PMID- 34102530
OWN - NLM
STAT- MEDLINE
DCOM- 20210720
LR  - 20210720
IS  - 1873-4367 (Electronic)
IS  - 0927-7765 (Linking)
VI  - 205
DP  - 2021 Sep
TI  - Long-lasting hydrophilic surface generated on poly(dimethyl siloxane) with 
      photoreactive zwitterionic polymers.
PG  - 111900
LID - S0927-7765(21)00344-1 [pii]
LID - 10.1016/j.colsurfb.2021.111900 [doi]
AB  - Poly(dimethylsiloxane) (PDMS) is known as one of the most established polymers 
      for making elastomers. Therefore, it is commonly used for the fabrication of 
      biomedical devices. Many PDMS surface modification processes have been proposed 
      recently to increase PDMS reliability in medical fields. However, the modified 
      surface's long-term stability is still limited. Hydrophobic recovery of PDMS is 
      widely recognized as a factor that reduces the efficacy of PDMS surface 
      modification. The photoreactive zwitterionic polymer effectively suppresses the 
      hydrophobic recovery of PDMS, according to the current analysis. The 
      photoreactive zwitterionic monomer, 2-[2-(Methacryloyloxy)ethyldimethylanmmonium] 
      ethyl benzophenoxy phosphate (MBPP) was polymerized by conventional radical 
      polymerization and coated on O(2)-plasma-treated PDMS specimens. The specimens 
      were immersed in an aqueous solution of 2-methacryloyloxyethyl phosphorylcholine 
      (MPC) and exposed under ultraviolet (UV) radiation for 3 h. Instead, of 
      poly(MBPP) (PMBPP), benzophenone (BP) was also used as a conventional 
      photoinitiator. The time-dependent change in the wettability and elemental 
      composition of the specimen surface was monitored for nine weeks after 
      photo-grafting of poly[2-methacryloyloxyethyl phosphorylcholine (MPC)] (PMPC). 
      The advancing and receding contact angles (theta(A)/theta(R)) of the pristine PDMS 
      specimen were 112 degrees /71 degrees  and significantly decreased immediately after the grafting 
      of PMPC regardless of types of photoinitiator. However, the hydrophobicity of the 
      surface gradually recovered, and theta(A) was changed from 12 degrees  to 81 degrees  for nine weeks 
      of storage under air atmosphere when BP was used as a photoinitiator for graft 
      polymerization of MPC. However, surface hydrophilicity (theta(A)  congruent with 20 degrees ) of the 
      surface grafted with PMPC with PMBPP as an initiator was effectively preserved 
      for nine weeks. This surface also showed excellent lubricity and non-fouling 
      properties regardless of the storage periods. Therefore, zwitterionic 
      photoreactive polymer, PMBPP, is then used as a macrophotoinitiator for the 
      surface modification of PDMS.
CI  - Copyright (c) 2021 Elsevier B.V. All rights reserved.
FAU - Nakano, Hiroki
AU  - Nakano H
AD  - Graduate School of Science and Engineering, Kansai University, 3-3-35 Yamate-cho, 
      Suita-shi, Osaka, 564-8680, Japan.
FAU - Kakinoki, Sachiro
AU  - Kakinoki S
AD  - Faculty of Chemistry, Materials and Bioengineering, Kansai University, 3-3-35 
      Yamate-cho, Suita-shi, Osaka, 564-8680, Japan; Organization for Research and 
      Development of Innovative Science and Technology, Kansai University, 3-3-35 
      Yamate-cho, Suita-shi, Osaka, 564-8680, Japan.
FAU - Iwasaki, Yasuhiko
AU  - Iwasaki Y
AD  - Faculty of Chemistry, Materials and Bioengineering, Kansai University, 3-3-35 
      Yamate-cho, Suita-shi, Osaka, 564-8680, Japan; Organization for Research and 
      Development of Innovative Science and Technology, Kansai University, 3-3-35 
      Yamate-cho, Suita-shi, Osaka, 564-8680, Japan. Electronic address: 
      yasu.bmt@kansai-u.ac.jp.
LA  - eng
PT  - Journal Article
DEP - 20210602
PL  - Netherlands
TA  - Colloids Surf B Biointerfaces
JT  - Colloids and surfaces. B, Biointerfaces
JID - 9315133
RN  - 0 (Methacrylates)
RN  - 0 (Polymers)
RN  - 0 (Siloxanes)
RN  - 107-73-3 (Phosphorylcholine)
SB  - IM
MH  - Hydrophobic and Hydrophilic Interactions
MH  - Methacrylates
MH  - Phosphorylcholine
MH  - *Polymers
MH  - Reproducibility of Results
MH  - *Siloxanes
MH  - Surface Properties
OTO - NOTNLM
OT  - Biofouling
OT  - Hydrophobic recovery
OT  - Lubricity
OT  - PDMS
OT  - Surface modification
OT  - Zwitterionic polymer
EDAT- 2021/06/09 06:00
MHDA- 2021/07/21 06:00
CRDT- 2021/06/08 20:51
PHST- 2021/05/14 00:00 [received]
PHST- 2021/05/27 00:00 [revised]
PHST- 2021/05/29 00:00 [accepted]
PHST- 2021/06/09 06:00 [pubmed]
PHST- 2021/07/21 06:00 [medline]
PHST- 2021/06/08 20:51 [entrez]
AID - S0927-7765(21)00344-1 [pii]
AID - 10.1016/j.colsurfb.2021.111900 [doi]
PST - ppublish
SO  - Colloids Surf B Biointerfaces. 2021 Sep;205:111900. doi: 
      10.1016/j.colsurfb.2021.111900. Epub 2021 Jun 2.