]
AB  - OBJECTIVE: To investigate the efficacy and safety of His-bundle pacing (HBP) 
      compared with the traditional biventricular pacing (BVP) on patients with 
      brady-arrhythmias, who suffer from permanent atrial fibrillation (AF) and heart 
      failure with reduced ejection fraction (HFrEF). METHODS: All patients with 
      brady-arrhythmias, permanent AF and HFrEF were continuously enrolled from January 
      2017 to July 2019 and followed up for at least 12 months. The differences in QRS 
      duration (QRSd), New York Heart Association (NYHA) classification, left 
      ventricular ejection fraction (LVEF), tricuspid regurgitation grade, mitral 
      regurgitation grade, left ventricular end-diastolic diameter (LVEDD), and left 
      atrial size were compared. RESULTS: A total of 52 patients were enrolled: 37 
      patients were with HBP and 15 patients with BVP. There was no electrode 
      dislodged, perforation, infection or thrombosis during the follow-up of 
      18.12 +/- 4.45 months. The success rate for HBP implantation was 88.10%. The 
      capture threshold of his-bundle and the threshold of the left ventricular lead 
      remained stable during follow-up. LVEF increased to higher than 50% in 11 
      patients with HBP (29.73%). The NYHA classification (both p < .001), LVEF (both 
      p < .001) and LVEDD improved significantly during the follow-up in both groups. 
      NYHA (p = .030), LVEF (p = .013), and LVEDD (p = .003) improved in patients with 
      HBP compared with BVP. CONCLUSION: HBP was safe and more effective in improving 
      the cardiac function and remodeling in patients with brady-arrhythmias, permanent 
      AF and HFrEF compared with BVP.
CI  - (c) 2021 Wiley Periodicals LLC.
FAU - Ma, Pei-Pei
AU  - Ma PP
AUID- ORCID: 0000-0003-3579-8000
AD  - Department of Cardiology, The First Affiliated Hospital of Dalian Medical 
      University, Dalian, Liaoning, China.
FAU - Yang, Yi-Heng
AU  - Yang YH
AD  - Department of Cardiology, The First Affiliated Hospital of Dalian Medical 
      University, Dalian, Liaoning, China.
FAU - Dai, Bai-Ling
AU  - Dai BL
AD  - Department of Cardiology, The First Affiliated Hospital of Dalian Medical 
      University, Dalian, Liaoning, China.
FAU - Zhang, Rong-Feng
AU  - Zhang RF
AD  - Department of Cardiology, The First Affiliated Hospital of Dalian Medical 
      University, Dalian, Liaoning, China.
FAU - Wang, Nan
AU  - Wang N
AD  - Department of Cardiology, The First Affiliated Hospital of Dalian Medical 
      University, Dalian, Liaoning, China.
FAU - Li, Dan-Na
AU  - Li DN
AD  - Department of Cardiology, The First Affiliated Hospital of Dalian Medical 
      University, Dalian, Liaoning, China.
FAU - Yin, Xiao-Meng
AU  - Yin XM
AD  - Department of Cardiology, The First Affiliated Hospital of Dalian Medical 
      University, Dalian, Liaoning, China.
FAU - Gao, Lian-Jun
AU  - Gao LJ
AD  - Department of Cardiology, The First Affiliated Hospital of Dalian Medical 
      University, Dalian, Liaoning, China.
FAU - Xia, Yun-Long
AU  - Xia YL
AUID- ORCID: 0000-0003-4791-9666
AD  - Department of Cardiology, The First Affiliated Hospital of Dalian Medical 
      University, Dalian, Liaoning, China.
FAU - Yang, Yan-Zong
AU  - Yang YZ
AD  - Department of Cardiology, The First Affiliated Hospital of Dalian Medical 
      University, Dalian, Liaoning, China.
FAU - Dong, Ying-Xue
AU  - Dong YX
AD  - Department of Cardiology, The First Affiliated Hospital of Dalian Medical 
      University, Dalian, Liaoning, China.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20210616
PL  - United States
TA  - Pacing Clin Electrophysiol
JT  - Pacing and clinical electrophysiology : PACE
JID - 7803944
SB  - IM
CIN - Pacing Clin Electrophysiol. 2021 Sep;44(9):1481-1484. PMID: 34339056
MH  - Aged
MH  - Aged, 80 and over
MH  - Atrial Fibrillation/*complications/physiopathology
MH  - Bradycardia/*etiology/*therapy
MH  - Bundle of His/physiopathology
MH  - Cardiac Resynchronization Therapy/adverse effects/*methods
MH  - Female
MH  - Heart Failure/*complications/physiopathology
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Stroke Volume
MH  - Treatment Outcome
OTO - NOTNLM
OT  - atrial fibrillation
OT  - biventricular pacing
OT  - heart failure
OT  - his-bundle pacing
OT  - left bundle branch block
EDAT- 2021/06/04 06:00
MHDA- 2022/02/19 06:00
CRDT- 2021/06/03 08:49
PHST- 2021/04/19 00:00 [revised]
PHST- 2020/09/20 00:00 [received]
PHST- 2021/05/30 00:00 [accepted]
PHST- 2021/06/04 06:00 [pubmed]
PHST- 2022/02/19 06:00 [medline]
PHST- 2021/06/03 08:49 [entrez]
AID - 10.1111/pace.14289 [doi]
PST - ppublish
SO  - Pacing Clin Electrophysiol. 2021 Jul;44(7):1193-1199. doi: 10.1111/pace.14289. 
      Epub 2021 Jun 16.