PMID- 34082957
OWN - NLM
STAT- MEDLINE
DCOM- 20210607
LR  - 20210607
IS  - 1873-0191 (Electronic)
IS  - 0928-4931 (Linking)
VI  - 126
DP  - 2021 Jul
TI  - A Tagetes minuta based eco-benign synthesis of multifunctional Au/MgO 
      nanocomposite with enhanced photocatalytic, antibacterial and DPPH scavenging 
      activities.
PG  - 112146
LID - S0928-4931(21)00285-X [pii]
LID - 10.1016/j.msec.2021.112146 [doi]
AB  - In this research work, facile, economical and eco-benign experimental procedure 
      were adopted to synthesize Au/MgO nanocomposite with the help of Tagetes minuta 
      leaves extract. Phytochemicals present in the leaves of Tagetes minuta were 
      acting as reducing and stabilizing agents to avoid aggregation of nanomaterials 
      during the preparation of Au/MgO nanocomposite. The biologically synthesized 
      nanocomposite were systematically characterized by UV-vis spectroscopy, Scanning 
      electron microscope (SEM), X-ray diffraction (XRD), Fourier transform infrared 
      microscopy (FTIR), High resolution transmission electron microscopy (HRTEM), 
      Thermogravimetric analysis (TGA), dynamic light scattering (DLS) and elemental 
      mapping. UV-visible spectrum confirmed the presence of MgO and Au due to the 
      presence of two SPR peaks at 315 nm and 528 nm, respectively. Moreover, the 
      Au/MgO nanocomposite exhibited superior photocatalytic, antibacterial, hemolytic, 
      and antioxidant activities. Photocatalytic performance tests of Au/MgO 
      nanocomposite were- appraised by the rapid degradation of the methylene blue (MB) 
      under UV light illumination. More importantly, after four successive cycles of MB 
      degradation, the photocatalytic efficacy remained unchanged, which ensures the 
      stability of the Au/MgO nanocomposite. Furthermore, the antibacterial tests 
      showed that the advanced nanocomposite inhibited the growth of Escherichia coli, 
      Bacillus subtilis, and Staphylococcus aureus with zones of inhibition 18 (+/-0.3), 
      21 (+/-0.5), and 19 (+/-0.4) mm, respectively. The cytotoxicity study revealed that 
      Au/MgO nanocomposite is nontoxic to ordinary healthy RBCs. Interestingly, the 
      Au/MgO nanocomposite also possesses an excellent antioxidant activity, whereby 
      effectively scavenging 82% stable and harmful DPPH. Overall, the present study 
      concludes that eco-benign Au/MgO nanocomposite has excellent potential for the 
      remediation of bacterial pathogens and degradation of MB.
CI  - Copyright (c) 2021 Elsevier B.V. All rights reserved.
FAU - Khan, Afaq Ullah
AU  - Khan AU
AD  - State Key Laboratory of Chemical Resource Engineering, Beijing University of 
      Chemical Technology, Beijing 100029, China.
FAU - Khan, Qudrat Ullah
AU  - Khan QU
AD  - Key Laboratory of Optoelectronic Devices and Systems, Ministry of Education and 
      Guangdong Province, Collage of Physics and Optoelectronics Engineering, Shenzhen 
      University, Shenzhen 518060, China.
FAU - Tahir, Kamran
AU  - Tahir K
AD  - Institute of Chemical Sciences, Gomal University, D.I. Khan, KP, Pakistan.
FAU - Ullah, Sami
AU  - Ullah S
AD  - Department of Chemistry, COMSATS University Islamabad (CUI), Abbottabad campus, 
      22060, Pakistan.
FAU - Arooj, Aaranda
AU  - Arooj A
AD  - Department of Chemistry, COMSATS University Islamabad (CUI), Abbottabad campus, 
      22060, Pakistan.
FAU - Li, Baoshan
AU  - Li B
AD  - State Key Laboratory of Chemical Resource Engineering, Beijing University of 
      Chemical Technology, Beijing 100029, China. Electronic address: 
      bsli@mail.buct.edu.cn.
FAU - Rehman, Khalil Ur
AU  - Rehman KU
AD  - Institute of Chemical Sciences, Gomal University, D.I. Khan, KP, Pakistan.
FAU - Nazir, Sadia
AU  - Nazir S
AD  - Institute of Chemical Sciences, Gomal University, D.I. Khan, KP, Pakistan.
FAU - Khan, Mati Ullah
AU  - Khan MU
AD  - State Key Laboratory of Chemical Resource Engineering, Beijing University of 
      Chemical Technology, Beijing 100029, China.
FAU - Ullah, Irfan
AU  - Ullah I
AD  - State Key Laboratory of Chemical Resource Engineering, Beijing University of 
      Chemical Technology, Beijing 100029, China.
LA  - eng
PT  - Journal Article
DEP - 20210430
PL  - Netherlands
TA  - Mater Sci Eng C Mater Biol Appl
JT  - Materials science & engineering. C, Materials for biological applications
JID - 101484109
RN  - 0 (Anti-Bacterial Agents)
RN  - 3A3U0GI71G (Magnesium Oxide)
SB  - IM
MH  - Anti-Bacterial Agents/pharmacology
MH  - Catalysis
MH  - Magnesium Oxide
MH  - *Metal Nanoparticles
MH  - Microbial Sensitivity Tests
MH  - *Nanocomposites
MH  - Spectroscopy, Fourier Transform Infrared
MH  - *Tagetes
MH  - X-Ray Diffraction
OTO - NOTNLM
OT  - Antibacterial activity
OT  - Antioxidant activity
OT  - Au/MgO nanocomposite
OT  - Cytotoxicity
OT  - Methylene blue
OT  - Tagetes minuta
EDAT- 2021/06/05 06:00
MHDA- 2021/06/08 06:00
CRDT- 2021/06/04 05:46
PHST- 2020/12/19 00:00 [received]
PHST- 2021/04/19 00:00 [revised]
PHST- 2021/04/26 00:00 [accepted]
PHST- 2021/06/04 05:46 [entrez]
PHST- 2021/06/05 06:00 [pubmed]
PHST- 2021/06/08 06:00 [medline]
AID - S0928-4931(21)00285-X [pii]
AID - 10.1016/j.msec.2021.112146 [doi]
PST - ppublish
SO  - Mater Sci Eng C Mater Biol Appl. 2021 Jul;126:112146. doi: 
      10.1016/j.msec.2021.112146. Epub 2021 Apr 30.