PMID- 34109285 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20240320 IS - 2514-2119 (Electronic) IS - 2514-2119 (Linking) VI - 3 IP - 4 DP - 2019 Dec TI - A case report of eosinophilic granulomatosis and polyangiitis myocarditis presenting as ST elevation myocardial infarction and showing positive response to immunotherapy. PG - 1-6 LID - 10.1093/ehjcr/ytz161 [doi] AB - BACKGROUND: Acute ST elevation myocardial infarction (STEMI) is a medical emergency and is most commonly due to atherosclerotic plaque rupture and occlusion of coronary vessels. This case demonstrates that eosinophilic granulomatosis with polyangiitis (EGPA) myocarditis can mimic acute STEMI. CASE SUMMARY: A 44-year-old woman presented with acute chest pain, shortness of breath, and collapse with ST elevation on electrocardiography. Coronary angiogram showed unobstructed coronaries and chest film revealed left-sided consolidation. Together with a thorough history, serum eosinophilia, cardiac magnetic resonance (CMR), and computated tomography imaging, the patient was diagnosed with acute EGPA myocarditis. She responded tremendously to steroid and cyclophosphamide immunosuppression and subsequent CMR imaging demonstrated complete resolution of myocarditis. DISCUSSION: CMR played a crucial role in the diagnosis and follow-up of this rare presentation. In patients who present as a STEMI but show unobstructed coronary vessels, EGPA may be a possible diagnosis. CI - (c) The Author(s) 2019. Published by Oxford University Press on behalf of the European Society of Cardiology. FAU - Gill, Jaspal Singh AU - Gill JS AUID- ORCID: 0000-0001-9246-5371 AD - Cardiology Department, Royal Free Hospital, Pond Street, London NW3 2QG, UK. FAU - Fontana, Marianna AU - Fontana M AUID- ORCID: 0000-0002-9233-9831 AD - Cardiology Department, Royal Free Hospital, Pond Street, London NW3 2QG, UK. FAU - Knight, Daniel AU - Knight D AD - Cardiology Department, Royal Free Hospital, Pond Street, London NW3 2QG, UK. FAU - Kalra, Sundeep Singh AU - Kalra SS AUID- ORCID: 0000-0002-1292-6973 AD - Cardiology Department, Royal Free Hospital, Pond Street, London NW3 2QG, UK. LA - eng GR - FS/18/21/33447/BHF_/British Heart Foundation/United Kingdom PT - Case Reports DEP - 20191026 PL - England TA - Eur Heart J Case Rep JT - European heart journal. Case reports JID - 101730741 PMC - PMC8183649 OTO - NOTNLM OT - Cardiac magnetic resonance imaging OT - Case report OT - Eosinophilic granulomatosis with polyangiitis (Churg-Strauss) OT - Myocarditis OT - ST elevation myocardial infarction EDAT- 2019/10/26 00:00 MHDA- 2019/10/26 00:01 PMCR- 2019/10/26 CRDT- 2021/06/10 06:48 PHST- 2019/01/06 00:00 [received] PHST- 2019/03/08 00:00 [revised] PHST- 2019/10/22 00:00 [accepted] PHST- 2021/06/10 06:48 [entrez] PHST- 2019/10/26 00:00 [pubmed] PHST- 2019/10/26 00:01 [medline] PHST- 2019/10/26 00:00 [pmc-release] AID - ytz161 [pii] AID - 10.1093/ehjcr/ytz161 [doi] PST - epublish SO - Eur Heart J Case Rep. 2019 Oct 26;3(4):1-6. doi: 10.1093/ehjcr/ytz161. eCollection 2019 Dec.