PMID- 34090391
OWN - NLM
STAT- MEDLINE
DCOM- 20210618
LR  - 20210618
IS  - 1471-2458 (Electronic)
IS  - 1471-2458 (Linking)
VI  - 21
IP  - 1
DP  - 2021 Jun 6
TI  - Developmental trends in early childhood and their predictors from an Indian birth 
      cohort.
PG  - 1083
LID - 10.1186/s12889-021-11147-3 [doi]
LID - 1083
AB  - BACKGROUND: Early childhood developmental pattern analyses not only project 
      future cognition potential, but also identify potential risks for possible 
      intervention. The current study evaluates developmental trends in the first 3 
      years of life and their predictors in a low and middle income country setting. 
      METHODS: Trends of early childhood development at 6, 15, 24 and 36 months of age 
      and their predictors were explored in a longitudinal community-based birth cohort 
      study in an urban slum in Vellore, South India. Development was assessed using 
      the Bayley Scales of Infant and Toddler Development-III (BSID-III). RESULTS: The 
      birth cohort enrolled 251 children with 94, 91, 91 and 87% follow-up at 6, 15, 24 
      and 36 months respectively. Child development domains of cognition, language, 
      motor and social skills showed a significant decline in scores between 6 and 
      36 months of age. Higher socioeconomic position (SEP) and nurturing home 
      environment contributed to increase in cognition scores by 1.9 and 0.9 units 
      respectively. However, stunting caused a decline in cognition scores by 
      1.7 units. Higher maternal cognition, higher SEP, and caregiver responsivity 
      positively contributed to language change over time, while higher maternal 
      depression contributed negatively. An enriching home environment, growth 
      parameters and blood iron status had positive association with change in motor 
      skills. CONCLUSIONS: A triple intervention plan to enhance home environment and 
      nurturance, early childhood nutrient supplementation, and maternal education and 
      well-being might prevent child developmental decline in high risk settings.
FAU - Koshy, Beena
AU  - Koshy B
AUID- ORCID: 0000-0002-9058-1392
AD  - Developmental Paediatrics Unit, Christian Medical College, Vellore, 632004, 
      India. beenakurien@cmcvellore.ac.in.
FAU - Srinivasan, Manikandan
AU  - Srinivasan M
AD  - Wellcome research Unit, Christian Medical College, Vellore, 632004, India.
FAU - Bose, Anuradha
AU  - Bose A
AD  - Community Health, Christian Medical College, Vellore, 632004, India.
FAU - John, Sushil
AU  - John S
AD  - Low Cost Effective Care Unit, Christian Medical College, Vellore, 632004, India.
FAU - Mohan, Venkata Raghava
AU  - Mohan VR
AD  - Community Health, Christian Medical College, Vellore, 632004, India.
FAU - Roshan, Reeba
AU  - Roshan R
AD  - Developmental Paediatrics Unit, Christian Medical College, Vellore, 632004, 
      India.
FAU - Ramanujam, Karthikeyan
AU  - Ramanujam K
AD  - Wellcome research Unit, Christian Medical College, Vellore, 632004, India.
FAU - Kang, Gagandeep
AU  - Kang G
AD  - Wellcome research Unit, Christian Medical College, Vellore, 632004, India.
LA  - eng
GR  - GR-681/Bill and Melinda Gates Foundation/
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20210606
PL  - England
TA  - BMC Public Health
JT  - BMC public health
JID - 100968562
SB  - IM
MH  - *Child Development
MH  - Child, Preschool
MH  - Cognition
MH  - Cohort Studies
MH  - *Growth Disorders
MH  - Humans
MH  - India/epidemiology
MH  - Infant
PMC - PMC8180095
OTO - NOTNLM
OT  - Developmental trends
OT  - Early childhood
OT  - Home environment
OT  - Maternal factors
OT  - Socio-economic position
COIS- None
EDAT- 2021/06/07 06:00
MHDA- 2021/06/22 06:00
PMCR- 2021/06/06
CRDT- 2021/06/06 20:26
PHST- 2020/07/20 00:00 [received]
PHST- 2021/05/26 00:00 [accepted]
PHST- 2021/06/06 20:26 [entrez]
PHST- 2021/06/07 06:00 [pubmed]
PHST- 2021/06/22 06:00 [medline]
PHST- 2021/06/06 00:00 [pmc-release]
AID - 10.1186/s12889-021-11147-3 [pii]
AID - 11147 [pii]
AID - 10.1186/s12889-021-11147-3 [doi]
PST - epublish
SO  - BMC Public Health. 2021 Jun 6;21(1):1083. doi: 10.1186/s12889-021-11147-3.