PMID- 34105856
OWN - NLM
STAT- MEDLINE
DCOM- 20210817
LR  - 20210817
IS  - 1742-1241 (Electronic)
IS  - 1368-5031 (Linking)
VI  - 75
IP  - 9
DP  - 2021 Sep
TI  - Clinical outcomes of Covid-19 in patients with rheumatic diseases and the effects 
      of the pandemic on rheumatology outpatient care: A single-centre experience from 
      Turkey.
PG  - e14442
LID - 10.1111/ijcp.14442 [doi]
AB  - OBJECTIVE: The aim of the study was to detect the frequency and course of 
      coronavirus disease 2019 (Covid-19) infection among our rheumatology outpatients 
      and to investigate how patient follow-up differed during Covid-19 pandemic in a 
      tertiary University Hospital in the capital of Turkey. PATIENTS AND METHOD: 
      Patients with inflammatory rheumatic diseases (IRDs) registered in our 
      rheumatology clinic were assessed during their routine outpatient follow-up 
      control or contacted via phone between July and December 2020. Patients' 
      demographics, diagnosis, medication, comorbidities, frequency of going outside 
      during the pandemic, work status, whether patients could attend their routine 
      follow-up, treatment changes, access to drugs during the pandemic, and the 
      incidence of Covid-19 infection were collected. RESULTS: A total of 320 patients 
      with IRD were analysed; 114 (35.6%) patients were treated with conventional 
      synthetic disease-modifying antirheumatic drugs (csDMARDs) 
      (methotrexate/leflunomide/sulfasalazine), 93 (29.1%) patients with biologic 
      DMARDs (bDMARDs), 113 (35.3%) patients with glucocorticoids, and 103 (32.2%) 
      patients with hydroxychloroquine (HCQ). A total of 15.9% of patients on HCQ 
      experienced problems in medication supply. Only 87 (27.2%) patients presented for 
      their routine follow-up appointment, and 38 (11.9%) of the patients changed their 
      treatment without professional health advice. While 53 (57%) patients on 
      biological agents continued their treatment, 31 patients (33.3%) interrupted the 
      treatment with doctor's recommendation and 9 patients (9.6%) on their initiative, 
      and 23 of these 31 patients had to restart treatment because of disease 
      activation. The nasopharyngeal swab collected from 30 patients with a suspected 
      Covid-19 contact but without any symptoms was negative. In total, there were 33 
      patients diagnosed with Covid-19; none of whom had severe respiratory 
      complications or death. CONCLUSIONS: Many patients with rheumatic diseases are 
      left without disease monitoring during the pandemic. There was no increased risk 
      of severe Covid-19 infection among patients with IRD.
CI  - (c) 2021 John Wiley & Sons Ltd.
FAU - Batibay, Sevilay
AU  - Batibay S
AUID- ORCID: 0000-0002-6286-3632
AD  - Division of Rheumatology, Department of Physical and Rehabilitation Medicine, 
      Faculty of Medicine, Gazi University, Ankara, Turkey.
FAU - Kocak Ulucakoy, Rezan
AU  - Kocak Ulucakoy R
AUID- ORCID: 0000-0001-6206-4841
AD  - Division of Rheumatology, Department of Physical and Rehabilitation Medicine, 
      Faculty of Medicine, Gazi University, Ankara, Turkey.
FAU - Ozdemir, Baki
AU  - Ozdemir B
AUID- ORCID: 0000-0001-9026-7750
AD  - Division of Rheumatology, Department of Physical and Rehabilitation Medicine, 
      Faculty of Medicine, Gazi University, Ankara, Turkey.
FAU - Gunendi, Zafer
AU  - Gunendi Z
AUID- ORCID: 0000-0003-0696-5834
AD  - Division of Rheumatology, Department of Physical and Rehabilitation Medicine, 
      Faculty of Medicine, Gazi University, Ankara, Turkey.
FAU - Gogus, Feride Nur
AU  - Gogus FN
AUID- ORCID: 0000-0003-0921-5991
AD  - Division of Rheumatology, Department of Physical and Rehabilitation Medicine, 
      Faculty of Medicine, Gazi University, Ankara, Turkey.
LA  - eng
PT  - Journal Article
DEP - 20210627
PL  - India
TA  - Int J Clin Pract
JT  - International journal of clinical practice
JID - 9712381
RN  - 0 (Antirheumatic Agents)
SB  - IM
MH  - Ambulatory Care
MH  - *Antirheumatic Agents/therapeutic use
MH  - *COVID-19
MH  - Humans
MH  - Pandemics
MH  - *Rheumatic Diseases/drug therapy/epidemiology
MH  - *Rheumatology
MH  - SARS-CoV-2
MH  - Turkey/epidemiology
EDAT- 2021/06/10 06:00
MHDA- 2021/08/18 06:00
CRDT- 2021/06/09 08:56
PHST- 2021/04/21 00:00 [revised]
PHST- 2021/01/18 00:00 [received]
PHST- 2021/05/14 00:00 [accepted]
PHST- 2021/06/10 06:00 [pubmed]
PHST- 2021/08/18 06:00 [medline]
PHST- 2021/06/09 08:56 [entrez]
AID - 10.1111/ijcp.14442 [doi]
PST - ppublish
SO  - Int J Clin Pract. 2021 Sep;75(9):e14442. doi: 10.1111/ijcp.14442. Epub 2021 Jun 
      27.