PMID- 34088626 OWN - NLM STAT- MEDLINE DCOM- 20211109 LR - 20211109 IS - 1444-2892 (Electronic) IS - 1443-9506 (Linking) VI - 30 IP - 12 DP - 2021 Dec TI - Sex-Related Differences in Outcomes for Patients With ST Elevation Myocardial Infarction (STEMI): A Tamil Nadu-STEMI Program Subgroup Analysis. PG - 1870-1875 LID - S1443-9506(21)00498-4 [pii] LID - 10.1016/j.hlc.2021.04.017 [doi] AB - BACKGROUND: ST elevation myocardial infarction (STEMI) represents a large proportion of the clinical presentation of coronary artery disease in Indian people. Owing to multiple factors contributing to the sex difference, women with STEMI are thought to have a higher risk of adverse outcomes than men. The aim of this study was to evaluate sex-related differences in the clinical characteristics and prognosis of patients with STEMI within a system of care. METHOD: This study was a subgroup analysis of the Tamil Nadu-STEMI (TN-STEMI) program, a multicentre, prospective, observational study of a quality-improvement program studying patients with STEMI at four hub-and-spoke clusters in the southern state of Tamil Nadu, India. In total, 2,420 patients were enrolled between 2012 and 2014, and the data from all four clusters, pre- and postimplementation of integrated STEMI systems, were combined for this analysis, with a 1-year follow-up. RESULTS: The mean +/- SD age of presentation of female patients (16%) was significantly later (60.1+/-10.9 years) compared with males (84%; 53.7+/-12 years). Diabetes was more prevalent in women (35.2% vs 23.8%; p<0.001), as was hypertension (35.2% vs 22.9%; p<0.001). Symptom to first medical contact in female patients was significantly delayed compared with males (193 mins vs 170 mins; p