PMID- 34085478 OWN - NLM STAT- MEDLINE DCOM- 20210607 LR - 20210607 IS - 0255-2930 (Print) IS - 0255-2930 (Linking) VI - 41 IP - 6 DP - 2021 Jun 12 TI - [Adjuvant treatment of penetrating moxibustion at governor vessel for persistent allergic rhinitis of deficiency-cold syndrome]. PG - 623-7 LID - 10.13703/j.0255-2930.20201229-0002 [doi] AB - OBJECTIVE: To explore the efficacy and action mechanism of penetrating moxibustion at governor vessel for persistent allergic rhinitis of deficiency-cold syndrome. METHODS: Ninety patients with persistent allergic rhinitis of deficiency-cold syndrome were randomly divided into an observation group (n = 45) and a control group (n = 45). The patients in the control group were treated with momethasone furoate nasal spray, 2 sprays per side per time, once a day. On the basis of treatment in the control group, the patients in the observation group were additionally treated with penetrating moxibustion at governor vessel, 2 h per treatment, once a week. Both groups were treated for 4 weeks. The TCM symptom score, visual analogue scale (VAS) score and rhinoconjunctivitis quality of life questionnaire (RQLQ) score were observed in the two groups before and after treatment. The serum level of immunoglobulin E (IgE) and complete blood count of eosinophil (EOS) were measured before and after treatment, and the clinical effects were compared. RESULTS: Compared before treatment, the TCM symptom scores, VAS scores, RQLQ scores, serum levels of IgE and complete blood count of EOS in the two groups were all reduced after treatment (P<0.05), and those in the observation group were lower than those in the control group (P<0.05). The total effective rate in the observation group was 95.6% (43/45), which was higher than 82.2% (37/45) in the control group (P<0.05). CONCLUSION: Based on the momethasone furoate nasal spray, the adjuvant treatment of penetrating moxibustion at governor vessel could significantly improve the clinical symptoms in patients with persistent allergic rhinitis of deficiency-cold syndrome, and its mechanism may be related to the regulation of immune disorder. FAU - Yao, Wei-Jie AU - Yao WJ AD - Department of Otolaryngology, First Affiliated Hospital of Henan University of CM, Zhengzhou 450000, China. FAU - Liu, Pu-Zhao AU - Liu PZ AD - Department of Otolaryngology, First Affiliated Hospital of Henan University of CM, Zhengzhou 450000, China. FAU - Fan, Ya-Li AU - Fan YL AD - Department of Acupuncture and Moxibustion, Third Affiliated Hospital of Henan University of CM. FAU - Zhang, Zhi-Cheng AU - Zhang ZC AD - Department of Otolaryngology, First Affiliated Hospital of Henan University of CM, Zhengzhou 450000, China. FAU - Guo, Xiang-Dong AU - Guo XD AD - Department of Otolaryngology, First Affiliated Hospital of Henan University of CM, Zhengzhou 450000, China. FAU - Gao, Xi-Yan AU - Gao XY AD - College of Acupuncture-Moxibustion and Tuina, Henan University of CM, Zhengzhou 450008. LA - chi PT - Journal Article PT - Randomized Controlled Trial PL - China TA - Zhongguo Zhen Jiu JT - Zhongguo zhen jiu = Chinese acupuncture & moxibustion JID - 8600658 SB - IM MH - Acupuncture Points MH - Humans MH - *Moxibustion MH - Quality of Life MH - *Rhinitis, Allergic/drug therapy MH - Syndrome MH - Treatment Outcome OTO - NOTNLM OT - deficiency-cold syndrome OT - penetrating moxibustion at governor vessel OT - persistent allergic rhinitis OT - randomized controlled trial (RCT) OT - stroke EDAT- 2021/06/05 06:00 MHDA- 2021/06/08 06:00 CRDT- 2021/06/04 07:32 PHST- 2021/06/04 07:32 [entrez] PHST- 2021/06/05 06:00 [pubmed] PHST- 2021/06/08 06:00 [medline] AID - 10.13703/j.0255-2930.20201229-0002 [doi] PST - ppublish SO - Zhongguo Zhen Jiu. 2021 Jun 12;41(6):623-7. doi: 10.13703/j.0255-2930.20201229-0002.