PMID- 34106663
OWN - NLM
STAT- MEDLINE
DCOM- 20210622
LR  - 20210622
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Print)
IS  - 0025-7974 (Linking)
VI  - 100
IP  - 19
DP  - 2021 May 14
TI  - Type 2 diabetes and the risk of colorectal polyps: A retrospective nationwide 
      population-based study.
PG  - e25933
LID - 10.1097/MD.0000000000025933 [doi]
LID - e25933
AB  - The incidence rates of type 2 diabetes mellitus (T2DM) and colorectal polyps have 
      been increasing over the last decades. However, direct associations between T2DM 
      and colorectal polyps have not been extensively reported. We will explore the 
      relationship between T2DM and colorectal polyps.In the retrospective study, we 
      classified DM and NonDM groups (control) from 993,516 people in Taiwan nationwide 
      population insurance database from the period of 2000 to 2013. We collected data 
      on income and comorbidities through the international classification of diseases, 
      ninth revision-clinical modification (ICD-9-CM) codes.The T2DM group had a higher 
      incidence rate of colorectal polyps (31.97%, 95% confidence interval [CI] = 
      30.97-33.28) than the control group (25.9%, 95% CI = 25.1-26.72), and the crude 
      incidence ratio was 1.235 (95% CI = 1.174-1.300). In 13 years of follow-up 
      (2000-2013), T2DM was linked to a significantly higher cumulative probability of 
      colorectal polyps (log-rank test: P = .0001).Patients with T2DM had a 1.23-fold 
      higher risk of new colorectal polyps than control patients in 13 years of 
      follow-up. We explain the T2DM increases incidence for colorectal polyps in long 
      term follow-up.
CI  - Copyright (c) 2021 the Author(s). Published by Wolters Kluwer Health, Inc.
FAU - Hsu, Po-Ke
AU  - Hsu PK
AD  - Department of Gastroenterology, Changhua Christian Hospital, Changhua.
AD  - Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan.
FAU - Huang, Jing-Yang
AU  - Huang JY
AD  - Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan.
FAU - Su, Wei-Wen
AU  - Su WW
AD  - Department of Gastroenterology, Changhua Christian Hospital, Changhua.
FAU - Wei, James Cheng-Chung
AU  - Wei JC
AD  - Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan.
LA  - eng
PT  - Journal Article
PT  - Observational Study
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
SB  - IM
MH  - Adult
MH  - Aged
MH  - Colonic Polyps/*epidemiology
MH  - Comorbidity
MH  - Diabetes Mellitus, Type 2/*epidemiology
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Retrospective Studies
MH  - Socioeconomic Factors
MH  - Taiwan/epidemiology
PMC - PMC8133214
COIS- The authors have no conflict of interest.
EDAT- 2021/06/10 06:00
MHDA- 2021/06/23 06:00
PMCR- 2021/05/14
CRDT- 2021/06/09 16:59
PHST- 2020/05/16 00:00 [received]
PHST- 2021/04/17 00:00 [accepted]
PHST- 2021/06/09 16:59 [entrez]
PHST- 2021/06/10 06:00 [pubmed]
PHST- 2021/06/23 06:00 [medline]
PHST- 2021/05/14 00:00 [pmc-release]
AID - 00005792-202105140-00083 [pii]
AID - MD-D-20-04111 [pii]
AID - 10.1097/MD.0000000000025933 [doi]
PST - ppublish
SO  - Medicine (Baltimore). 2021 May 14;100(19):e25933. doi: 
      10.1097/MD.0000000000025933.