PMID- 34111767 OWN - NLM STAT- MEDLINE DCOM- 20210630 LR - 20210630 IS - 1525-5069 (Electronic) IS - 1525-5050 (Linking) VI - 121 IP - Pt A DP - 2021 Aug TI - Individual prediction of motor vehicle accidents for patients with epilepsy. PG - 108046 LID - S1525-5050(21)00280-8 [pii] LID - 10.1016/j.yebeh.2021.108046 [doi] AB - The objective of the study was to design a clinically useful tool to predict the risk of seizure-related motor vehicle accidents (MVAs) for people with epilepsy (PWE). Participants were patients who visited our epilepsy center in West China Hospital from October 2012 to October 2019 and were divided into a primary cohort and a validation cohort. Ultimately, we included 525 patients in the primary cohort and 86 patients in the validation cohort. Proportional hazard regression was performed to measure the prognostic factors of car accidents. The outcome was used to create a nomogram model. The final model had 7 factors, with a C-index of 0.85 (95% CI, 0.80-0.91), to predict the possibility of non-MVA for PWE. For the validation cohort, the C-index was 0.83 (95% CI, 0.72-0.95). This nomogram model can offer more individualized advice to PWE who are still driving by estimating the risk of car accidents. CI - Copyright (c) 2021 The Authors. Published by Elsevier Inc. All rights reserved. FAU - Lin, Mintao AU - Lin M AD - Department of Neurology, West China Hospital, Sichuan University, No. 37 Guoxue Road, Chengdu, Sichuan 610041, People's Republic of China. FAU - Chen, Jiani AU - Chen J AD - Department of Neurology, West China Hospital, Sichuan University, No. 37 Guoxue Road, Chengdu, Sichuan 610041, People's Republic of China. FAU - Li, Sisi AU - Li S AD - Department of Neurology, West China Hospital, Sichuan University, No. 37 Guoxue Road, Chengdu, Sichuan 610041, People's Republic of China. FAU - Qin, Yingjie AU - Qin Y AD - Department of Neurology, West China Hospital, Sichuan University, No. 37 Guoxue Road, Chengdu, Sichuan 610041, People's Republic of China. FAU - Wang, Xuruan AU - Wang X AD - West China Medical School, Sichuan University, No. 37 Guoxue Road, Chengdu, Sichuan 610041, People's Republic of China. FAU - Liu, Yadong AU - Liu Y AD - West China Medical School, Sichuan University, No. 37 Guoxue Road, Chengdu, Sichuan 610041, People's Republic of China. FAU - Zhang, Qi AU - Zhang Q AD - Department of Neurology, West China Hospital, Sichuan University, No. 37 Guoxue Road, Chengdu, Sichuan 610041, People's Republic of China. FAU - Taha Abdullah Abdulaziz, Ammar AU - Taha Abdullah Abdulaziz A AD - Department of Neurology, West China Hospital, Sichuan University, No. 37 Guoxue Road, Chengdu, Sichuan 610041, People's Republic of China. FAU - Zhou, Dong AU - Zhou D AD - Department of Neurology, West China Hospital, Sichuan University, No. 37 Guoxue Road, Chengdu, Sichuan 610041, People's Republic of China. Electronic address: zhoudong66@yahoo.de. FAU - Li, Jinmei AU - Li J AD - Department of Neurology, West China Hospital, Sichuan University, No. 37 Guoxue Road, Chengdu, Sichuan 610041, People's Republic of China. Electronic address: lijinmei@wchscu.cn. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20210607 PL - United States TA - Epilepsy Behav JT - Epilepsy & behavior : E&B JID - 100892858 SB - IM MH - Accidents, Traffic MH - *Automobile Driving MH - China/epidemiology MH - *Epilepsy/epidemiology MH - Humans MH - Motor Vehicles OTO - NOTNLM OT - Epilepsy OT - Motor vehicle accidents OT - Nomogram OT - Prediction EDAT- 2021/06/11 06:00 MHDA- 2021/07/01 06:00 CRDT- 2021/06/10 20:23 PHST- 2021/01/13 00:00 [received] PHST- 2021/04/29 00:00 [revised] PHST- 2021/04/30 00:00 [accepted] PHST- 2021/06/11 06:00 [pubmed] PHST- 2021/07/01 06:00 [medline] PHST- 2021/06/10 20:23 [entrez] AID - S1525-5050(21)00280-8 [pii] AID - 10.1016/j.yebeh.2021.108046 [doi] PST - ppublish SO - Epilepsy Behav. 2021 Aug;121(Pt A):108046. doi: 10.1016/j.yebeh.2021.108046. Epub 2021 Jun 7.