PMID- 34101553 OWN - NLM STAT- MEDLINE DCOM- 20210624 LR - 20210624 IS - 2448-5667 (Electronic) IS - 0443-5117 (Linking) VI - 58 IP - 2 DP - 2020 Apr 13 TI - [Clinical characteristics of patients with acute myocardial infarction treated with thrombolysis]. PG - 100-107 LID - 10.24875/RMIMSS.M20000006 [doi] AB - BACKGROUND: In patients with ST elevation myocardial infarction (STEMI) thrombolytic therapy is the optimal reperfusion strategy when primary percutaneous intervention is not available. OBJECTIVE: To determine the clinical characteristics and hospital evolution of patients with STEMI who were treated with thrombolytic therapy in the Emergency department. METHOD: Retrospective and transversal study; we included all patients who were diagnosed with STEMI in the Emergency department of the Hospital General Regional No. 46 and received thrombolytic therapy, within a 12 month period. RESULTS: We analyzed 59 cases, with a mean age of 62.2 years old, 70% were male sex; the average age for men was 60 years (range 38-84) and for women was 71 years (range 43-87); according to the initial electrocardiogram the most common myocardial affected regions were inferior (43.8%) and extense anterior (43.8%); tenecteplase was the most used thrombolytic therapy (93%), with an average door in-needle time of 82 minutes (range 10-360 min), 52.6% met clinical criteria for reperfusion; in 49 cases a cardiac catheterism was performed in subsequent days, 49% of them was for rescue percutaneous coronary intervention; in-hospital mortality was 28%. CONCLUSIONS: Thrombolytic therapy in STEMI is effective and increases the opportunity for preserving myocardial tissue; in our institute, its mandatory that such therapy is easily available and used, taking into account the patient referral times to a hospital with catheterism laboratory. CI - Copyright: (c) 2020 Revista Medica del Instituto Mexicano del Seguro Social. FAU - Mora-Solorzano, Lizbeth AU - Mora-Solorzano L AD - Instituto Mexicano del Seguro Social, Hospital de Especialidades Centro Medico Nacional de Occidente "Lic. Ignacio Garcia Tellez", Departamento de Urgencias-Admision Medica Continua. Guadalajara, Jalisco, Mexico. FAU - Gutierrez-Diaz, Gonzalo Israel AU - Gutierrez-Diaz GI AD - Instituto Mexicano del Seguro Social, Centro Medico Nacional de Occidente, Hospital de Especialidades "Lic. Ignacio Garcia Tellez", Departamento de Cardiologia-Urgencias-Admision Medica Continua. Guadalajara, Jalisco, Mexico. FAU - Gudino-Amezcua, Diego Armando AU - Gudino-Amezcua DA AD - Instituto Mexicano del Seguro Social, Centro Medico Nacional de Occidente, Hospital de Especialidades "Lic. Ignacio Garcia Tellez", Departamento de Cardiologia-Gabinete de Cardiologia. Guadalajara, Jalisco, Mexico. FAU - Rodriguez-Gonzalez, Sergio Cristopher AU - Rodriguez-Gonzalez SC AD - Instituto Mexicano del Seguro Social, Hospital General Regional No. 46, Departamento de Urgencias Adultos. Guadalajara, Jalisco, Mexico. LA - spa PT - Journal Article TT - Caracteristicas clinicas de pacientes con infarto agudo de miocardio tratados con trombolisis. DEP - 20200413 PL - Mexico TA - Rev Med Inst Mex Seguro Soc JT - Revista medica del Instituto Mexicano del Seguro Social JID - 101243727 SB - IM MH - Adult MH - Aged MH - Aged, 80 and over MH - Female MH - Humans MH - Male MH - Middle Aged MH - *Myocardial Infarction/diagnosis/drug therapy MH - *Percutaneous Coronary Intervention MH - Retrospective Studies MH - *ST Elevation Myocardial Infarction/diagnosis/drug therapy MH - Thrombolytic Therapy MH - Treatment Outcome OTO - NOTNLM OT - Cardiac Catheterization OT - ST Elevation Myocardial Infarction OT - Thrombolytic Therapy EDAT- 2020/01/01 00:00 MHDA- 2021/06/25 06:00 CRDT- 2021/06/08 17:27 PHST- 2021/06/08 17:27 [entrez] PHST- 2020/01/01 00:00 [pubmed] PHST- 2021/06/25 06:00 [medline] AID - j58/2/100 [pii] AID - 10.24875/RMIMSS.M20000006 [doi] PST - epublish SO - Rev Med Inst Mex Seguro Soc. 2020 Apr 13;58(2):100-107. doi: 10.24875/RMIMSS.M20000006.