PMID- 34104996
OWN - NLM
STAT- MEDLINE
DCOM- 20211223
LR  - 20211223
IS  - 1436-5073 (Electronic)
IS  - 0026-3672 (Linking)
VI  - 188
IP  - 7
DP  - 2021 Jun 9
TI  - Tannic acid-directed synthesis of magnetic and boronic acid-functionalized 
      metal-organic frameworks for selective extraction and quantification of 
      catecholamines in human urine.
PG  - 225
LID - 10.1007/s00604-021-04852-8 [doi]
AB  - A novel magnetic borate-functionalized metal-organic framework nanocomposite was 
      designed and fabricated for selective enrichment of catecholamines from human 
      urine. Firstly, the polytannic acid (PTA) layer with natural low-cost and 
      ecofriendly polyphenol tannic acid as the organic ligand and Fe(3+) as the 
      cross-linker was coated onto the surface of Fe(3)O(4). Then, the 
      borate-functionalized metal-organic framework (MIL-100(Fe)-B) with 
      5-boronobenzene-1,3-dicarboxylic acid as a ligand fragment was modified onto the 
      PTA-coated Fe(3)O(4) through a metal-ligand-fragment coassembly strategy. The 
      obtained smart porous adsorbent Fe(3)O(4)@PTA@MIL-100(Fe)-B was confirmed by 
      means of several characterization methods and then applied as an effective 
      magnetic solid phase extraction (MSPE) sorbent for specific extraction of trace 
      catecholamines in human urine. The Plackett-Burman design was used for screening 
      the variables significantly affecting the extraction efficiency. Then, the 
      significant factors were further investigated by the Box-Behnken design to 
      determine the optimal extraction conditions. Under the optimal conditions, a 
      method for selective MSPE combined with high-performance liquid chromatography 
      with a fluorescence detector for the quantitation of catecholamines in human 
      urine was developed and validated. With the proposed method, the linearity range 
      was from 0.500 to 500 ng mL(-1) for norepinephrine and epinephrine and from 1.00 
      to 500 ng mL(-1) for dopamine. The detection limits were 0.050, 0.11, and 
      0.20 ng mL(-1) for norepinephrine, epinephrine, and dopamine, respectively. The 
      recoveries from spiking experiments varied from 91.5 to 108% with relative 
      standard deviations (RSDs) of 0.80-4.8%. The established method is rapid, 
      sensitive, accurate, inexpensive, and ecofriendly and was successfully applied to 
      the determination of the target catecholamines in human urine samples.
FAU - Xing, Yanyan
AU  - Xing Y
AD  - School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, Liaoning 
      Province, People's Republic of China.
FAU - Li, Jianshu
AU  - Li J
AD  - School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, 
      Shenyang, Liaoning Province, 110016, People's Republic of China.
FAU - Chen, Meiling
AU  - Chen M
AD  - School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, Liaoning 
      Province, People's Republic of China.
FAU - Wang, Xiangting
AU  - Wang X
AD  - School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, Liaoning 
      Province, People's Republic of China.
FAU - Hou, Xiaohong
AU  - Hou X
AD  - School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, 
      Shenyang, Liaoning Province, 110016, People's Republic of China. 
      syphu_houxiaohong@163.com.
LA  - eng
PT  - Journal Article
DEP - 20210609
PL  - Austria
TA  - Mikrochim Acta
JT  - Mikrochimica acta
JID - 7808782
RN  - 0 (Boronic Acids)
RN  - 0 (Catecholamines)
RN  - 0 (Metal-Organic Frameworks)
RN  - 0 (Tannins)
SB  - IM
MH  - Boronic Acids/*metabolism
MH  - Catecholamines/*urine
MH  - Humans
MH  - Magnetic Phenomena
MH  - Metal-Organic Frameworks/*metabolism
MH  - Tannins/*metabolism
OTO - NOTNLM
OT  - Catecholamines in human urine
OT  - Magnetic borate-functionalized metal-organic framework
OT  - Selective extraction and separation
OT  - Tannic acid
EDAT- 2021/06/10 06:00
MHDA- 2021/12/24 06:00
CRDT- 2021/06/09 06:55
PHST- 2021/02/14 00:00 [received]
PHST- 2021/05/11 00:00 [accepted]
PHST- 2021/06/09 06:55 [entrez]
PHST- 2021/06/10 06:00 [pubmed]
PHST- 2021/12/24 06:00 [medline]
AID - 10.1007/s00604-021-04852-8 [pii]
AID - 10.1007/s00604-021-04852-8 [doi]
PST - epublish
SO  - Mikrochim Acta. 2021 Jun 9;188(7):225. doi: 10.1007/s00604-021-04852-8.